Fircifret Logaritmetabel med Nøgle L. Pedersen

Publikováno v: Nyt tidsskrift for matematik, 1905 Jan 01. 16, 82-82.

Externí odkaz: https://www.jstor.org/stable/24528474

Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1 H -Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson's Disease.

Autor: Candito DA; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Simov V; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Gulati A; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Kattar S; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Chau RW; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Lapointe BT; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Methot JL; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., DeMong DE; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Graham TH; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Kurukulasuriya R; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Keylor MH; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Tong L; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey07033, United States., Morriello GJ; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey07033, United States., Acton JJ; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey07033, United States., Pio B; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey07033, United States., Liu W; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey07033, United States., Scott JD; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey07033, United States., Ardolino MJ; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Martinot TA; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Maddess ML; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Yan X; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Gunaydin H; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Palte RL; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., McMinn SE; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Nogle L; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Yu H; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Minnihan EC; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Lesburg CA; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Liu P; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Su J; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey07033, United States., Hegde LG; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Moy LY; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Woodhouse JD; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Faltus R; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Xiong T; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Ciaccio P; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Piesvaux JA; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Otte KM; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Kennedy ME; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Bennett DJ; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., DiMauro EF; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Fell MJ; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Neelamkavil S; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey07033, United States., Wood HB; Merck & Co., Inc., 2015 Galloping Hill Road, Kenilworth, New Jersey07033, United States., Fuller PH; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States., Ellis JM; Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts02115, United States.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2022 Dec 22; Vol. 65 (24), pp. 16801-16817. Date of Electronic Publication: 2022 Dec 07.

Comprehensive Strategies to Bicyclic Prolines: Applications in the Synthesis of Potent Arginase Inhibitors.

Autor: Li D; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Zhang H; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Lyons TW; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Lu M; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Achab A; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Pu Q; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Childers M; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Mitcheltree MJ; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Wang J; IDSU, WuXi AppTec Co., Ltd., Shanghai 200131, China., Martinot TA; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., McMinn SE; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Sloman DL; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Palani A; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Beard A; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Nogle L; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Gathiaka S; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Saurí J; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Kim HY; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Adpressa D; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Spacciapoli P; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Miller JR; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Palte RL; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Lesburg CA; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Cumming J; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States., Fischer C; Department of Discovery Chemistry, Department of Discovery Process Chemistry, Department of In Vitro Pharmacology, Department of Computational and Structural Chemistry, and Department of Analytical Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States.

Publikováno v: ACS medicinal chemistry letters [ACS Med Chem Lett] 2021 Oct 13; Vol. 12 (11), pp. 1678-1688. Date of Electronic Publication: 2021 Oct 13 (Print Publication: 2021).

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.