Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Noga Alagem"'
Publikováno v:
COPD, Vol 20, Iss 1, Pp 292-297 (2023)
During the COVID-19 pandemic the number of hospital admissions due to chronic obstructive pulmonary disease (COPD) exacerbations was significantly reduced. The reason for this decline is not fully understood. Governmental non-pharmaceutical intervent
Externí odkaz:
https://doaj.org/article/f9b2ebb2ddb146d3be63a34841d35e30
Autor:
Yasmin Maor, Eilat Shinar, Marina Izak, Galia Rahav, Tal Brosh-Nissimov, Asa Kessler, Naomi Rahimi-Levene, Odeda Benin-Goren, Dani Cohen, Iris Zohar, Noga Alagem, Sharon Castro, Oren Zimhony
Publikováno v:
Clinical Infectious Diseases.
Background It is unknown whether convalescent immunoglobulins (cIgG) are better than convalescent plasma (CP) for COVID-19 patients. Methods In this randomized trial we assigned high risk COVID-19 with ≤10 days of symptoms, to receive cIgG or CP. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae67129a383e7bdde8b7f5a364fe5925
https://doi.org/10.1093/cid/ciad305
https://doi.org/10.1093/cid/ciad305
Autor:
Felix Ritzmann, Praneeth Chitirala, Nadine Krüger, Markus Hoffmann, Wei Zuo, Frank Lammert, Sigrun Smola, Naveh Tov, Noga Alagem, Philipp M. Lepper, Stefan Pöhlmann, Christoph Beisswenger, Christian Herr, Robert Bals, Yiwen Yao, Nastasja Seiwert, Guy Danziger
Publikováno v:
American Journal of Respiratory and Critical Care Medicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bf91cfed4907eef479a171294ae2756
https://pubmed.ncbi.nlm.nih.gov/33961754
https://pubmed.ncbi.nlm.nih.gov/33961754
Autor:
Stefan Poehlmann, Christoph Beisswenger, Guy Danziger, Markus Hoffmann, Martina Seibert, Nastasja Seiwert, Sabrina Hoersch, Christian Herr, Noga Alagem, Yiwen Yao, Nadine Krueger, Katharina Guenther, Felix Ritzmann, Praneeth Chitirala, Philipp M. Lepper, Frank Lammert, Wei Zuo, Robert Bals, Sigrun Smola, Bahareh Mozafari, Naveh Tov, Thomas Volk
RationaleThe treatment options for COVID-19 patients are sparse and do not show sufficient efficacy. Alpha-1-antitrypsin (AAT) is a multi-functional host-defense protein with anti-proteolytic and anti-inflammatory activities.ObjectivesThe aim of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7405c9aec8c2cccc21e49c795396342d
https://doi.org/10.1101/2021.04.02.21252580
https://doi.org/10.1101/2021.04.02.21252580
Publikováno v:
Nature Reviews Neurology. 5:598-609
Primary dystonia is characterized by involuntary twisting and turning movements that occur in the absence of overt brain lesions or evidence of neurodegeneration. As Tanabe et al. discuss in this article, advances in structural and functional imaging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0933aa057748d82f749a6668905f560
https://doi.org/10.1038/nrneurol.2009.160
https://doi.org/10.1038/nrneurol.2009.160
Publikováno v:
Neuron. 39:9-12
G protein-coupled inwardly rectifying potassium channels (GIRK/Kir3) are important elements in controlling cellular excitability. In recent years, tremendous progress has been made toward understanding various components involved in channel activatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cce90bb25d1db67d2d3eabbc67708688
https://doi.org/10.1016/s0896-6273(03)00402-1
https://doi.org/10.1016/s0896-6273(03)00402-1
Publikováno v:
Proceedings of the National Academy of Sciences. 99:10783-10788
G protein coupled inwardly rectifying K + channels (GIRK/Kir3.x) are mainly activated by a direct interaction with Gβγ subunits, released upon the activation of inhibitory neurotransmitter receptors. Although Gβγ binding domains on all four subun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be74a56a04ec9c5a10107e1907a8815f
https://doi.org/10.1073/pnas.162346199
https://doi.org/10.1073/pnas.162346199
Tethered protein display identifies a novel Kir3.2 (GIRK2) regulator from protein scaffold libraries
Autor:
Eitan Reuveny, Daniel L. Minor, Kimberly A. Clark, Sviatoslav N. Bagriantsev, Franck C. Chatelain, Noga Alagem
Publikováno v:
ACS Chemical Neuroscience
ACS Chemical Neuroscience, American Chemical Society (ACS), 2014, 5 (9), pp.812-822. ⟨10.1021/cn5000698⟩
ACS Chemical Neuroscience, American Chemical Society (ACS), 2014, 5 (9), pp.812-822. ⟨10.1021/cn5000698⟩
Use of randomized peptide libraries to evolve molecules with new functions provides a means for developing novel regulators of protein activity. Despite the demonstrated power of such approaches for soluble targets, application of this strategy to me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45f9a639c3565c824d6827553c8e2e3e
https://pubmed.ncbi.nlm.nih.gov/25028803
https://pubmed.ncbi.nlm.nih.gov/25028803
Publikováno v:
The Journal of Physiology. 534:381-393
The block of the IRK1/Kir2.1 inwardly rectifying K+ channel by a Ba2+ ion is highly voltage dependent, where the ion binds approximately half-way within the membrane electrical field. The mechanism by which two distinct mutations, E125N and T141A, af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b0a674359b56cfc56f0c34a06108e1
https://doi.org/10.1111/j.1469-7793.2001.00381.x
https://doi.org/10.1111/j.1469-7793.2001.00381.x
Publikováno v:
Neuron
Neuron, Elsevier, 2005, 47 (6), pp.833-843. ⟨10.1016/j.neuron.2005.08.022⟩
Neuron, Elsevier, 2005, 47 (6), pp.833-843. ⟨10.1016/j.neuron.2005.08.022⟩
SummaryIon channels lower the energetic barrier for ion passage across cell membranes and enable the generation of bioelectricity. Electrostatic interactions between permeant ions and channel pore helix dipoles have been proposed as a general mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75afc08c2636978604ef134e57f86377
https://pubmed.ncbi.nlm.nih.gov/16157271
https://pubmed.ncbi.nlm.nih.gov/16157271