Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Noemi A. Guadagno"'
Autor:
Noemi A. Guadagno, Claudia Moriconi, Valerio Licursi, Emanuela D'Acunto, Paola S. Nisi, Nicoletta Carucci, Antonella De Jaco, Emanuele Cacci, Rodolfo Negri, Giuseppe Lupo, Elena Miranda
Publikováno v:
Neurobiology of Disease, Vol 103, Iss , Pp 32-44 (2017)
The serpinopathies are human pathologies caused by mutations that promote polymerisation and intracellular deposition of proteins of the serpin superfamily, leading to a poorly understood cell toxicity. The dementia FENIB is caused by polymerisation
Externí odkaz:
https://doaj.org/article/40f41ac322b146d2a0e0a47bb55bb048
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104250- (2022)
Summary: Rab proteins are well known regulators of intracellular trafficking; however, more and more studies point to their function also in other cellular processes, including cell migration. In this work, we have performed an siRNA screen to identi
Externí odkaz:
https://doaj.org/article/ae40fa7d820a492b86a14a771e3079fa
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Tumor progression is a complex process consisting of several steps characterized by alterations in cellular behavior and morphology. These steps include uncontrolled cell division and proliferation, invasiveness and metastatic ability. Throughout the
Externí odkaz:
https://doaj.org/article/9930d41e9a1a4ae6a4dcfa44b76d629b
Autor:
Irene Persiconi, Francesca Cosmi, Noemi Antonella Guadagno, Giuseppe Lupo, Maria Egle De Stefano
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Duchenne muscular dystrophy (DMD) is a lethal X-linked muscular disease caused by defective expression of the cytoskeletal protein dystrophin (Dp427). Selected autonomic and central neurons, including retinal neurons, express Dp427 and/or dystrophin
Externí odkaz:
https://doaj.org/article/ce37be39ef1b4f9589ffe0d62c3de4ce
Autor:
Noemi A. Guadagno, Cinzia Progida
Publikováno v:
Cell Migration in Three Dimensions ISBN: 9781071628867
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea3b1cdb0318794041525e8bf50eb4da
https://doi.org/10.1007/978-1-0716-2887-4_3
https://doi.org/10.1007/978-1-0716-2887-4_3
Publikováno v:
Cells, Vol 8, Iss 8, p 909 (2019)
Rab proteins compose the largest family of small GTPases and control the different steps of intracellular membrane traffic. More recently, they have been shown to also regulate cell signaling, division, survival, and migration. The regulation of thes
Externí odkaz:
https://doaj.org/article/f67d40dad5e842b498779cf1f56022da
Autor:
Catharina Arnold-Schrauf, Nadia Mensali, Katharina Vestre, Cinzia Progida, Ana-Maria Lennon-Duménil, Oddmund Bakke, Noemi Antonella Guadagno, Irene Persiconi, Marine Bretou, Marc Dalod, Marita Borg Distefano, Sébastien Wälchli
Publikováno v:
Journal of Cell Science
Journal of Cell Science, 2021, 134 (18), pp.jcs259221. ⟨10.1242/jcs.259221⟩
article-version (VoR) Version of Record
Journal of Cell Science, Company of Biologists, 2021, 134 (18), pp.jcs259221. ⟨10.1242/jcs.259221⟩
Journal of Cell Science, 2021, 134 (18), pp.jcs259221. ⟨10.1242/jcs.259221⟩
article-version (VoR) Version of Record
Journal of Cell Science, Company of Biologists, 2021, 134 (18), pp.jcs259221. ⟨10.1242/jcs.259221⟩
Lysosomal signaling facilitates the migration of immune cells by releasing Ca2+ to activate the actin-based motor myosin II at the cell rear. However, how the actomyosin cytoskeleton physically associates to lysosomes is unknown. We have previously i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3135a670125015791138a20ec1570df7
https://doi.org/10.1242/jcs.259221
https://doi.org/10.1242/jcs.259221
Autor:
Felix Kohler, Ingrid Kjos, Oddmund Bakke, Federico Fenaroli, Noemi Antonella Guadagno, Marita Borg Distefano, Katharina Vestre, Cinzia Progida
Publikováno v:
Cellular and Molecular Life Sciences. 76:2593-2614
Rab proteins are master regulators of intracellular membrane trafficking, but they also contribute to cell division, signaling, polarization, and migration. The majority of the works describing the mechanisms used by Rab proteins to regulate cell mot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5893aae1c243109e83002057681a2ba1
https://doi.org/10.1007/s00018-019-03057-w
https://doi.org/10.1007/s00018-019-03057-w
Publikováno v:
Nanoscale Research Letters
Nanoscale Research Letters, Vol 16, Iss 1, Pp 1-14 (2021)
Nanoscale Research Letters, Vol 16, Iss 1, Pp 1-14 (2021)
Background In this work, we explore how U2OS cells are affected by arrays of polymer nanopillars fabricated on flat glass surfaces. We focus on describing changes to the organisation of the actin cytoskeleton and in the location, number and shape of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e4c5461768c44e35bd79cc450dccc94
https://doi.org/10.1101/2020.09.14.289330
https://doi.org/10.1101/2020.09.14.289330
Autor:
Cinzia Progida, Synne Arstad Bjørnestad, Felix Margadant, Azzurra Margiotta, Xian Hu, Oddmund Bakke, Noemi Antonella Guadagno, Xiaochun Xu, Linda Hofstad Haugen, Ingrid Kjos
Publikováno v:
The Journal of Cell Biology
Guadagno et al. reveal that the small GTPase Rab18, by interacting directly with the ER-resident protein kinectin, regulates the ER transport toward the cell surface to support focal adhesion growth and sustain protrusion orientation during chemotaxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbd72a14c71e35ea62695819fe3f8a01
http://europepmc.org/articles/PMC7337506
http://europepmc.org/articles/PMC7337506