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Akademický článek

Detection of Phospho-KRAS by Electrophoretic Mobility Change in Human Cell Lines and in Tumor Samples from Nude Mice Grafts

Autor: Carles Barceló, Noelia Paco, Debora Cabot, Eduard Garrido, Neus Agell, Montserrat Jaumot

Publikováno v: Bio-Protocol, Vol 5, Iss 6 (2015)

KRAS is the oncogene most frequently mutated in human solid tumors especially in pancreas, colon, small intestine, biliary tract and lung. We have recently demonstrated that oncogenic KRAS needs S181 phosphorylation to fully display its oncogenic fea

Externí odkaz: https://doaj.org/article/d61cfd6e960840b09e43d3b90650388a

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Management, Survival, and Costs of Pancreatic Cancer: Population-Based Observational Study in Catalonia

Autor: Laura Guarga, Noelia Paco, Paula Manchon-Walsh, Emili Vela, Joaquim Delgadillo, Caridad Pontes, Josep Maria Borràs

Publikováno v: International Journal of Environmental Research and Public Health; Volume 20; Issue 9; Pages: 5673

Aim: Few published studies comprehensively describe the characteristics of patients with pancreatic cancer and their treatment in clinical practice. This study aimed to describe the current clinical practice for treating pancreatic cancer in Cataloni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ba2eff1e9fef901e93e2ea208d53fae

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Data from Phosphorylation at Ser-181 of Oncogenic KRAS Is Required for Tumor Growth

Autor: Neus Agell, Gabriel Capella, Felip Vilardell, Montserrat Jaumot, Neus Bota-Rabassedas, Blanca Alvarez-Moya, Mireia Morell, Noelia Paco, Carles Barceló

KRAS phosphorylation has been reported recently to modulate the activity of mutant KRAS protein in vitro. In this study, we defined S181 as a specific phosphorylation site required to license the oncogenic function of mutant KRAS in vivo. The phospho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5966582c44df14417050c2f9b468cb0e
https://doi.org/10.1158/0008-5472.c.6505818

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Supplementary Tables 1 - 3 from Phosphorylation at Ser-181 of Oncogenic KRAS Is Required for Tumor Growth

Autor: Neus Agell, Gabriel Capella, Felip Vilardell, Montserrat Jaumot, Neus Bota-Rabassedas, Blanca Alvarez-Moya, Mireia Morell, Noelia Paco, Carles Barceló

PDF file - 20K, Table S1. Statistics for the values of volumes (mm3) represented in Fig1 pannel B. Table S2. Statistics for the values of weights (g) represented in Fig1 panel C. Table S3. KRAS mutations I tumor cell lines used to determine PKC inhib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ddf4902d3caef434720616f89e9bd79
https://doi.org/10.1158/0008-5472.22401309

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