Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nohemí Arellano-Sánchez"'
Autor:
Joaquin Teixidó, Nohemí Arellano-Sánchez, Lucía Benito-Jardón, Paloma Vaquero-Morales, Marta Díaz-Martínez, Azucena Esparís-Ogando
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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39 p.-7 fig.
Combined treatment of metastatic melanoma with BRAF and MEK inhibitors has improved survival, but the emergence of resistance represents an important clinical challenge. Targeting ERK is a suitable strategy currently being investiga
Combined treatment of metastatic melanoma with BRAF and MEK inhibitors has improved survival, but the emergence of resistance represents an important clinical challenge. Targeting ERK is a suitable strategy currently being investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea29bbc0734367fe3bb8aa6f55437a46
https://doi.org/10.1158/0008-5472.can-18-2762
https://doi.org/10.1158/0008-5472.can-18-2762
Autor:
Anna Sánchez‐Vencells, Joaquin Martinez-Lopez, Mónica Martínez-Moreno, Antonio Valeri, Consuelo Gajate, Nohemí Arellano-Sánchez, Faustino Mollinedo, Xabier Agirre, Silvia Sevilla-Movilla, Luis Vitores Valcárcel, Felipe Prosper, Joaquin Teixidó
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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instname
36 p.-6 fig.
The interaction of multiple myeloma (MM) cells with the bone marrow (BM) microenvironment promotes MM cell retention, survival and resistance to different anti‐MM agents, including proteasome inhibitors (PIs) such as bortezomib (B
The interaction of multiple myeloma (MM) cells with the bone marrow (BM) microenvironment promotes MM cell retention, survival and resistance to different anti‐MM agents, including proteasome inhibitors (PIs) such as bortezomib (B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1637b4d2675873b376f45e9c53e2afef
http://hdl.handle.net/10261/214009
http://hdl.handle.net/10261/214009
Autor:
Joaquin Teixidó, Nohemí Arellano-Sánchez, Soledad Isern de Val, Silvia Sevilla-Movilla, Carlos Cabañas, Rosa García-Verdugo, Ana Dios-Esponera, David García-Bernal
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Molecular Biology of the Cell
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Molecular Biology of the Cell
Stimulation by chemokines of integrin α4β1-dependent T-lymphocyte adhesion is a crucial step for lymphocyte trafficking. The adaptor Vav1 is required for chemokine-activated T-cell adhesion mediated by α4β1. Conceivably, proteins associating with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f9a317e2b1550359a238295e92d8a60
https://doi.org/10.1091/mbc.e14-07-1246
https://doi.org/10.1091/mbc.e14-07-1246
Autor:
Joaquin Teixidó, Isabel Mérida, Marta Díaz-Martínez, Pedro Torres-Ayuso, Jan Willem Kleinovink, Nohemí Arellano-Sánchez, Rubén Álvaro Bartolomé, Georgina P. Coló
Publikováno v:
Cellular Signalling. 26:2551-2561
Activation of the GTPase RhoA linked to cell invasion can be tightly regulated following Gα13 stimulation. We have used a cellular model displaying Gα13-dependent inhibition of RhoA activation associated with defective cell invasion to the chemokin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad07d58e3debe1ea4a45aced3826294e
https://doi.org/10.1016/j.cellsig.2014.07.008
https://doi.org/10.1016/j.cellsig.2014.07.008
Autor:
Norma C. Gutiérrez, Ana Dios-Esponera, Javier Redondo-Muñoz, David García-Bernal, Elvira Bailón, Raphael Chevre, Mercedes Garayoa, Nohemí Arellano-Sánchez, Andrés Hidalgo, Angeles García-Pardo, Joaquin Teixidó
Publikováno v:
The Journal of Pathology. 229:36-48
Myeloma cell adhesion dependent on α4β1 integrin is crucial for the progression of multiple myeloma (MM). The α4β1-dependent myeloma cell adhesion is up-regulated by the chemokine CXCL12, and pharmacological blockade of the CXCL12 receptor CXCR4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d4c2ba24a18fdc50f702ee4071b7005
https://doi.org/10.1002/path.4066
https://doi.org/10.1002/path.4066
Autor:
