Mapping molecular binding by means of conformational dynamics measurements

Autor: Augusto Juste-Dolz, Paulo Roberto Bueno, Isidro S. Monzó, Sergi Morais, Ángel Maquieira, David Giménez-Romero, José Luis López-Paz, Roberto Tejero, Noelle M. do Nascimento

Publikováno v: RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

[EN] Protein-protein interactions are key in virtually all biological processes. The study of these interactions and the interfaces that mediate them play a key role in the understanding of biological function. In particular, the observation of prote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e8b62a6a2d6b9b9165b925ace0c37c
https://doi.org/10.1039/c7ra10617c

New structural insights into the role of TROVE2 complexes in the on-set and pathogenesis of systemic lupus erythematosus determined by a combination of QCM-D and DPI

Autor: Isidro S. Monzó, José Andrés Román-Ivorra, David Giménez-Romero, Noelle M. do Nascimento, José Luis López-Paz, Elena Grau-García, Jorge Escorihuela, Ángel Maquieira, Augusto Juste-Dolz, Rosa Puchades, Sergi Morais

Publikováno v: RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname

[EN] The mechanism of self-recognition of the autoantigen TROVE2, a common biomarker in autoimmune diseases, has been studied with a quartz crystal microbalance with dissipation monitoring (QCM-D) and dual polarization interferometry (DPI). The compl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1624a739927ec48e6ed4fb115f7b3cb
https://pubmed.ncbi.nlm.nih.gov/30317445