Výsledky vyhledávání - "Nolan Chatron"

Akademický článek

Structural Insights into Phylloquinone (Vitamin K1), Menaquinone (MK4, MK7), and Menadione (Vitamin K3) Binding to VKORC1

Autor: Nolan Chatron, Abdessalem Hammed, Etienne Benoît, Virginie Lattard

Publikováno v: Nutrients, Vol 11, Iss 1, p 67 (2019)

Vitamin K family molecules—phylloquinone (K1), menaquinone (K2), and menadione (K3)—act as γ-glutamyl carboxylase (GGCX)-exclusive cofactors in their hydroquinone state, activating proteins of main importance for blood coagulation in the liver a

Externí odkaz: https://doaj.org/article/63f5884466c341b792af6dbf7180b661

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Comparative biological properties of the four stereoisomers of difethialone, a second-generation anticoagulant rodenticide, in rats: development of a model allowing to choose the appropriate stereoisomeric ratio

Autor: Etienne Benoit, Nolan Chatron, Virginie Lattard, Sébastien Lefebvre, Hervé Caruel, Isabelle Fourel

Publikováno v: Archives of Toxicology
Archives of Toxicology, Springer Verlag, 2020, ⟨10.1007/s00204-020-02662-0⟩
Archives of Toxicology, Springer Verlag, 2020, 94 (3), pp.795-801. ⟨10.1007/s00204-020-02662-0⟩

The current management of rodent pest populations is based on second-generation anticoagulant rodenticides (SGAR). These molecules, of which difethialone is part, are much more efficient than the first generation. Nevertheless, this efficiency comes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::433e2ba4abd5c0d15969e80817f163aa
https://doi.org/10.1007/s00204-020-02662-0

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Structural Investigation of the Vitamin K Epoxide Reductase (VKORC1) Binding Site with Vitamin K

Autor: Etienne Benoit, Nolan Chatron, Rami Abi Khalil, Virginie Lattard

Publikováno v: Biochemistry
Biochemistry, American Chemical Society, 2020, 59 (13), pp.1351-1360. ⟨10.1021/acs.biochem.9b01084⟩

International audience; The vitamin K epoxide reductase (VKORC1) enzyme is of primary importance in many physiological processes, i.e., blood coagulation, energy metabolism, and arterial calcification prevention, due to its role in the vitamin K cycl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f96b7f0292acff9ef868e1f6fec6073b
https://hal.inrae.fr/hal-03151932

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Elevated difenacoum metabolism is involved in the difenacoum-resistant phenotype observed in Berkshire rats homozygous for the L120Q mutation in the vitamin K epoxide reductase complex subunit 1 (Vkorc1) gene

Autor: Nolan Chatron, Virginie Lattard, Etienne Benoit, Jean Valéry Debaux, Abdessalem Hammed, Maylis Boitet

Publikováno v: Pest Management Science. 74:1328-1334

BACKGROUND Soon after difenacoum began to be used, resistance to this rodenticide was detected in rats in northeast Hampshire and northwest Berkshire in England. Resistance to difenacoum has been reported to be stronger in rats from Berkshire than in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fc2932395cd4d935a0fedfd4ab98b150
https://doi.org/10.1002/ps.4797

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Structural Insights into Phylloquinone (Vitamin K1), Menaquinone (MK4, MK7), and Menadione (Vitamin K3) Binding to VKORC1

Autor: Abdessalem Hammed, Nolan Chatron, Virginie Lattard, Etienne Benoit

Publikováno v: Nutrients
Volume 11
Issue 1
Nutrients, MDPI, 2019, 11 (1), pp.67. ⟨10.3390/nu11010067⟩
Nutrients, Vol 11, Iss 1, p 67 (2019)
Nutrients 1 (11), . (2019)

Vitamin K family molecules&mdash
phylloquinone (K1), menaquinone (K2), and menadione (K3)&mdash
act as &gamma
glutamyl carboxylase (GGCX)-exclusive cofactors in their hydroquinone state, activating proteins of main importance for blood

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2416744bbe5605373bede2901e7428e

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Evidence of a target resistance to antivitamin K rodenticides in the roof rat Rattus rattus : identification and characterisation of a novel Y25F mutation in the Vkorc1 gene

Autor: Luba Tchertanov, Nolan Chatron, Lionel Legros, Véronique Lambert, Joffrey Goulois, Audrey Chapuzet, Etienne Benoit, Virginie Lattard

Publikováno v: Pest Management Science. 72:544-550

BACKGROUND In spite of intensive use of bromadiolone, rodent control was inefficient on a farm infested by rats in Zaragoza, Spain. While metabolic resistance was previously described in this rodent species, the observation of a target resistance to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::779424c6d4b75099c5d2f4f873e353b7
https://doi.org/10.1002/ps.4020

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Autor: Maylis, Boitet, Abdessalem, Hammed, Nolan, Chatron, Jean Valéry, Debaux, Etienne, Benoit, Virginie, Lattard

Publikováno v: Pest management science. 74(6)

Soon after difenacoum began to be used, resistance to this rodenticide was detected in rats in northeast Hampshire and northwest Berkshire in England. Resistance to difenacoum has been reported to be stronger in rats from Berkshire than in rats from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e8d5c8998fa3b930e7d9cf0ef3ffd90b
https://pubmed.ncbi.nlm.nih.gov/29155484

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Evidence of a target resistance to antivitamin K rodenticides in the roof rat Rattus rattus: identification and characterisation of a novel Y25F mutation in the Vkorc1 gene

Autor: Joffrey, Goulois, Audrey, Chapuzet, Véronique, Lambert, Nolan, Chatron, Luba, Tchertanov, Lionel, Legros, Etienne, Benoît, Virginie, Lattard

Publikováno v: Pest Management Science
Pest Management Science, Wiley, 2016, 72 (3), pp.544-550. ⟨10.1002/ps.4020⟩

International audience; BACKGROUNDIn spite of intensive use of bromadiolone, rodent control was inefficient on a farm infested by rats in Zaragoza, Spain. While metabolic resistance was previously described in this rodent species, the observation of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c33fe78642af16817db18ea463ae273a
https://hal.inrae.fr/hal-02630922

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