Výsledky vyhledávání - "Non-Histone/metabolism"

Dangerous liaisons: interplay between SWI/SNF, NuRD, and Polycomb in chromatin regulation and cancer

Autor: C. Peter Verrijzer, Adrian P. Bracken, Gerard L. Brien

Publikováno v: Genes & Development, 33(15-16), 936-959. Cold Spring Harbor Laboratory Press
Bracken, A P, Brien, G L & Verrijzer, C P 2019, ' Dangerous liaisons : interplay between SWI/SNF, NuRD, and Polycomb in chromatin regulation and cancer ', Genes & Development, vol. 33, no. 15-16, pp. 936-959 . https://doi.org/10.1101/gad.326066.119

Changes in chromatin structure mediated by ATP-dependent nucleosome remodelers and histone modifying enzymes are integral to the process of gene regulation. Here, we review the roles of the SWI/SNF (switch/sucrose nonfermenting) and NuRD (nucleosome

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06eafcc02254f591bbb2ec0f8800ba10
https://doi.org/10.1101/gad.326066.119

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UVR8-mediated inhibition of shade avoidance involves HFR1 stabilization in Arabidopsis

Autor: Tavridou, Eleni, Schmid-Siegert, Emanuel, Fankhauser, Christian, Ulm, Roman

Publikováno v: PLoS Genetics, Vol 16, Iss 5, p e1008797 (2020)
PLoS genetics, vol. 16, no. 5, pp. e1008797
PLoS Genetics
PLOS Genetics, Vol. 16, No 5 (2020) P. e1008797

Sun-loving plants perceive the proximity of potential light-competing neighboring plants as a reduction in the red:far-red ratio (R:FR), which elicits a suite of responses called the “shade avoidance syndrome” (SAS). Changes in R:FR are primarily

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0545b92567db39a9ed60551075590f7f
https://doaj.org/article/0e9d7e2ea96b4a92a1377c80f65a3f8f

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Nse5/6 inhibits the Smc5/6 ATPase and modulates DNA substrate binding

Autor: Taschner, Michael, Basquin, Jérôme, Steigenberger, Barbara, Schäfer, Ingmar B, Soh, Young-Min, Basquin, Claire, Lorentzen, Esben, Räschle, Markus, Scheltema, Richard A, Gruber, Stephan, Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics

Publikováno v: The EMBO Journal
Taschner, M, Basquin, J, Steigenberger, B, Schäfer, I B, Soh, Y M, Basquin, C, Lorentzen, E, Räschle, M, Scheltema, R A & Gruber, S 2021, ' Nse5/6 inhibits the Smc5/6 ATPase and modulates DNA substrate binding ', EMBO Journal, vol. 40, no. 15, e107807 . https://doi.org/10.15252/embj.2021107807
EMBO Journal, 40(15), 1. Nature Publishing Group
The EMBO journal, vol. 40, no. 15, pp. e107807

Eukaryotic cells employ three SMC (structural maintenance of chromosomes) complexes to control DNA folding and topology. The Smc5/6 complex plays roles in DNA repair and in preventing the accumulation of deleterious DNA junctions. To elucidate how sp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c17986ccfdfc0da9d0095f7c5afdede
https://doi.org/10.15252/embj.2021107807

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Kinase inhibition profiles as a tool to identify kinases for specific phosphorylation sites

Autor: Watson, N. A., Cartwright, T. N., Lawless, C., Cﾃ｡mara-Donoso, M., Sen, O., Sako, K., Hirota, T., Kimura, Hiroshi, Higgins, J. M. G.

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications

There are thousands of known cellular phosphorylation sites, but the paucity of ways to identify kinases for particular phosphorylation events remains a major roadblock for understanding kinase signaling. To address this, we here develop a generally

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fcd03979c666a3b5a7e7d4a8eecb99a
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100852403

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Arabidopsis RUP2 represses UVR8-mediated flowering in noninductive photoperiods

Autor: Song Chen, Vinicius Costa Galvão, Marie Pireyre, Roman Ulm, J. Barbro Winkler, Adriana Beatriz Arongaus, Nina Glöckner, Christian Fankhauser, Klaus Harter, Andreas Albert

Publikováno v: Genes & development, vol. 32, no. 19-20, pp. 1332-1343
Genes and Development, Vol. 32, No 19-20 (2018) pp. 1332-1343
Genes Dev. 32, 1332-1343 (2018)

Plants have evolved complex photoreceptor-controlled mechanisms to sense and respond to seasonal changes in day length. This ability allows plants to optimally time the transition from vegetative growth to flowering. UV-B is an important part intrins

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63eb6c5cd9f6e6da196c791550e705a5
https://serval.unil.ch/resource/serval:BIB_00F3008B007B.P001/REF.pdf

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Transcription-induced supercoiling as the driving force of chromatin loop extrusion during formation of TADs in interphase chromosomes

Autor: Andrzej Stasiak, Fabrizio Benedetti, Dušan Račko, Julien Dorier

Publikováno v: Nucleic acids research, vol. 46, no. 4, pp. 1648-1660
Nucleic Acids Research

Using molecular dynamics simulations, we show here that growing plectonemes resulting from transcription-induced supercoiling have the ability to actively push cohesin rings along chromatin fibres. The pushing direction is such that within each topol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6cdc946894ba1b988866afdbf5abced
https://serval.unil.ch/notice/serval:BIB_DFCB79821A40

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Microtubule detyrosination guides chromosomes during mitosis

Autor: Carsten Janke, Ana L. Pereira, Suvranta K. Tripathy, Anatoly V. Zaytsev, Maria M. Magiera, Helder Maiato, Ekaterina L. Grishchuk, Marin Barisic, Ricardo Silva e Sousa

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Before chromosomes segregate into daughter cells, they align at the mitotic spindle equator, a process known as chromosome congression. Centromere-associated protein E (CENP-E)/Kinesin-7 is a microtubule plus-end-directed kinetochore motor required f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae16d669e28eecb53df4c0b4cb413103
https://doi.org/10.1126/science.aaa5175

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Molecular mechanism of dynein recruitment to kinetochores by the Rod-Zw10-Zwilch complex and Spindly

Autor: Patrícia A. Simões, Reto Gassmann, Cátia de Carvalho, Rita M. Reis, Daniel José Barbosa, Ricardo Celestino, Dhanya K. Cheerambathur, Helena R. Pires, Cláudia Pereira, José B. Gama, Ana Carvalho, João Amorim

Publikováno v: Gama, J B, Pereira, C, Simões, P A, Celestino, R, Reis, R M, Barbosa, D J, Pires, H R, Carvalho, C, Amorim, J, Carvalho, A X, Cheerambathur, D K & Gassmann, R 2017, ' Molecular mechanism of dynein recruitment to kinetochores by the Rod-Zw10-Zwilch complex and Spindly ', Journal of Cell Biology, vol. 216, no. 4, pp. 943-960 . https://doi.org/10.1083/jcb.201610108
The Journal of Cell Biology
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

The dynein motor is recruited to the kinetochore to capture spindle microtubules and control the spindle assembly checkpoint. Gama et al. reveal the molecular mechanism of how the Rod–Zw10–Zwilch complex and Spindly mediate dynein recruitment in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e4dd69b6f9537932d3a7a0ac63af051
https://hdl.handle.net/20.500.11820/cfdc5439-c4c9-435e-8386-09e192882255

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