Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Noelle B Patterson"'
Autor:
Emily C Smith, Keith J Limbach, Nonenipha Rangel, Kyosuke Oda, Jessica S Bolton, Mengyan Du, Kalpana Gowda, Jianyang Wang, J Kathleen Moch, Sharvari Sonawane, Rachel Velasco, Arnel Belmonte, Rebecca Danner, Joanne M Lumsden, Noelle B Patterson, Martha Sedegah, Michael R Hollingdale, Thomas L Richie, John B Sacci, Eileen D Villasante, Joao C Aguiar
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0232234 (2020)
Only a small fraction of the antigens expressed by malaria parasites have been evaluated as vaccine candidates. A successful malaria subunit vaccine will likely require multiple antigenic targets to achieve broad protection with high protective effic
Externí odkaz:
https://doaj.org/article/40acdf05876945a1bcc1de9efe418dee
Autor:
Joao C Aguiar, Jessica Bolton, Joyce Wanga, John B Sacci, Hideyuki Iriko, Julie K Mazeika, Eun-Taek Han, Keith Limbach, Noelle B Patterson, Martha Sedegah, Ann-Marie Cruz, Takafumi Tsuboi, Stephen L Hoffman, Daniel Carucci, Michael R Hollingdale, Eileen D Villasante, Thomas L Richie
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136109 (2015)
Nearly 100% protection against malaria infection can be achieved in humans by immunization with P. falciparum radiation-attenuated sporozoites (RAS). Although it is thought that protection is mediated by T cell and antibody responses, only a few of t
Externí odkaz:
https://doaj.org/article/fc6f144e9a7d4c3f82e1b6bcf1243227
Autor:
Joseph T Bruder, Elena Semenova, Ping Chen, Keith Limbach, Noelle B Patterson, Maureen E Stefaniak, Svetlana Konovalova, Charlie Thomas, Melissa Hamilton, C Richter King, Thomas L Richie, Denise L Doolan
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e33920 (2012)
The development of an effective malaria vaccine is a high global health priority. Vaccine vectors based on adenovirus type 5 are capable of generating robust and protective T cell and antibody responses in animal models and are currently being evalua
Externí odkaz:
https://doaj.org/article/a5d21dfeacc34529810ff1df47ca014f
Autor:
Martha Sedegah, Cindy Tamminga, Shannon McGrath, Brent House, Harini Ganeshan, Jennylynn Lejano, Esteban Abot, Glenna J Banania, Renato Sayo, Fouzia Farooq, Maria Belmonte, Nalini Manohar, Nancy O Richie, Chloe Wood, Carole A Long, David Regis, Francis T Williams, Meng Shi, Ilin Chuang, Michele Spring, Judith E Epstein, Jose Mendoza-Silveiras, Keith Limbach, Noelle B Patterson, Joseph T Bruder, Denise L Doolan, C Richter King, Lorraine Soisson, Carter Diggs, Daniel Carucci, Sheetij Dutta, Michael R Hollingdale, Christian F Ockenhouse, Thomas L Richie
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e24586 (2011)
Models of immunity to malaria indicate the importance of CD8+ T cell responses for targeting intrahepatic stages and antibodies for targeting sporozoite and blood stages. We designed a multistage adenovirus 5 (Ad5)-vectored Plasmodium falciparum mala
Externí odkaz:
https://doaj.org/article/9c9a093b9e1d42e4bfd2af438749573f
Autor:
Cindy Tamminga, Martha Sedegah, David Regis, Ilin Chuang, Judith E Epstein, Michele Spring, Jose Mendoza-Silveiras, Shannon McGrath, Santina Maiolatesi, Sharina Reyes, Victoria Steinbeiss, Charlotte Fedders, Kathryn Smith, Brent House, Harini Ganeshan, Jennylynn Lejano, Esteban Abot, Glenna J Banania, Renato Sayo, Fouzia Farooq, Maria Belmonte, Jittawadee Murphy, Jack Komisar, Jackie Williams, Meng Shi, Donald Brambilla, Nalini Manohar, Nancy O Richie, Chloe Wood, Keith Limbach, Noelle B Patterson, Joseph T Bruder, Denise L Doolan, C Richter King, Carter Diggs, Lorraine Soisson, Daniel Carucci, Gail Levine, Sheetij Dutta, Michael R Hollingdale, Christian F Ockenhouse, Thomas L Richie
