Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Noga Bloushtain"'
Autor:
Lina Ding, Ying Su, Anne Fassl, Kunihiko Hinohara, Xintao Qiu, Nicholas W. Harper, Sung Jin Huh, Noga Bloushtain-Qimron, Bojana Jovanović, Muhammad Ekram, Xiaoyuan Zi, William C. Hines, Maša Alečković, Carlos Gil del Alcazar, Ryan J. Caulfield, Dennis M. Bonal, Quang-De Nguyen, Vanessa F. Merino, Sibgat Choudhury, Gabrielle Ethington, Laura Panos, Michael Grant, William Herlihy, Alfred Au, Gedge D. Rosson, Pedram Argani, Andrea L. Richardson, Deborah Dillon, D. Craig Allred, Kirsten Babski, Elizabeth Min Hui Kim, Charles H. McDonnell, Jon Wagner, Ron Rowberry, Kristie Bobolis, Celina G. Kleer, E. Shelley Hwang, Joanne L. Blum, Simona Cristea, Piotr Sicinski, Rong Fan, Henry W. Long, Saraswati Sukumar, So Yeon Park, Judy E. Garber, Mina Bissell, Jun Yao, Kornelia Polyak
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Myoepithelial cells prevent tumour growth and invasion in DCIS. Here, the authors show that p63 and TCF7 cooperate to regulate a transcription factor network for the maintenance of normal myoepithelial function and altered expression of these genes p
Externí odkaz:
https://doaj.org/article/784cf49197cf4d50824d3974f6c39d75
Autor:
Ying Su, Ashim Subedee, Noga Bloushtain-Qimron, Virginia Savova, Marcin Krzystanek, Lewyn Li, Andriy Marusyk, Doris P. Tabassum, Alexander Zak, Mary Jo Flacker, Mei Li, Jessica J. Lin, Saraswati Sukumar, Hiromu Suzuki, Henry Long, Zoltan Szallasi, Alexander Gimelbrant, Reo Maruyama, Kornelia Polyak
Publikováno v:
Cell Reports, Vol 11, Iss 10, Pp 1549-1563 (2015)
Basal-like and luminal breast tumors have distinct clinical behavior and molecular profiles, yet the underlying mechanisms are poorly defined. To interrogate processes that determine these distinct phenotypes and their inheritance pattern, we generat
Externí odkaz:
https://doaj.org/article/6f15bf7525f7429da61f9bca90408f78
Autor:
Kornelia Polyak, Ian E. Krop, Stuart J. Schnitt, Rebecca Gelman, Pedram Argani, Michael S. Sabel, Laura C. Collins, Stine-Kathrein Kraeft, Jun Yao, Min Hu, Daniel Carrasco, Yu-Hui Chen, Noga Bloushtain-Qimron, Celina G. Kleer
Purpose: To evaluate the expression of cathepsin K (CTSK) and CXCL14 in stromal and epithelial cells in human breast tumor progression.Experimental Design: We did immunohistochemical analyses of CTSK and CXCL14 expression in normal breast tissue, bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d96cd5857aac7970ef7ef6d55fe9a40
https://doi.org/10.1158/1078-0432.c.6516780.v1
https://doi.org/10.1158/1078-0432.c.6516780.v1
Autor:
Kornelia Polyak, Ian E. Krop, Stuart J. Schnitt, Rebecca Gelman, Pedram Argani, Michael S. Sabel, Laura C. Collins, Stine-Kathrein Kraeft, Jun Yao, Min Hu, Daniel Carrasco, Yu-Hui Chen, Noga Bloushtain-Qimron, Celina G. Kleer
Supplementary Data from Epithelial and Stromal Cathepsin K and CXCL14 Expression in Breast Tumor Progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e5cbd25dae2ecb057f46b659a1f69b1
https://doi.org/10.1158/1078-0432.22439286
https://doi.org/10.1158/1078-0432.22439286
Autor:
Dennis M. Bonal, Nicholas W. Harper, Judy Garber, Maša Alečković, Kunihiko Hinohara, Carlos R. Gil Del Alcazar, Ron Rowberry, Vanessa F. Merino, Xintao Qiu, Celina G. Kleer, Mina J. Bissell, Henry W. Long, Ying Su, Pedram Argani, William Herlihy, Michael Grant, Gabrielle Ethington, Noga Bloushtain-Qimron, Joanne L. Blum, Muhammad B. Ekram, Laura Panos, Sibgat Choudhury, Saraswati Sukumar, Jon Wagner, Gedge D. Rosson, So Yeon Park, Kirsten Babski, William C. Hines, Quang-Dé Nguyen, Sung Jin Huh, Piotr Sicinski, Deborah A. Dillon, Simona Cristea, Anne Fassl, D. Craig Allred, Rong Fan, Lina Ding, Kristie Bobolis, Elizabeth Min Hui Kim, Bojana Jovanovic, Xiaoyuan Zi, Alfred Au, Charles H. McDonnell, Jun Yao, E. Shelley Hwang, Andrea L. Richardson, Kornelia Polyak, Ryan J. Caulfield
