Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nofar Torika"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
The renin-angiotensin system (RAS) is an important peripheral system involved in homeostasis modulation, with angiotensin II (Ang II) serving as the main effector hormone. The main enzyme involved in Ang II formation is angiotensin-converting enzyme
Externí odkaz:
https://doaj.org/article/90e2736161fb4d8e8c701493860cc271
Publikováno v:
Frontiers in Endocrinology, Vol 8 (2017)
The importance of brain inflammation to Alzheimer’s disease (AD) pathogenesis has been accepted of late, with it currently being held that brain inflammation aggravates AD pathology. One important aspect of brain inflammation is the recruitment and
Externí odkaz:
https://doaj.org/article/f043c50f3fcc4c4c8b5feb81ee077a4e
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155823 (2016)
The circulating renin-angiotensin system (RAS), including the biologically active angiotensin II, is a fundamental regulatory mechanism of blood pressure conserved through evolution. Angiotensin II components of the RAS have also been identified in t
Externí odkaz:
https://doaj.org/article/3298cd7eb266446cb5ed150287e73029
Publikováno v:
CNS Neuroscience & Therapeutics. 24:231-242
Aims Alzheimer's disease (AD) pathology is associated with brain inflammation involving microglia and astrocytes. The renin-angiotensin system contributes to brain inflammation associated with AD pathology. This study aimed to investigate the role of
Publikováno v:
Journal of Neuroimmune Pharmacology. 11:774-785
Angiotensin converting enzyme (ACE) converts Angiotensin I to a potent vasoconstrictor angiotensin II (ANG II). ACE inhibitors (ACEIs) are widely used for the management of hypertension. All components of the renin-angiotensin system (RAS) have also
Publikováno v:
Biological Chemistry. 397:345-351
An Increasing body of evidence supports a critical role of brain inflammation in the pathogenesis of Alzheimer’s disease. A principal aspect of the brain immune response to inflammation is the activation of microglia. It has been shown that the kin
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience
The renin-angiotensin system (RAS) is an important peripheral system involved in homeostasis modulation, with angiotensin II (Ang II) serving as the main effector hormone. The main enzyme involved in Ang II formation is angiotensin-converting enzyme
Publikováno v:
Brain, behavior, and immunity. 64
The renin-angiotensin system (RAS) is a major circulative system engaged in homeostasis modulation. Angiotensin II (Ang II) serves as its main effector hormone upon binding to its primary receptor, Ang II receptor type 1 (AT1R). It is well establishe
Autor:
Nofar Torika, Ella Roasso, Keren Asraf, Sigal Fleisher-Berkovich, Talia Filipovich-Rimon, Abraham Danon
Publikováno v:
European Journal of Pharmacology. 741:323-329
The role of kinins, well known as peripheral inflammatory mediators, in the modulation of brain inflammation is not completely understood. The present data show that bradykinin, a B2 receptor agonist, enhanced both basal and lipopolysaccharide (LPS)-
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155823 (2016)
PLoS ONE
PLoS ONE
The circulating renin-angiotensin system (RAS), including the biologically active angiotensin II, is a fundamental regulatory mechanism of blood pressure conserved through evolution. Angiotensin II components of the RAS have also been identified in t