Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Noemi Andor"'
Autor:
Chandler D. Gatenbee, Ann-Marie Baker, Sandhya Prabhakaran, Ottilie Swinyard, Robbert J. C. Slebos, Gunjan Mandal, Eoghan Mulholland, Noemi Andor, Andriy Marusyk, Simon Leedham, Jose R. Conejo-Garcia, Christine H. Chung, Mark Robertson-Tessi, Trevor A. Graham, Alexander R. A. Anderson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Interest in spatial omics is on the rise, but generation of highly multiplexed images remains challenging, due to cost, expertise, methodical constraints, and access to technology. An alternative approach is to register collections of whole
Externí odkaz:
https://doaj.org/article/27aa67cd79b24cdf8baff050f7387c85
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-11 (2022)
Abstract Deep-learning classification systems have the potential to improve cancer diagnosis. However, development of these computational approaches so far depends on prior pathological annotations and large training datasets. The manual annotation i
Externí odkaz:
https://doaj.org/article/a21435a0720d4fe6b08b5a429358461d
Autor:
Gregory J Kimmel, Richard J Beck, Xiaoqing Yu, Thomas Veith, Samuel Bakhoum, Philipp M Altrock, Noemi Andor
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 1, p e1010815 (2023)
The phenotypic efficacy of somatic copy number alterations (SCNAs) stems from their incidence per base pair of the genome, which is orders of magnitudes greater than that of point mutations. One mitotic event stands out in its potential to significan
Externí odkaz:
https://doaj.org/article/5f9f342ad0e049328222bb91f9f49173
Publikováno v:
Cells, Vol 12, Iss 14, p 1849 (2023)
Many cancer cell lines are aneuploid and heterogeneous, with multiple karyotypes co-existing within the same cell line. Karyotype heterogeneity has been shown to manifest phenotypically, thus affecting how cells respond to drugs or to minor differenc
Externí odkaz:
https://doaj.org/article/1dca932a4fdb4274b6797d3c63177b2a
Publikováno v:
Frontiers in Artificial Intelligence, Vol 4 (2021)
The emergence of the information age in the last few decades brought with it an explosion of biomedical data. But with great power comes great responsibility: there is now a pressing need for new data analysis algorithms to be developed to make sense
Externí odkaz:
https://doaj.org/article/8ff16926d04b47d58eafc45cbe55a484
Autor:
Mathieu Daynac, Malek Chouchane, Hannah Y. Collins, Nicole E. Murphy, Noemi Andor, Jianqin Niu, Stephen P. J. Fancy, William B. Stallcup, Claudia K. Petritsch
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Oligodendrocyte progenitor cells (OPCs) undergo asymmetric cell division, and disruption of such mechanism can generate oligodendroglioma precursors. Here, Daynac and colleagues show that Lgl1 regulates asymmetric division and differentiation of OPCs
Externí odkaz:
https://doaj.org/article/26828c1df785418aa023dd61fa643620
Observed (experimentally measured) 1D growth patterns
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ccee102a579cb3a36bb219e1a53630d
https://doi.org/10.1158/0008-5472.22425924.v1
https://doi.org/10.1158/0008-5472.22425924.v1
Simulation parameters
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b1c6b110d2f459de78692f0c8db60e8
https://doi.org/10.1158/0008-5472.22425927.v1
https://doi.org/10.1158/0008-5472.22425927.v1
Simulation shown in Fig. 4F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cba0f4f4fbaddaab55a4215fdb7aedbf
https://doi.org/10.1158/0008-5472.22425915
https://doi.org/10.1158/0008-5472.22425915
Supplementary Methods, Figures 1-6 and Tables 1-3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3281cbff76091a3552be9fb668379514
https://doi.org/10.1158/0008-5472.22425912
https://doi.org/10.1158/0008-5472.22425912