Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Nolan D. Hartley"'
Autor:
Rebecca J. Bluett, Rita Báldi, Andre Haymer, Andrew D. Gaulden, Nolan D. Hartley, Walker P. Parrish, Jordan Baechle, David J. Marcus, Ramzi Mardam-Bey, Brian C. Shonesy, Md. Jashim Uddin, Lawrence J. Marnett, Ken Mackie, Roger J. Colbran, Danny G. Winder, Sachin Patel
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
Understanding inter-individual differences in stress-susceptibility could lead to novel treatments and preventative strategies for stress-related pathologies. Here the authors provide evidence that increased endocannabinoid signalling is a resilience
Externí odkaz:
https://doaj.org/article/dd20f8d48c844ac681502ee88a660e82
Autor:
Chanan D. Sessler, Yiming Zhou, Wenbo Wang, Nolan D. Hartley, Zhanyan Fu, David Graykowski, Morgan Sheng, Xiao Wang, Jia Liu
Publikováno v:
Science Advances. 8
Ionic conductivity and membrane capacitance are two foundational parameters that govern neuron excitability. Conventional optogenetics has emerged as a powerful tool to temporarily manipulate membrane ionic conductivity in intact biological systems.
Autor:
Andrew D. Gaulden, Nolan D. Hartley, Md. Jashim Uddin, Toni A. Patrick, Emily Neale, Philip J. Kingsley, Gaurav Bedse, Niels Plath, Lawrence J. Marnett, Sachin Patel
Publikováno v:
Biological Psychiatry. 82:488-499
Background Increasing the available repertoire of effective treatments for mood and anxiety disorders represents a critical unmet need. Pharmacological augmentation of endogenous cannabinoid (eCB) signaling has been suggested to represent a novel app
Publikováno v:
Journal of Neurochemistry. 143:171-182
Adrenal chromaffin cells (ACCs) are the neuroendocrine arm of the sympathetic nervous system and key mediators of the physiological stress response. Acetylcholine (ACh) released from preganglionic splanchnic nerves activates nicotinic acetylcholine r
Autor:
Ken Mackie, Roger J. Colbran, Walker P. Parrish, Rebecca J. Bluett, Jordan J. Baechle, David J. Marcus, Andrew D. Gaulden, Md. Jashim Uddin, Andre Haymer, Nolan D. Hartley, Brian C. Shonesy, Sachin Patel, Lawrence J. Marnett, Ramzi Mardam-Bey, Danny G. Winder, Rita Báldi
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
Nature Communications
Nature Communications
Stress is a ubiquitous risk factor for the exacerbation and development of affective disorders including major depression and posttraumatic stress disorder. Understanding the neurobiological mechanisms conferring resilience to the adverse consequence
Autor:
Carrie A. Grueter, Maya P. Misra, Rita Báldi, Nolan D. Hartley, Brad A. Grueter, Oakleigh M. Folkes, Sachin Patel, Megan Altemus, David J. Marcus, Brandon D. Turner, Jordan J. Baechle, Veronika Kondev, Jade K. Ayers
Publikováno v:
J Clin Invest
Deficits in social interaction (SI) are a core symptom of autism spectrum disorders (ASDs); however, treatments for social deficits are notably lacking. Elucidating brain circuits and neuromodulatory signaling systems that regulate sociability could
Autor:
Nolan D. Hartley, Andrew D. Gaulden, Danny G. Winder, Alexis Jameson, Nathan D. Winters, Sachin Patel, Rita Báldi, Luis Eduardo Rosas-Vidal, Gregory J. Salimando
Publikováno v:
Nature neuroscience
Acquisition and extinction of learned fear responses utilize conserved but flexible neural circuits. Here we show that acquisition of conditioned freezing behavior is associated with dynamic remodeling of relative excitatory drive from the basolatera
Autor:
Nolan D. Hartley, Daniel J. Hermanson, Joyonna Gamble-George, Jeff Reese, Lawrence J. Marnett, Brian C. Shonesy, Roger J. Colbran, Sachin Patel, Phillip J. Kingsley, Naoko Brown
Publikováno v:
Nature neuroscience
Augmentation of endogenous cannabinoid (eCB) signaling represents an emerging approach to the treatment of affective disorders. Cyclooxygenase-2 (COX-2) oxygenates arachidonic acid to form prostaglandins, but also inactivates eCBs in vitro. However,
Autor:
Nolan D. Hartley, Carolyn Grace Silva, Andre Haymer, Sachin Patel, Lawrence J. Marnett, Joyonna Gamble-George, Andrew Holmes, Rita Báldi, Holly Roberts, Adrina Kocharian, Lindsay R. Halladay
Publikováno v:
eLife
eLife, Vol 5 (2016)
eLife, Vol 5 (2016)
Mood and anxiety disorders are the most prevalent psychiatric conditions and are exacerbated by stress. Recent studies have suggested cyclooxygenase-2 (COX-2) inhibition could represent a novel treatment approach or augmentation strategy for affectiv
Autor:
Nolan D. Hartley, Andre Haymer, Joyonna Gamble-George, Holly Roberts, Lawrence J. Marnett, Carolyn Grace Silva, Sachin Patel, Andrew Holmes, Rita Báldi, Adrina Kocharian, Lindsay R. Halladay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfd96696ee89c57fb754be885f341beb
https://doi.org/10.7554/elife.14137.024
https://doi.org/10.7554/elife.14137.024