Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Noell, Cho"'
Autor:
Noell Cho, Georgina Kontou, Joshua L. Smalley, Christopher Bope, Jacob Dengler, Kristopher Montrose, Tarek Z. Deeb, Nicholas J. Brandon, Tadashi Yamamoto, Paul A. Davies, Georgios Giamas, Stephen J. Moss
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109512- (2024)
Summary: LMTK3 is a brain-specific transmembrane serine/threonine protein kinase that acts as a scaffold for protein phosphatase-1 (PP1). Although LMKT3 has been identified as a risk factor for autism and epilepsy, its physiological significance is u
Externí odkaz:
https://doaj.org/article/fe648812ed2245d28cd51d531ae0f3c3
Autor:
Joshua L. Smalley, Noell Cho, Shu Fun Josephine Ng, Catherine Choi, Abigail H. S. Lemons, Saad Chaudry, Christopher E. Bope, Jake S. Dengler, Chuansheng Zhang, Matthew N. Rasband, Paul A. Davies, Stephen J. Moss
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
The subunit composition of GABAA receptors and their interaction with beta spectrin complexes influences their localization between the neuronal axon initial segment or dendrites.
Externí odkaz:
https://doaj.org/article/edfc1bb22db642f7ab73e66911075353
Autor:
Joshua L, Smalley, Noell, Cho, Shu Fun Josephine, Ng, Catherine, Choi, Abigail H S, Lemons, Saad, Chaudry, Christopher E, Bope, Jake S, Dengler, Chuansheng, Zhang, Matthew N, Rasband, Paul A, Davies, Stephen J, Moss
Publikováno v:
Communications biology. 6(1)
Fast synaptic inhibition is dependent on targeting specific GABA
Autor:
Jacqueline G. O’Rourke, Galinos Barmparas, Audrey R. Yang, Navpreet K. Dhillon, Noell Cho, Nikhil T Linaval, Oksana Shelest, Eric J. Ley
Publikováno v:
The journal of trauma and acute care surgery. 89(5)
Background How recurrent traumatic brain injury (rTBI) alters brain function years after insult is largely unknown. This study aims to characterize the mechanistic cause for long-term brain deterioration following rTBI using a rat model. Methods Eigh
Autor:
Joshua J. Breunig, Virginia B. Mattis, Gi-Bum Kim, Leslie Garcia, Steve E. Savinoff, David Saxon, George Lawless, Brandon Shelley, Hannah Park, Naomi Kobritz, Colton M Tom, Noell Cho, Aslam Abbasi Akhtar, Genevieve Gowing, Clive N. Svendsen
Publikováno v:
Stem Cell Reports
Summary Trophic factor delivery to the brain using stem cell-derived neural progenitors is a powerful way to bypass the blood-brain barrier. Protection of diseased neurons using this technology is a promising therapy for neurodegenerative diseases. G
Autor:
Gretchen M. Thomsen, Jean-Philippe Vit, Patrick Suezaki, Livia Wyss, Oksana Shelest, Krystof S. Bankiewicz, Pablo Avalos, Clive N. Svendsen, Noell Cho, Mor Alkaslasi, Annie A. Ma, Marlesa Godoy
Publikováno v:
Stem Cells. 36:1122-1131
Early dysfunction of cortical motor neurons may underlie the initiation of amyotrophic lateral sclerosis (ALS). As such, the cortex represents a critical area of ALS research and a promising therapeutic target. In the current study, human cortical-de
Autor:
Ara Ko, Patricia S. Haro, Jean-Philippe Vit, Gretchen M. Thomsen, Navpreet K. Dhillon, Livia Wyss, Eric J. Ley, Noell Cho, Annie Ma, Megan Y. Harada, Pablo Avalos, Oksana Shelest
Publikováno v:
The journal of trauma and acute care surgery. 82(6)
Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease linked to repetitive head injuries. Chronic traumatic encephalopathy symptoms include changes in mood, behavior, cognition, and motor function; however, CTE is currently diagnosed