Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Nollaig Bourke"'
Autor:
Etienne Villain, Aurélie Chanson, Malwina Mainka, Nadja Kampschulte, Pauline Le Faouder, Justine Bertrand-Michel, Marion Brandolini-Bulon, Bruno Charbit, Munyaradzi Musvosvi, Nicole Bilek, Thomas J. Scriba, Lluis Quintana-Murci, Nils Helge Schebb, Darragh Duffy, Cécile Gladine, Laurent Abel, Andres Alcover, Hugues Aschard, Philippe Bousso, Nollaig Bourke, Petter Brodin, Pierre Bruhns, Nadine Cerf-Bensussan, Ana Cumano, Christophe D’Enfert, Ludovic Deriano, Marie-Agnès Dillies, James Di Santo, Gérard Eberl, Jost Enninga, Jacques Fellay, Ivo Gomperts-Boneca, Milena Hasan, Gunilla Karlsson Hedestam, Serge Hercberg, Molly A. Ingersoll, Olivier Lantz, Rose Anne Kenny, Mickaël Ménager, Hugo Mouquet, Cliona O'Farrelly, Etienne Patin, Sandra Pellegrini, Antonio Rausell, Frédéric Rieux-Laucat, Lars Rogge, Magnus Fontes, Anavaj Sakuntabhai, Olivier Schwartz, Benno Schwikowski, Spencer Shorte, Frédéric Tangy, Antoine Toubert, Mathilde Touvier, Marie-Noëlle Ungeheuer, Christophe Zimmer, Matthew L. Albert
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107422- (2023)
Summary: Oxylipins are major immunomodulating mediators, yet studies of inflammation focus mainly on cytokines. Here, using a standardized whole-blood stimulation system, we characterized the oxylipin-driven inflammatory responses to various stimuli
Externí odkaz:
https://doaj.org/article/197340910dcf4806952a46ee824b2e76
Autor:
Eamon Laird, Aisling M O'Halloran, Anne M Molloy, Martin Healy, Nollaig Bourke, Rose Anne Kenny
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0287169 (2023)
Research studies have observed associations of vitamin D with inflammation but data in representative older adult studies is lacking. We aimed to investigate the association of C-reactive protein (CRP) with vitamin D status in a representative sample
Externí odkaz:
https://doaj.org/article/a5900c7a1dd741f5ae13b9419319abe4
Autor:
Celine Posseme, Alba Llibre, Bruno Charbit, Vincent Bondet, Vincent Rouilly, Violaine Saint-André, Jeremy Boussier, Jacob Bergstedt, Nikaïa Smith, Liam Townsend, Jamie A. Sugrue, Clíona Ní Cheallaigh, Niall Conlon, Maxime Rotival, Michael S. Kobor, Estelle Mottez, Stanislas Pol, Etienne Patin, Matthew L. Albert, Lluis Quintana-Murci, Darragh Duffy, Laurent Abel, Andres Alcover, Hugues Aschard, Philippe Bousso, Nollaig Bourke, Petter Brodin, Pierre Bruhns, Nadine Cerf-Bensussan, Ana Cumano, Caroline Demangel, null Christophe d’Enfert, Ludovic Deriano, Marie-Agnès Dillies, James Di Santo, Françoise Dromer, Gérard Eberl, Jost Enninga, Jacques Fellay, Ivo Gomperts-Boneca, Milena Hasan, Magnus Fontes, Gunilla Karlsson Hedestam, Serge Hercberg, Molly A. Ingersoll, Rose Anne Kenny, Olivier Lantz, Mickael Ménager, Frédérique Michel, Hugo Mouquet, Cliona O'Farrelly, Sandra Pellegrini, Antonio Rausell, Frédéric Rieux-Laucat, Lars Rogge, Anavaj Sakuntabhai, Olivier Schwartz, Benno Schwikowski, Spencer Shorte, Frédéric Tangy, Antoine Toubert, Mathilde Touvier, Marie-Noëlle Ungeheuer, Christophe Zimmer
Publikováno v:
Cell Reports
Cell Reports, 2022, 39 (13), pp.110989. ⟨10.1016/j.celrep.2022.110989⟩
Cell Reports, 2022, ⟨10.1016/j.celrep.2022.110989⟩
Cell Reports, 2022, 39 (13), pp.110989. ⟨10.1016/j.celrep.2022.110989⟩
Cell Reports, 2022, ⟨10.1016/j.celrep.2022.110989⟩
International audience; The interleukin-12 (IL-12) family comprises the only heterodimeric cytokines mediating diverse functional effects. We previously reported a striking bimodal IL-12p70 response to lipopolysaccharide (LPS) stimulation in healthy
Autor:
