Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Noemi Pasquarelli"'
Autor:
Hanna Bayer, Kerstin Lang, Eva Buck, Julia Higelin, Lara Barteczko, Noemi Pasquarelli, Jasmin Sprissler, Tanja Lucas, Karlheinz Holzmann, Maria Demestre, Katrin S. Lindenberg, Karin M. Danzer, Tobias Boeckers, Albert C. Ludolph, Luc Dupuis, Patrick Weydt, Anke Witting
Publikováno v:
Neurobiology of Disease, Vol 97, Iss , Pp 36-45 (2017)
Background: Monogenetic forms of amyotrophic lateral sclerosis (ALS) offer an opportunity for unraveling the molecular mechanisms underlying this devastating neurodegenerative disorder. In order to identify a link between ALS-related metabolic change
Externí odkaz:
https://doaj.org/article/4688a059a6104c1f91a58f9015d36f2d
Autor:
Eva Buck, Hanna Bayer, Katrin S. Lindenberg, Johannes Hanselmann, Noemi Pasquarelli, Albert C. Ludolph, Patrick Weydt, Anke Witting
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Neurodegenerative diseases are characterized by distinct patterns of neuronal loss. In amyotrophic lateral sclerosis (ALS) upper and lower motoneurons degenerate whereas in Huntington’s disease (HD) medium spiny neurons in the striatum are preferen
Externí odkaz:
https://doaj.org/article/063d7b7a982341c0b7c2c713923adc12
Autor:
Jan-Michael Prill, Vladimír Subr, Noemi Pasquarelli, Tatjana Engler, Andrea Hoffmeister, Stefan Kochanek, Karel Ulbrich, Florian Kreppel
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e82716 (2014)
Capsid surface shielding of adenovirus vectors with synthetic polymers is an emerging technology to reduce unwanted interactions of the vector particles with cellular and non-cellular host components. While it has been shown that attachment of shield
Externí odkaz:
https://doaj.org/article/42591f8d4d6a46c1900a5d7a74ce25ff
Autor:
Francesco Borriello, Noemi Pasquarelli, Lisa Law, Kim Rand, Catarina Raposo, Wei Wei, Licinio Craveiro, Tobias Derfuss
Publikováno v:
Journal of Allergy and Clinical Immunology. 150:1216-1224
During the first year of life, B-cell level is a valuable indicator of whether external factors, such as exposure to B-cell-depleting therapies, have an adverse impact on immune system development. However, there are no standard reference ranges of B
Autor:
Riley Bove, Kerstin Hellwig, Noemi Pasquarelli, Francesco Borriello, Ruth Dobson, Celia Oreja-Guevara, Chien-Ju Lin, Dusanka Zecevic, Licinio Craveiro, Thomas McElrath, Sandra Vukusic
Publikováno v:
Multiple sclerosis and related disorders. 64
Most disease-modifying therapies (DMTs) approved for the treatment of multiple sclerosis (MS) are not recommended during pregnancy, and discouraged while breastfeeding. However, discontinuation of some DMTs before pregnancy can leave women vulnerable
Autor:
Victor Gitman, Aphrodite Stavropoulos, Victoria Saenz, Noemi Pasquarelli, Dusanka Zecevic, Virginia Devonshire
Publikováno v:
Multiple sclerosis and related disorders. 62
To report and describe the real-world use of ocrelizumab in women with multiple sclerosis (MS) in Canada before and/or during pregnancy as well as their fetal outcomes.We identified retrospective and prospective Canadian pregnancy exposure cases from
Autor:
Sandra Vukusic, Ruth Dobson, Riley M. Bove, Kerstin Hellwig, Noemi Pasquarelli, Dusanka Zecevic, Celia Oreja-Guevara
Publikováno v:
Revue Neurologique. 178:S112
Publikováno v:
Behavioural Brain Research. 333:35-42
The development of modern housing regimes such as individually ventilated cage (IVC) systems has become very popular and attractive in order to reduce spreading of pathogenic organisms and to lower the risk to develop a laboratory animal allergy for
Autor:
Dusanka Zecevic, Kerstin Hellwig, Regine Buffels, Riley Bove, Sandra Vukusic, Noemi Pasquarelli, Celia Oreja-Guevara
Publikováno v:
Revue Neurologique. 177:S106
Introduction Orelizumab (OCR) est un anticorps monoclonal humanise anti-CD20 utilise dans le traitement de la SEP recurrente et primaire progressive. La SEP affectant des femmes en âge de procreer, des grossesses sous OCR peuvent survenir. Objectifs
Autor:
Anke Witting, Johannes Hanselmann, Patrick Weydt, Boris Ferger, Christoph Porazik, Noemi Pasquarelli
Publikováno v:
Neuropharmacology. 91:148-156
Monoacylglycerol lipase (MAGL) is part of the endocannabinoid and the prostaglandin signaling system. MAGL degrades the endocannabinoid 2-arachidonoylglycerol (2-AG) into glycerol and arachidonic acid. MAGL-induced arachidonic acid is the primary sou