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature communications, vol 10, iss 1
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature communications, vol 10, iss 1
Myoepithelial cells play key roles in normal mammary gland development and in limiting pre-invasive to invasive breast tumor progression, yet their differentiation and perturbation in ductal carcinoma in situ (DCIS) are poorly understood. Here, we in
Autor:
Virginia Savova, Reo Maruyama, Henry W. Long, Mei Li, Lewyn Li, Hiromu Suzuki, Jessica J. Lin, Kornelia Polyak, Andriy Marusyk, Noga Bloushtain-Qimron, Alexander Zak, Ying Su, Alexander A. Gimelbrant, Mary Jo Flacker, Doris P. Tabassum, Ashim Subedee, Saraswati Sukumar, Marcin Krzystanek, Zoltan Szallasi
Publikováno v:
Su, Y, Subedee, A, Bloushtain-Qimron, N, Savova, V, Krzystanek, M, Li, L, Marusyk, A, Tabassum, D P, Zak, A & Szallasi, Z I 2015, ' Somatic Cell Fusions Reveal Extensive Heterogeneity in Basal-like Breast Cancer ', Cell Reports, vol. 11, no. 10, pp. 1549-1563 . https://doi.org/10.1016/j.celrep.2015.05.011
Cell Reports, Vol 11, Iss 10, Pp 1549-1563 (2015)
Cell Reports, Vol 11, Iss 10, Pp 1549-1563 (2015)
Basal-like and luminal breast tumors have distinct clinical behavior and molecular profiles, yet the underlying mechanisms are poorly defined. To interrogate processes that determine these distinct phenotypes and their inheritance pattern, we generat
Autor:
Geert Trooskens, Renske D.M. Steenbergen, Peter J.F. Snijders, Maté Ongenaert, Suzanne Snellenberg, Wim Van Criekinge, Chris J.L.M. Meijer, Kornelia Polyak, Noga Bloushtain-Qimron, Deeksha Pandey, Wendy F van der Meide
Publikováno v:
The Journal of Pathology. 231:53-62
Transformation of epithelial cells by high-risk human papillomavirus (hrHPV) types can lead to anogenital carcinomas, particularly cervical cancer, and oropharyngeal cancers. This process is associated with DNA methylation alterations, often affectin
Autor:
Marianna Lev, Gil Katz, Tal I. Arnon, Aviva Joseph, Niva Lieberman, Eli Kedar, Noga Bloushtain, Ofer Mandelboim, Hagit Achdout, Angel Porgador, Tsufit Gonen-Gross, Ahuva Bar-Ilan, Roi Gazit
The destruction of viral-infected and tumor cells is mediated in part via the lysis receptor of natural killer (NK) cells, NKp46. The nature, however, of its lysis ligands expressed on target cells is poorly defined. Recently, we have identified a no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::276953003cb457cf1497a262fcc0dd6c
https://doi.org/10.1182/blood-2003-05-1716
https://doi.org/10.1182/blood-2003-05-1716
Autor:
William C. Hahn, Jessica J. Kim, So Young Kim, David E. Root, Andrea L. Richardson, Hee Eun Lee, So Yeon Park, Yuri Nikolsky, Zhenhua Wu, Sibgat Choudhury, X. Shirley Liu, Laura Mulvey, Serena J. Silver, Tatiana Nikolskaya, Mithat Gonen, Marina Bessarabova, Karen S. Anderson, Andriy Marusyk, Reo Maruyama, Vanessa Almendro, David A. Frank, Noga Bloushtain-Qimron, Janina Schemme, Sung Jin Huh, Sarah R. Walker, Lauren L. C. Marotta, Kornelia Polyak, Michail Shipitsin
Publikováno v:
Journal of Clinical Investigation. 121:2723-2735
Intratumor heterogeneity is a major clinical problem because tumor cell subtypes display variable sensitivity to therapeutics and may play different roles in progression. We previously characterized 2 cell populations in human breast tumors with dist
Autor:
Sibgat Choudhury, Ying Su, Noga Bloushtain-Qimron, Kornelia Polyak, Muhammad B. Ekram, Sung Jin Huh, Jun Yao, William C. Hines, Lina Ding, Mina J. Bissell
Publikováno v:
Molecular Cancer Research. 16:B62-B62
The normal mammary gland is composed of multiple cell types, including luminal and myoepithelial cells. Myoepithelial cells have also been referred to as natural tumor suppressors due to their inhibitory effect on various neoplastic phenotypes, inclu