Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Noemia S. Lima"'
Autor:
Chaim A. Schramm, Damee Moon, Lowrey Peyton, Noemia S. Lima, Christian Wake, Kristin L. Boswell, Amy R. Henry, Farida Laboune, David Ambrozak, Samuel W. Darko, I-Ting Teng, Kathryn E. Foulds, Andrea Carfi, Darin K. Edwards, Peter D. Kwong, Richard A. Koup, Robert A. Seder, Daniel C. Douek
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract As SARS-CoV-2 variants continue evolving, testing updated vaccines in non-human primates remains important for guiding human clinical practice. To date, such studies have focused on antibody titers and antigen-specific B and T cell frequenci
Externí odkaz:
https://doaj.org/article/5c17ee640e21465b8f13ef277281b87f
Autor:
Noemia S. Lima, Maryam Musayev, Timothy S. Johnston, Danielle A. Wagner, Amy R. Henry, Lingshu Wang, Eun Sung Yang, Yi Zhang, Kevina Birungi, Walker P. Black, Sijy O’Dell, Stephen D. Schmidt, Damee Moon, Cynthia G. Lorang, Bingchun Zhao, Man Chen, Kristin L. Boswell, Jesmine Roberts-Torres, Rachel L. Davis, Lowrey Peyton, Sandeep R. Narpala, Sarah O’Connell, Leonid Serebryannyy, Jennifer Wang, Alexander Schrager, Chloe Adrienna Talana, Geoffrey Shimberg, Kwanyee Leung, Wei Shi, Rawan Khashab, Asaf Biber, Tal Zilberman, Joshua Rhein, Sara Vetter, Afeefa Ahmed, Laura Novik, Alicia Widge, Ingelise Gordon, Mercy Guech, I-Ting Teng, Emily Phung, Tracy J. Ruckwardt, Amarendra Pegu, John Misasi, Nicole A. Doria-Rose, Martin Gaudinski, Richard A. Koup, Peter D. Kwong, Adrian B. McDermott, Sharon Amit, Timothy W. Schacker, Itzchak Levy, John R. Mascola, Nancy J. Sullivan, Chaim A. Schramm, Daniel C. Douek
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Vaccines against the WA1 SARS-CoV2 strain confer protection against other variants. However, the mechanisms underlying cross-protection are not fully understood. Here, the authors develop a method for rapid analysis of single B cells from patient sam
Externí odkaz:
https://doaj.org/article/b6d4d09b5933465b8ae8f4b440a22b6a
Autor:
Silvana Pereira Giozza, Ximena Pamela Díaz Bermúdez, Edna Oliveira Kara, Guilherme Amaral Calvet, Ana Maria Bispo de Filippis, Marcus Vinícius Guimarães Lacerda, Camila Helena Aguiar Bôtto-Menezes, Marcia da Costa Castilho, Rafael Freitas Oliveira Franca, Armando Menezes Neto, Casey Storme, Noemia S. Lima, Kayvon Modjarrad, Maria Cristina Pimenta de Oliveira, Gerson Fernando Mendes Pereira, Nathalie Broutet, on behalf of ZIKABRA Study Team
Publikováno v:
BMC Public Health, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background The Zika virus outbreak has triggered a set of local and global actions for a rapid, effective, and timely public health response. A World Health Organization (WHO) initiative, supported by the Department of Chronic Condition Dise
Externí odkaz:
https://doaj.org/article/205ad193ed7a43cfafe786799a60aad1
Autor:
Noemia S. Lima, Damee Moon, Samuel Darko, Rafael A. De La Barrera, Leyi Lin, Michael A. Koren, Richard G. Jarman, Kenneth H. Eckels, Stephen J. Thomas, Nelson L. Michael, Kayvon Modjarrad, Daniel C. Douek, Lydie Trautmann
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The epidemic spread of Zika virus (ZIKV), associated with devastating neurologic syndromes, has driven the development of multiple ZIKV vaccines candidates. An effective vaccine should induce ZIKV-specific T cell responses, which are shown to improve
Externí odkaz:
https://doaj.org/article/8198cc4f078b42baad26df95ded2ec3c
Autor:
Guillaume Mousseau, Rachna Aneja, Mark A. Clementz, Sonia Mediouni, Noemia S. Lima, Alexander Haregot, Cari F. Kessing, Joseph A. Jablonski, Suzie Thenin-Houssier, Nisha Nagarsheth, Lydie Trautmann, Susana T. Valente
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT Human immunodeficiency virus type 1 (HIV-1) Tat binds the viral RNA structure transactivation-responsive element (TAR) and recruits transcriptional cofactors, amplifying viral mRNA expression. The Tat inhibitor didehydro-cortistatin A (dCA)
