Zobrazeno 1 - 10
of 1 095
pro vyhledávání: '"Non-alcoholic steatohepatitis (NASH)"'
Autor:
Huan Zhang, Yongqiang He, Yuqing Zhao, Malina Axinbai, Yuwei Hu, Shilei Liu, Jingmin Kong, Jinhui Sun, Liping Zhang
Publikováno v:
Hereditas, Vol 161, Iss 1, Pp 1-14 (2024)
Abstract Background The most common progressive form of non-alcoholic fatty liver disease (NAFLD) is non-alcoholic steatohepatitis (NASH), which is characterized by the development of cirrhosis, and requires liver transplantation. We screened for the
Externí odkaz:
https://doaj.org/article/8effe56cc7ed4c52ba08d6782c5a87e5
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The farnesoid X receptor (FXR) is a crucial therapeutic target for treating non-alcoholic steatohepatitis (NASH). Although obeticholic acid (OCA) as a FXR agonist presents good efficacy, the safety data such as severe pruritus should be care
Externí odkaz:
https://doaj.org/article/454a6311bf3c4c40a22be314906d42dd
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/ba7cfb30dfe8400ba334d62d62dc899a
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/f76e337666a741bfabf60f24f3fb5aaf
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract The co-existence of inflammatory bowel disease (IBD) and non-alcoholic steatohepatitis (NASH) has raised interest in identifying shared molecular mechanisms and potential therapeutic targets. However, the relationship between these two disea
Externí odkaz:
https://doaj.org/article/730aa458bc7b43d8ad0470ab4002c541
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide, and its prevalence is rapidly increasing. Antioxidants, lipid-lowering medications, and lifestyle interventions are the most commonly used treatment options
Externí odkaz:
https://doaj.org/article/934dd7ffbb314799b288ace4010d9496
Autor:
Reddemma Sandireddy, Suganya Sakthivel, Priyanka Gupta, Jatin Behari, Madhulika Tripathi, Brijesh Kumar Singh
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Metabolic dysfunction-associated steatotic liver disease (MASLD), previously known as non-alcoholic fatty liver disease (NAFLD), is the most common liver disorder worldwide, with an estimated global prevalence of more than 31%. Metabolic dysfunction-
Externí odkaz:
https://doaj.org/article/2743a4cc294e4557961a319afae5bacc
Autor:
Nafiseh Sadeghi, Saleh Rahmati
Publikováno v:
Journal of Mazandaran University of Medical Sciences, Vol 34, Iss 231, Pp 54-61 (2024)
Background and purpose: High-intensity interval training (HIIT) affects the expression of genes altered by obesity and non-alcoholic fatty liver disease. Perilipins (PLINs) are a family of five proteins that are expressed on the surface of fat drople
Externí odkaz:
https://doaj.org/article/13381a31b91049fb93547f6364e0b5da
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Aim To understand how liver sinusoidal endothelial cells (LSECs) respond to nonalcoholic steatohepatitis (NASH). Methods We profiled single-LSEC from livers of control and MCD-fed mice. The functions of C-Kit +-LSECs were determined using co
Externí odkaz:
https://doaj.org/article/6b318f011ecf4104bf823099b5ed0b20
Autor:
Mireille Khoury, Qianqian Guo, Kunimaro Furuta, Cristina Correia, Chady Meroueh, Hyun Se Kim Lee, Khaled Warasnhe, Lucía Valenzuela-Pérez, Andrew P. Mazar, Iljung Kim, Yung-Kyun Noh, Heather Holmes, Michael F. Romero, Caroline R. Sussman, Kevin D. Pavelko, Shahidul Islam, Adebowale O. Bamidele, Petra Hirsova, Hu Li, Samar H. Ibrahim
Publikováno v:
JHEP Reports, Vol 6, Iss 6, Pp 101073- (2024)
Background & Aims: Metabolic dysfunction-associated steatohepatitis (MASH) is characterized by excessive circulating toxic lipids, hepatic steatosis, and liver inflammation. Monocyte adhesion to liver sinusoidal endothelial cells (LSECs) and transend
Externí odkaz:
https://doaj.org/article/140f68733e754e61917380b70dbef94e