Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Nolwen Guigal-Stephan"'
Autor:
Sabrina Le Bouter, Marianne Rodriguez, Nolwen Guigal-Stephan, Sophie Courtade-Gaïani, Laura Xuereb, Catherine de Montrion, Vincent Croixmarie, Thierry Umbdenstock, Claire Boursier-Neyret, Michel Lonchampt, Manuel Brun, Catherine Dacquet, Alain Ktorza, Brian-Paul Lockhart, Jean-Pierre Galizzi
Publikováno v:
PPAR Research, Vol 2010 (2010)
Rosiglitazone (RSG), developed for the treatment of type 2 diabetes mellitus, is known to have potent effects on carbohydrate and lipid metabolism leading to the improvement of insulin sensitivity in target tissues. To further assess the capacity of
Externí odkaz:
https://doaj.org/article/46df16f6182e4c53869defeac3035f9f
Autor:
Hélène Salaun, Charlotte Proudhon, Chantal Bourrier, Ellen Heitzer, Laura Xuereb, Michael R. Speicher, Nolwen Guigal-Stephan, Jean-Yves Pierga, Brian Paul Lockhart, Jelena Belic
Publikováno v:
Cancers
Cancers, Vol 12, Iss 1481, p 1481 (2020)
Volume 12
Issue 6
Cancers, Vol 12, Iss 1481, p 1481 (2020)
Volume 12
Issue 6
Background: Focal amplification of fibroblast growth factor receptor 1 (FGFR1) defines a subgroup of breast cancers with poor prognosis and high risk of recurrence. We sought to demonstrate the potential of circulating cell-free DNA (cfDNA) analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a9efe83b4ac36ea964b5756c762566
Autor:
James A. H. Murray, Fabien Melchiore, Natalia Matassova, C. Pedder, Frédéric Colland, Catherine Chang, Levente Ondi, Laura C. A. Galbraith, Pawel Dokurno, Andrew W. Roberts, Chris D. Riffkin, Nolwen Guigal-Stephan, Proszenyák Ágnes, John A. Hickman, Andreas Strasser, Aurélie Studeny, Gaëlle Lysiak-Auvity, András Kotschy, Gemma L. Kelly, Fabienne Gravé, Ghislaine Guasconi, Brandon J. Aubrey, Attila Paczal, Julia Smith, Szlávik Zoltán, Gabor Radics, Brian Lockhart, David C.S. Huang, Maïa Chanrion, Gaëtane Le Toumelin-Braizat, Jia-Nan Gong, Nicolas Cauquil, Szabolcs Sipos, Alan P. Robertson, Giovanna Pomilio, James Edward Paul Davidson, Zoltán B. Szabó, Ana Leticia Maragno, Chris Graham, Marco J Herold, Gábor Blasko, Margs S. Brennan, Anne-Marie Girard, Allan E. Surgenor, Andrew H. Wei, Csékei Márton, Olivier Geneste, Chen I-Jen, Alain Bruno, David J. Segal, Guillaume Lessene, Balázs Bálint, Donia M Moujalled
Publikováno v:
Nature. 538:477-482
Avoidance of apoptosis is critical for the development and sustained growth of tumours. The pro-survival protein myeloid cell leukemia 1 (MCL1) is overexpressed in many cancers, but the development of small molecules targeting this protein that are a
Autor:
Catherine Dacquet, Catherine de Montrion, Sabrina Le Bouter, Michel Lonchampt, Manuel Brun, Claire Boursier-Neyret, Nolwen Guigal-Stephan, Vincent Croixmarie, Brian-Paul Lockhart, Thierry Umbdenstock, Marianne Rodriguez, Sophie Courtade-Gaiani, Laura Xuereb, Jean-Pierre Galizzi, Alain Ktorza
Publikováno v:
PPAR Research, Vol 2010 (2010)
PPAR Research
PPAR Research
Rosiglitazone (RSG), developed for the treatment of type 2 diabetes mellitus, is known to have potent effects on carbohydrate and lipid metabolism leading to the improvement of insulin sensitivity in target tissues. To further assess the capacity of
Autor:
Agnès Chomel, Chantal Bourrier, Pierre Lestage, Laurence Danober, Lockhart Brian, Sophie Courtade-Gaiani, Marianne Rodriguez, Jean-Pierre Galizzi, Nolwen Guigal-Stephan, Sandra Catesson, Nadège Villain, Bernard Pirotte, Fabienne Barbet, Daniel-Henry Caignard, Sophie Mourlevat, Gaëlle Rolland-Valognes
Publikováno v:
Neuroscience research. 70(4)
To improve our understanding of the molecular events underlying the effects of positive allosteric modulators of the alpha-amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid (S)-AMPA-type glutamate receptors, gene expression profiles of primary cort
Autor:
Nolwen Guigal-Stephan, Marianne Rodriguez, Alain Pierre, Jean-Claude Ortuno, Celine Bossard, Mike Burbridge, Carine Saunier, Lockhart Brian, Stéphane Depil, Jean-Pierre Galizzi, Anne Jacquet-Bescond, Francisco Cruzalegui, Alain Bruno, Imre Fejes
Publikováno v:
Cancer Research. 72:848-848
Aberrant activity of receptor tyrosine kinases (RTKs) has been associated with tumor progression in a wide variety of human malignancies, making them promising drug targets for cancer therapy. Although, in some instances, specific inhibition of just
Autor:
Lockhart Brian, Stéphane Depil, Nolwen Guigal-Stephan, Carine Saunier, Francisco Cruzalegui, Mike Burbridge, Celine Bossard, Jean-Pierre Galizzi, Jean-Claude Ortuno, Anne Jacquet-Bescond, Chantal Bourrier, Marianne Rodriguez
Publikováno v:
Molecular Cancer Therapeutics. 10:A240-A240
Protein kinase inhibitors constitute a class of anticancer agents with demonstrated clinical efficacy. However, the clinical benefit of these agents is often limited to a subset of patients with specific genomic lesions in their tumor cells rendering