Zobrazeno 1 - 10 of 22 pro vyhledávání: '"Noga Gershoni Emek"'
1
Akademický článek
Neuroprotection of retinal ganglion cells by the sigma-1 receptor agonist pridopidine in models of experimental glaucoma
Autor: Michal Geva, Noga Gershoni-Emek, Luana Naia, Philip Ly, Sandra Mota, Ana Cristina Rego, Michael R. Hayden, Leonard A. Levin
Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Optic neuropathies such as glaucoma are characterized by retinal ganglion cell (RGC) degeneration and death. The sigma-1 receptor (S1R) is an attractive target for treating optic neuropathies as it is highly expressed in RGCs, and its absenc
Externí odkaz: https://doaj.org/article/ca78b753223b4e7397379916ee16da40
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2
Akademický článek
Pridopidine rescues BDNF/TrkB trafficking dynamics and synapse homeostasis in a Huntington disease brain-on-a-chip model
Autor: Sophie Lenoir, Romane A. Lahaye, Hélène Vitet, Chiara Scaramuzzino, Amandine Virlogeux, Laetitia Capellano, Aurélie Genoux, Noga Gershoni-Emek, Michal Geva, Michael R. Hayden, Frédéric Saudou
Publikováno v: Neurobiology of Disease, Vol 173, Iss , Pp 105857- (2022)
Huntington disease (HD) is a neurodegenerative disorder caused by polyglutamine-encoding CAG repeat expansion in the huntingtin (HTT) gene. HTT is involved in the axonal transport of vesicles containing brain-derived neurotrophic factor (BDNF). In HD
Externí odkaz: https://doaj.org/article/fd15b7293989424cb83b9058a66155a8
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3
Akademický článek
Localization of RNAi Machinery to Axonal Branch Points and Growth Cones Is Facilitated by Mitochondria and Is Disrupted in ALS
Autor: Noga Gershoni-Emek, Topaz Altman, Ariel Ionescu, Christopher J. Costa, Tal Gradus-Pery, Dianna E. Willis, Eran Perlson
Publikováno v: Frontiers in Molecular Neuroscience, Vol 11 (2018)
Local protein synthesis in neuronal axons plays an important role in essential spatiotemporal signaling processes; however, the molecular basis for the post-transcriptional regulation controlling this process in axons is still not fully understood. H
Externí odkaz: https://doaj.org/article/2bb6ee217fce4e6d929ac1aeba9e33c6
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7
Pridopidine rescues BDNF/TrkB trafficking dynamics and synapse homeostasis in a Huntington disease brain-on-a-chip model
Autor: Sophie Lenoir, Romane A. Lahaye, Hélène Vitet, Chiara Scaramuzzino, Amandine Virlogeux, Laetitia Capellano, Aurélie Genoux, Noga Gershoni-Emek, Michal Geva, Michael R. Hayden, Frédéric Saudou
Publikováno v: Neurobiology of disease. 173
Huntington disease (HD) is a neurodegenerative disorder caused by polyglutamine-encoding CAG repeat expansion in the huntingtin (HTT) gene. HTT is involved in the axonal transport of vesicles containing brain-derived neurotrophic factor (BDNF). In HD
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de2ca6386b12235107df1575831d23fc
https://pubmed.ncbi.nlm.nih.gov/36075537
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8
Neuroprotection of retinal ganglion cells by the sigma-1 receptor agonist pridopidine in models of experimental glaucoma
Autor: Ana Cristina Rego, Philip T. T. Ly, Noga Gershoni-Emek, Leonard A. Levin, Luana Naia, Sandra I. Mota, Michael R. Hayden, Michal Geva
Publikováno v: Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Optic neuropathies such as glaucoma are characterized by retinal ganglion cell (RGC) degeneration and death. The sigma-1 receptor (S1R) is an attractive target for treating optic neuropathies as it is highly expressed in RGCs, and its absence causes
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17fbaa1641b4fc0aca8c1421678d599b
http://europepmc.org/articles/PMC8578336
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