Externí odkaz:
https://doaj.org/article/c4b6f2c1a0084651a181b6cce77eddfc
Autor:
Jeffrey S. Miller, Zachary B. Davis, Erika Helgeson, Cavan Reilly, Ann Thorkelson, Jodi Anderson, Noemia S. Lima, Siri Jorstad, Geoffrey T. Hart, John H. Lee, Jeffrey T. Safrit, Hing Wong, Sarah Cooley, Lavina Gharu, Hyunsoo Chung, Patrick Soon-Shiong, Curtis Dobrowolski, Courtney V. Fletcher, Jonathan Karn, Daniel C. Douek, Timothy W. Schacker
Publikováno v:
Nature Medicine. 28:392-400
There is no cure for HIV infection, and lifelong antiretroviral therapy (ART) is required. N-803 is an IL-15 superagonist comprised of an N72D mutant IL-15 molecule attached to its alpha receptor and a human IgG1 fragment designed to increase IL-15 a
Autor:
Noemia S, Lima, Maryam, Mukhamedova, Timothy S, Johnston, Danielle A, Wagner, Amy R, Henry, Lingshu, Wang, Eun Sung, Yang, Yi, Zhang, Kevina, Birungi, Walker P, Black, Sijy, O'Dell, Stephen D, Schmidt, Damee, Moon, Cynthia G, Lorang, Bingchun, Zhao, Man, Chen, Kristin L, Boswell, Jesmine, Roberts-Torres, Rachel L, Davis, Lowrey, Peyton, Sandeep R, Narpala, Sarah, O'Connell, Jennifer, Wang, Alexander, Schrager, Chloe Adrienna, Talana, Kwanyee, Leung, Wei, Shi, Rawan, Khashab, Asaf, Biber, Tal, Zilberman, Joshua, Rhein, Sara, Vetter, Afeefa, Ahmed, Laura, Novik, Alicia, Widge, Ingelise, Gordon, Mercy, Guech, I-Ting, Teng, Emily, Phung, Tracy J, Ruckwardt, Amarendra, Pegu, John, Misasi, Nicole A, Doria-Rose, Martin, Gaudinski, Richard A, Koup, Peter D, Kwong, Adrian B, McDermott, Sharon, Amit, Timothy W, Schacker, Itzchak, Levy, John R, Mascola, Nancy J, Sullivan, Chaim A, Schramm, Daniel C, Douek
Publikováno v:
bioRxiv : the preprint server for biology.
While humoral immune responses to infection or vaccination with ancestral SARS-CoV-2 have been well-characterized, responses elicited by infection with variants are less understood. Here we characterized the repertoire, epitope specificity, and cross
Autor:
Julie Mitchell, Victor Appay, R. Brad Jones, Alexander Haregot, Pearline Cartwright, Szu-Han Huang, Jean-Pierre Routy, Stephen Blackmore, Lydie Trautmann, Aaron Sy, Noemia S. Lima, Ayanna Garland, Nelson L. Michael, Hiroshi Takata
Publikováno v:
The Journal of Immunology. 205:699-707
The success of the shock and kill strategy for the HIV cure depends both on the reactivation of the latent reservoir and on the ability of the immune system to eliminate infected cells. As latency reversal alone has not shown any impact in the size o
Autor:
Myrna C Bonaldo, Ieda P Ribeiro, Noemia S Lima, Alexandre A C Dos Santos, Lidiane S R Menezes, Stephanie O D da Cruz, Iasmim S de Mello, Nathália D Furtado, Elaine E de Moura, Luana Damasceno, Kely A B da Silva, Marcia G de Castro, Alexandra L Gerber, Luiz G P de Almeida, Ricardo Lourenço-de-Oliveira, Ana Tereza R Vasconcelos, Patrícia Brasil
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 6, p e0004816 (2016)
BACKGROUND:Zika virus (ZIKV) is an emergent threat provoking a worldwide explosive outbreak. Since January 2015, 41 countries reported autochthonous cases. In Brazil, an increase in Guillain-Barré syndrome and microcephaly cases was linked to ZIKV i
Externí odkaz:
https://doaj.org/article/b09973507e2146abbd16ff1c914369dc
Autor:
Michael Koren, Damee Moon, Rafael De La Barrera, Noemia S. Lima, Leyi Lin, Kayvon Modjarrad, Samuel Darko, Richard G. Jarman, Stephen J. Thomas, Nelson L. Michael, Lydie Trautmann, Daniel C. Douek, Kenneth H. Eckels
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
The epidemic spread of Zika virus (ZIKV), associated with devastating neurologic syndromes, has driven the development of multiple ZIKV vaccines candidates. An effective vaccine should induce ZIKV-specific T cell responses, which are shown to improve