Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nofit Borenstein-Auerbach"'
Autor:
Yarden Moalem, Rodolfo Katz, Anand G. Subramaniam, Yehonathan Malis, Yakey Yaffe, Nofit Borenstein-Auerbach, Keshet Tadmor, Roey Raved, Ben M. Maoz, Ji Seung Yoo, Yaniv Lustig, Chen Luxenburg, Eran Perlson, Shirit Einav, Ella H. Sklan
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
Sandfly-borne Toscana virus (TOSV) is an enveloped tri-segmented negative single-strand RNA Phlebovirus. It is an emerging virus predominantly endemic in southwestern Europe and Northern Africa. Although TOSV infection is typically asymptomatic or re
Externí odkaz:
https://doaj.org/article/8d335aa4b957434b93d1762152fac7f9
Autor:
Yi-Heng Hao, M. Carmen Lafita-Navarro, Lauren Zacharias, Nofit Borenstein-Auerbach, Min Kim, Spencer Barnes, Jiwoong Kim, Jerry Shay, Ralph J. DeBerardinis, Maralice Conacci-Sorrell
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-16 (2019)
Abstract Background While regulated WNT activity is required for normal development and stem cell maintenance, mutations that lead to constitutive activation of the WNT pathway cause cellular transformation and drive colorectal cancer. Activation of
Externí odkaz:
https://doaj.org/article/5081501d3fc849a5b04c2db8cc20d343
Autor:
Jonathan Braverman, Min Kim, Thomas Brabletz, Ömer H. Yilmaz, Lizbeth Perez-Castro, Nofit Borenstein-Auerbach, Nicholas P. Lesner, Jessica A. Kilgore, Ralph J. DeBerardinis, Maralice Conacci-Sorrell, Yi Heng Hao, Niranjan Venkateswaran, Prashant Mishra, M. Carmen Lafita-Navarro, Noelle S. Williams, Jerry W. Shay
Publikováno v:
Cell Stress
Tumors display increased uptake and processing of nutrients to fulfill the demands of rapidly proliferating cancer cells. Seminal studies have shown that the proto-oncogene MYC promotes metabolic reprogramming by altering glutamine uptake and metabol
Autor:
Shani Blanga-Kanfi, Assaf Ganoth, Ekaterina Lazdon, Limor Landsman, Dan Frenkel, Yossi Tsfadia, Guy Goldsmith, Lina Sakhneny, Hilit Levy-Barazany, Yuval Nash, Nofit Borenstein-Auerbach, Adi Kopelevich, Tali Benromano, Raphael Alhadeff, Katia Pozyuchenko
Publikováno v:
The FASEB Journal. 35
Inhibition of insulin-degrading enzyme (IDE) is a possible target for treating diabetes. However, it has not yet evolved into a medical intervention, mainly because most developed inhibitors target the zinc in IDE's catalytic site, potentially causin
Autor:
Roshni Ray, Yi Heng Hao, Niranjan Venkateswaran, Maralice Conacci-Sorrell, Nofit Borenstein-Auerbach, Thomas Brabletz, Pier Paolo Scaglioni, Jerry W. Shay, Min Kim, M. Carmen Lafita-Navarro
Publikováno v:
Genes & Development. 32:1303-1308
MYC enhances protein synthesis by regulating genes involved in ribosome biogenesis and protein translation. Here, we show that MYC-induced protein translation is mediated by the transcription factor aryl hydrocarbon receptor (AHR), which is induced b
Autor:
Hao, Yi-Heng, M. Lafita-Navarro, Zacharias, Lauren, Nofit Borenstein-Auerbach, Kim, Min, Barnes, Spencer, Jiwoong Kim, Shay, Jerry, DeBerardinis, Ralph, Maralice Conacci-Sorrell
Additional file 1: Figure S1. (A) Major groups of genes in the WNT pathway are regulated by MYC. Red color represents activated genes, blue repressed genes and purple represents families of genes that contain members repressed and activated by MYC. (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f898a781525ce23d02cbf59f8963dd8
Autor:
Minna Roh-Johnson, Thomas Brabletz, Sarah Anderson, Kumud R. Poudel, Ming Yu, Maralice Conacci-Sorrell, Robert N. Eisenman, Cecilia B. Moens, Jihong Bai, Nofit Borenstein-Auerbach, William N. Grady
Publikováno v:
Proceedings of the National Academy of Sciences. 113
MYC-nick is a cytoplasmic, transcriptionally inactive member of the MYC oncoprotein family, generated by a proteolytic cleavage of full-length MYC. MYC-nick promotes migration and survival of cells in response to chemotherapeutic agents or withdrawal
Autor:
Morihito Takita, Bashoo Naziruddin, Mazhar A. Kanak, Nofit Borenstein-Auerbach, Michael C. Lawrence, Marlon F. Levy, Kathleen McGlynn, Ilham Syed, Faisal Kunnathodi, Rauf Shahbazov
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 29(2)
Nuclear factor of activated T cells (NFAT) is activated by calcineurin in response to calcium signals derived by metabolic and inflammatory stress to regulate genes in pancreatic islets. Here, we show that NFAT targets MAPKs, histone acetyltransferas