Zobrazeno 1 - 10
of 2 661
pro vyhledávání: '"Non cancer"'
Publikováno v:
Scandinavian Journal of Primary Health Care, Pp 1-4 (2024)
Objective Is the involvement of the regular general practitioner (GP) in the decision to initiate opioid treatment for chronic non-cancer pain (CNCP) associated with two main risk factors for serious adverse events: increased opioid dose and the conc
Externí odkaz:
https://doaj.org/article/28f90dc5ef3e487b8343acf23180a705
Autor:
Nils Frederik Schrader, Anja Niemann, Milena Weitzel, Christian Speckemeier, Carina Abels, Nikola Blase, Godwin Denk Giebel, Cordula Riederer, Joachim Nadstawek, Wolfgang Straßmeir, Jürgen Wasem, Silke Neusser
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background High-dose long-term opioid therapy (LTOT) has been associated with increased mortality and hospitalizations. Therefore, the evidence-based German guideline on LTOT for chronic non-cancer pain (CNCP) recommends to only exceed the m
Externí odkaz:
https://doaj.org/article/644d4b6ed32d47969ab65d8a13715239
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-9 (2024)
Abstract Background The Correa’s cascade, encompassing chronic non-atrophic gastritis, atrophic gastritis, intestinal metaplasia, and dysplasia, represents the well-recognized pathway for the development of non-cardia gastric cancer. Population-bas
Externí odkaz:
https://doaj.org/article/03bb171b1a19426b8132033d450b45af
Determination of heavy metals and health risk assessment in drinking water in Jigjiga City, Ethiopia
Publikováno v:
Discover Environment, Vol 2, Iss 1, Pp 1-21 (2024)
Abstract Water is essential to life on Earth, yet heavy metal concentrations in it can have negative consequences on people's health. This study was designed to measure the levels of seven heavy metals (Fe, Zn, Cu, Pb, Cr, Cd, and Ni) in the drinking
Externí odkaz:
https://doaj.org/article/0b3907c42b344fb3b536b1f96c060bb1
Autor:
Shamaila Yousaf, Komal Shahzadi
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
The exploration of non-cancer medications with potential anti-cancer activity offers a promising avenue for drug repurposing, accelerating the development of new oncological therapies. This study employs Quantitative Structure-Property Relationship (
Externí odkaz:
https://doaj.org/article/263cee836cca44d587f6b31db1f4c2f5
Autor:
Yuki Ushimaru, Shinnosuke Nagano, Kazuhiro Nishikawa, Ryohei Kawabata, Tomohira Takeoka, Akihiro Kitagawa, Nobuyoshi Ohara, Hideo Tomihara, Sakae Maeda, Mitsunobu Imazato, Shingo Noura, Atsushi Miyamoto
Publikováno v:
BMC Gastroenterology, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background The increasing incidence of gastric cancer in the elderly underscores the need for an in-depth understanding of the challenges and risks associated with surgical interventions in this demographic. This study aims to investigate th
Externí odkaz:
https://doaj.org/article/04cf37ef1577422f9506a68a561b21b8
Autor:
J. Muriel, M. Escorial, C. Carratalá, C. Margarit, J. Barrachina, A. López, E. Gallardo, MK Kringen, A.M. Peiró
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 176, Iss , Pp 116882- (2024)
Background: Several opioids have pharmacogenetic and drug-drug interactions which may compromise their analgesic effectiveness, but are not routinely implemented into supportive pain management. We hypothesized that CYP2D6 phenotypes and concomitant
Externí odkaz:
https://doaj.org/article/8045cb3151a7441aa193f977aa83c42f
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e31652- (2024)
Self-supply water sources, particularly groundwater sources, play key roles in the water supply ecosystem of developing countries. Recent studies indicate that groundwater sources in coastal communities in Ghana are under threat from improper waste m
Externí odkaz:
https://doaj.org/article/0b145c46538d49da904cf466fa3fd252
Autor:
Mathilde Adsersen, Maiken Bang Hansen, Mette Asbjoern Neergaard, Per Sjøgren, Mai-Britt Guldin, Mogens Groenvold
Publikováno v:
Acta Oncologica, Vol 63, Iss 1 (2024)
Background: Danish Palliative Care Database comprises five quality indicators: (1) Contact with specialised palliative care (SPC) among referred patients, (2) Waiting time of less than 10 days, (3) Proportion of patients who died from (A) cancer or (
Externí odkaz:
https://doaj.org/article/27a656ff31fe449cba3e229fdd7cd2ff
Autor:
Divya Ajmeera, Rajanna Ajumeera
Publikováno v:
Genes and Diseases, Vol 11, Iss 1, Pp 148-175 (2024)
Chemotherapy is an effortless and frequently used approach in cancer therapy. However, in most cases, it can only prolong life expectancy and does not guarantee a complete cure. Furthermore, chemotherapy is associated with severe adverse effects, one
Externí odkaz:
https://doaj.org/article/e112eaef96104ee8a52dbab151aa35cf