Darragh Duffy, Nikaïa SMITH, Céline Possémé, Vincent Bondet, Jamie Sugrue, Liam Townsend, Bruno Charbit, Vincent Rouilly, Violaine Saint-André, Tom Dott, Andre Rodriguez Pozo, Nader Yatim, Olivier Schwartz, Minerva Cervantes-Gonzales, Jade Ghosn, Paul Bastard, Jean-Laurent Casanova, Tali-Anne Szwebel, Benjamin Terrier, Niall Conlon, Cliona O'Farrelly, Cliona Ni Cheallaigh, Nollaig Bourke
Host immunity to infection with SARS-CoV-2 is highly variable, dictating diverse clinical outcomes ranging from asymptomatic to severe disease and death. We previously reported that reduced blood type I interferon (IFN-I) in severe COVID-19 patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fd88ee806c983974fa9c8cfed8b1570
https://hal-pasteur.archives-ouvertes.fr/pasteur-03699367/file/v1_covered.pdf
https://hal-pasteur.archives-ouvertes.fr/pasteur-03699367/file/v1_covered.pdf
Autor:
Dyer A, Townsend L, Naughton A, Kiersey R, Holden D, Gardiner M, Dunne J, O'Farrelly C, Cheallaigh C, Conlon N, Nollaig Bourke
Publikováno v:
Age and Ageing
Europe PubMed Central
Europe PubMed Central
Background Whilst age and frailty are independently associated with mortality in COVID-19 illness, the underlying immunological mechanisms explaining this remain unexplored. We aimed to explore the impact of age and frailty on the acute immune respon
Autor:
Niamh E. Mangan, Caroline E. Gargett, Nollaig Bourke, Sebastian Stifter, Ka Yee Fung, Paul J. Hertzog
Publikováno v:
Cytokine. 63:284
In the female reproductive tract (FRT), homeostasis needs to be maintained to enable embryo implantation and development in parallel with priming of the immune system, which protects against localised infection. The FRT is at risk from mucosal pathog
Autor:
Dyer A, Noonan C, Pierpoint R, Leonard A, Boran G, Brady G, Fallon A, O'Farrelly C, Nollaig Bourke, Kennelly
Publikováno v:
Europe PubMed Central
Introduction Older nursing home residents are the population at greatest risk of morbidity and mortality from SARS-CoV-2 infection. No studies have examined the determinants of long-term antibody responses post-vaccination in this group. Method Longi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::021eb932c5136056b4448a343f0dde64
http://europepmc.org/abstract/PMC/PMC9384287
http://europepmc.org/abstract/PMC/PMC9384287
Autor:
Bergstedt, Jacob, Azzou, Sadoune Ait Kaci, Tsuo, Kristin, Jaquaniello, Anthony, Urrutia, Alejandra, Rotival, Maxime, Lin, David, Macisaac, Julia, Kobor, Michael, Albert, Matthew, Duffy, Darragh, Patin, Etienne, Quintana-Murci, Lluís, Intérieur Consortium, Milieu
Publikováno v:
Nature Communications
Nature Communications, 2022, 13 (1), pp.5895. ⟨10.1038/s41467-022-33511-6⟩
Nature Communications, 2022, 13 (1), pp.5895. ⟨10.1038/s41467-022-33511-6⟩
Epigenetic changes are required for normal development, yet the nature and respective contribution of factors that drive epigenetic variation in humans remain to be fully characterized. Here, we assessed how the blood DNA methylome of 884 adults is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565efb84a7a5053661b6a2ed5551f9eb
https://hal-pasteur.archives-ouvertes.fr/pasteur-03865045/document
https://hal-pasteur.archives-ouvertes.fr/pasteur-03865045/document
Autor:
Lluis Quintana-Murci, Bruno Charbit, Antonio Rausell, Darragh Duffy, Caron B, Matthew L. Albert, Etienne Patin, Maxime Rotival
Publikováno v:
Genome Medicine
Genome Medicine, 2022, 14 (1), pp.28. ⟨10.1186/s13073-022-01032-y⟩
Genome Medicine, 2022, 14 (1), pp.28. ⟨10.1186/s13073-022-01032-y⟩
Background Blood plasma proteins play an important role in immune defense against pathogens, including cytokine signaling, the complement system, and the acute-phase response. Recent large-scale studies have reported genetic (i.e., protein quantitati