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25868 (2011)
A protective malaria vaccine will likely need to elicit both cell-mediated and antibody responses. As adenovirus vaccine vectors induce both these responses in humans, a Phase 1/2a clinical trial was conducted to evaluate the efficacy of an adenoviru
Externí odkaz:
https://doaj.org/article/97a1ce60fb5e4006ae377a92a4081a31
Autor:
Laura Padula, Eva Fisher, Wathsala Wijayalath, Noelle B. Patterson, Jun Huang, Harini Ganeshan, Tanisha Robinson, François A. Bates, Margaret A. Hanson, Monica L. Martin, Katelyn Rivas, Denisse Garcia, Kimberly A. Edgel, Martha Sedegah, Eileen Villasante, Natasa Strbo
Publikováno v:
Frontiers in Immunology. 14
IntroductionA highly efficacious and durable vaccine against malaria is an essential tool for global malaria eradication. One of the promising strategies to develop such a vaccine is to induce robust CD8+ T cell mediated immunity against malaria live
Autor:
Arnel Belmonte, Ivelese Guzman, D Bellamy, Cindy Tamminga, Michael R. Hollingdale, Eleanor Berrie, Jo Glenna Banania, Elke S. Bergmann-Leitner, Martha Sedegah, Judith E. Epstein, Maria Belmonte, Sharina Reyes, Eileen Villasante, Anatalio Reyes, Yolanda Alcorta, Tida Lee, Rachel Velasco, Devin Hunt, Katie J. Ewer, Thomas L. Richie, Keith Limbach, Kalpana Gowda, Alison M. Lawrie, Jack Hutter, Marvin J Sklar, Nehkonti Adams, Noelle B. Patterson, Lindsey S. Garver, Ashley Lindstrom, Nimfa Teneza-Mora, M Bittaye, Lorraine Soisson, Carter L. Diggs, Mimi Wong, Harini Ganeshan, Ilin Chuang, Sandra Inoue, Adrian V. S. Hill, Christopher A. Duplessis, Jun Huang, K. Monique Hollis-Perry, Santina Maiolatesi, Kelli Bankard, Sidhartha Chaudhury
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0256980 (2021)
PLoS ONE
PLoS ONE
BackgroundA DNA-prime/human adenovirus serotype 5 (HuAd5) boost vaccine encodingPlasmodium falciparum(Pf) circumsporozoite protein (PfCSP) and Pf apical membrane antigen-1 (PfAMA1), elicited protection in 4/15 (27%) of subjects against controlled hum
Autor:
Nonenipha Rangel, Emily C. Smith, Joanne M. Lumsden, Mengyan Du, Noelle B. Patterson, Jianyang Wang, Sharvari Sonawane, Kalpana Gowda, Rebecca Danner, Kyosuke Oda, Michael R. Hollingdale, J. Kathleen Moch, Eileen D. Villasante, Thomas L. Richie, Rachel Velasco, Joao C. Aguiar, Martha Sedegah, Jessica Bolton, Keith Limbach, Arnel Belmonte, John B. Sacci
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0232234 (2020)
PLoS ONE
PLoS ONE
Only a small fraction of the antigens expressed by malaria parasites have been evaluated as vaccine candidates. A successful malaria subunit vaccine will likely require multiple antigenic targets to achieve broad protection with high protective effic
Autor:
Gary R. Matyas, Fanta Kalle, Carl R. Alving, Timothy W. Phares, Maureen E. Stefaniak, Keith Limbach, Christopher J. Genito, Elke S. Bergmann-Leitner, Noelle B. Patterson, Zoltan Beck, Sheetij Dutta, Norman C. Waters
Publikováno v:
Vaccine. 35:3865-3874
Malaria caused by Plasmodium falciparum continues to threaten millions of people living in the tropical parts of the world. A vaccine that confers sterile and life-long protection remains elusive despite more than 30years of effort and resources inve
Autor:
Natasa Strbo, Laura Padula, Eva Fisher, Wathsala Wijayalath, Noelle B. Patterson, Jun Huang, Harini Ganeshan, Katelyn O’Neill, Denisse Garcia, Irina V. Etobayeva, Kimberly A. Edgel, Eckhard R Podack, Martha Sedegah, Eileen F. Villasante
Publikováno v:
The Journal of Immunology. 204:168.2-168.2
A highly-efficacious and durable malaria vaccine is an essential tool for global malaria eradication. One promising strategy to develop such a vaccine is to induce robust CD8+ T cell-mediated protective immunity against malaria liver stage parasites.