Pablo Hernández-Varas, John G. Lock, Nohemí Arellano-Sánchez, Joaquin Teixidó, Staffan Strömblad, Rubén Álvaro Bartolomé, Georgina P. Coló
Publikováno v:
Journal of Cell Science; Vol 125
Digital.CSIC. Repositorio Institucional del CSIC
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Digital.CSIC. Repositorio Institucional del CSIC
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Cell migration and invasion require regulated turnover of integrin-dependent adhesion complexes. Rap1-GTP-interacting adaptor molecule (RIAM) is an adaptor protein that mediates talin recruitment to the cell membrane, and whose depletion leads to def
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add4b9d3eef5eea26279265667bcd6aa
https://pubmed.ncbi.nlm.nih.gov/22946047
https://pubmed.ncbi.nlm.nih.gov/22946047
Autor:
David, García-Bernal, Javier, Redondo-Muñoz, Ana, Dios-Esponera, Raphaël, Chèvre, Elvira, Bailón, Mercedes, Garayoa, Nohemí, Arellano-Sánchez, Norma C, Gutierrez, Andrés, Hidalgo, Angeles, García-Pardo, Joaquin, Teixidó
Publikováno v:
The Journal of pathology. 229(1)
Myeloma cell adhesion dependent on α4β1 integrin is crucial for the progression of multiple myeloma (MM). The α4β1-dependent myeloma cell adhesion is up-regulated by the chemokine CXCL12, and pharmacological blockade of the CXCL12 receptor CXCR4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ad39b6dc74ff5a07a0f47cd894339e7a
https://pubmed.ncbi.nlm.nih.gov/22711564
https://pubmed.ncbi.nlm.nih.gov/22711564
Autor:
Joaquin Teixidó, Nohemí Arellano-Sánchez, David García-Bernal, Elena Sotillo-Mallo, Rosa García-Verdugo, Ana Dios-Esponera
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
9 páginas, 6 figuras -- PAGS nros. 1264-1272
Chemokines rapidly and transiently upregulate α4β1 and αLβ2 integrin-mediated adhesion during T lymphocyte extravasation by activating Gα-dependent inside-out signaling. To limit and terminate G
Chemokines rapidly and transiently upregulate α4β1 and αLβ2 integrin-mediated adhesion during T lymphocyte extravasation by activating Gα-dependent inside-out signaling. To limit and terminate G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53185a9b7db60ff40c4ec80cd0424792
https://pubmed.ncbi.nlm.nih.gov/26902301
https://pubmed.ncbi.nlm.nih.gov/26902301
Rap1-GTP-interacting Adaptor Molecule (RIAM) Protein Controls Invasion and Growth of Melanoma Cells*
Autor:
Paloma Sánchez-Mateos, Nohemí Arellano-Sánchez, Vassiliki A. Boussiotis, Andrew Paterson, Iria Medraño-Fernandez, Pablo Hernández-Varas, Staffan Strömblad, Georgina P. Coló, Esther M. Lafuente, Rubén Álvaro Bartolomé, Carlos Cabañas, Joaquin Teixidó
Publikováno v:
Journal of Biological Chemistry; Vol 286
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
The Mig-10/RIAM/lamellipodin (MRL) family member Rap1-GTP-interacting adaptor molecule (RIAM) interacts with active Rap1, a small GTPase that is frequently activated in tumors such as melanoma and prostate cancer. We show here that RIAM is expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::076e65c3f8fcc867ef179bed4b184af9
https://europepmc.org/articles/PMC3099666/
https://europepmc.org/articles/PMC3099666/
Autor:
Ismael Buño, Magdalena Leiva, José A. García-Marco, Norma C. Gutiérrez, Joaquin Martinez-Lopez, P Sánchez-Mateos, Nohemí Arellano-Sánchez, Joaquin Teixidó, Mónica Martínez-Moreno, Angeles García-Pardo, S Isern de Val, Silvia Sevilla-Movilla, R Maldonado, Noemí Aguilera-Montilla, Andrés Hidalgo
Publikováno v:
Europe PubMed Central
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
40 p.-7 fig. Martínez-Moreno, Mónica et al.
Multiple myeloma (MM) and chronic lymphocytic leukemia (CLL) cells must attach to the bone marrow (BM) microvasculature before lodging in the BM microenvironment. Using intravital microscopy (IVM) of
Multiple myeloma (MM) and chronic lymphocytic leukemia (CLL) cells must attach to the bone marrow (BM) microvasculature before lodging in the BM microenvironment. Using intravital microscopy (IVM) of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c59c80a50c46cce7209dad39133b5683
http://europepmc.org/abstract/med/26658839
http://europepmc.org/abstract/med/26658839