Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Noelia P. Di Giorgio"'
Autor:
Noelia P. Di Giorgio, Marianne Bizzozzero-Hiriart, Pablo N. Surkin, Esteban Repetto, María M. Bonaventura, Florencia N. Tabares, Nadia S. Bourguignon, Ayelén Converti, Juan M. Riaño Gomez, Bernhard Bettler, Victoria Lux-Lantos
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 324:E314-E329
We developed a unique mouse lacking GABAB receptors specifically in Kiss1 cells to evaluate the impact on reproduction and metabolism. Knockout males showed a severe impact on glucose homeostasis, which worsened with aging. These results reinforce th
Publikováno v:
Neuroendocrinology. 112:998-1026
Introduction: The kisspeptin gene Kiss1 is expressed in two hypothalamic areas: anteroventral periventricular nucleus/periventricular nucleus (AVPV/PeN) and arcuate nucleus (ARC), and also in gonads. Several pieces of evidence suggests that gamma-ami
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 318(6)
Lack of GABA
Autor:
Noelia P, Di Giorgio, Paolo N, Catalano, Paula V, López, Betina, González, Sheila J, Semaan, Gabriela C, López, Alexander S, Kauffman, Susana B, Rulli, Gustavo M, Somoza, Bernhard, Bettler, Carlos, Libertun, Victoria A, Lux-Lantos
Publikováno v:
Neuroendocrinology
BACKGROUND/AIMS Adult mice lacking functional GABAB receptors (GABAB1KO) show altered Gnrh1 and Gad1 expressions in the preoptic area anterior hypothalamus (POA AH) and females display disruption of cyclicity and fertility. Here we addressed whether