Use and persistence of single and multiple inhaler triple therapy prescribed for patients with COPD in France: a retrospective study on THIN database (OPTI study)

Autor: Gaëtan Deslee, Andrew Maguire, Gabriel Thabut, Caroline Fabry-Vendrand, Nolwenn Poccardi, Caroline Eteve Pitsaer, Adrien Coriat, Charlotte Renaudat, Thomas Pinto

Publikováno v: BMJ Open Respiratory Research, Vol 10, Iss 1 (2023)

Introduction From 2018 single inhaler triple therapy (SITT) became available in France to treat moderate-to-severe chronic obstructive pulmonary disease (COPD). Given its simplified inhaler use compared with multiple inhaler triple therapy (MITT), th

Externí odkaz: https://doaj.org/article/f7c4d74960104563a812915b7b0ff40f

Latency Entry of Herpes Simplex Virus 1 Is Determined by the Interaction of Its Genome with the Nuclear Environment.

Autor: Mohamed Ali Maroui, Aleth Callé, Camille Cohen, Nathalie Streichenberger, Pascale Texier, Julie Takissian, Antoine Rousseau, Nolwenn Poccardi, Jérémy Welsch, Armelle Corpet, Laurent Schaeffer, Marc Labetoulle, Patrick Lomonte

Publikováno v: PLoS Pathogens, Vol 12, Iss 9, p e1005834 (2016)

Herpes simplex virus 1 (HSV-1) establishes latency in trigeminal ganglia (TG) sensory neurons of infected individuals. The commitment of infected neurons toward the viral lytic or latent transcriptional program is likely to depend on both viral and c

Externí odkaz: https://doaj.org/article/88d2eebc310548cc973e0fd55e738305

Promyelocytic leukemia (PML) nuclear bodies (NBs) induce latent/quiescent HSV-1 genomes chromatinization through a PML NB/Histone H3.3/H3.3 Chaperone Axis

Autor: Patrick Lomonte, Olivier Binda, Mohamed Ali Maroui, Armelle Corpet, Constance Kleijwegt, Marc Labetoulle, Simon Roubille, Antoine Rousseau, Nolwenn Poccardi, Nancy M. Sawtell, Pascale Texier, Camille Cohen

Publikováno v: PLoS Pathogens
PLoS Pathogens, 2018, 14 (9), pp.e1007313. ⟨10.1371/journal.ppat.1007313⟩
PLoS Pathogens, Public Library of Science, 2018, 14 (9), pp.e1007313. ⟨10.1371/journal.ppat.1007313⟩
PLoS Pathogens, Vol 14, Iss 9, p e1007313 (2018)

Herpes simplex virus 1 (HSV-1) latency establishment is tightly controlled by promyelocytic leukemia (PML) nuclear bodies (NBs) (or ND10), although their exact contribution is still elusive. A hallmark of HSV-1 latency is the interaction between late

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4223afd24d6fa66e40a276d908a0ae5
https://doi.org/10.1371/journal.ppat.1007313

Functional evidence for the involvement of microtubules and dynein motor complexes in TRIM5α-mediated restriction of retroviruses

Autor: Paulina Pawlica, Lionel Berthoux, V. Le Sage, Michel J. Tremblay, Nolwenn Poccardi, Andrew J. Mouland

Publikováno v: Journal of virology. 88(10)

The tripartite motif (TRIM) family of proteins includes the TRIM5α antiretroviral restriction factor. TRIM5α from many Old World and some New World monkeys can restrict the human immunodeficiency virus type 1 (HIV-1), while human TRIM5α restricts

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b278dc20c88eebb53859b1039564f9
https://pubmed.ncbi.nlm.nih.gov/24600008