Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Noelia J. Kunzevitzky"'
Autor:
Alexander Kreymerman, David N. Buickians, Michael M. Nahmou, Tammy Tran, Joana Galvao, Yan Wang, Nicholas Sun, Leah Bazik, Star K. Huynh, In-Jae Cho, Tomasz Boczek, Kun-Che Chang, Noelia J. Kunzevitzky, Jeffrey L. Goldberg
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Abstract The process of mitochondrial fission-fusion has been implicated in diverse neuronal roles including neuronal survival, axon degeneration, and axon regeneration. However, whether increased fission or fusion is beneficial for neuronal health a
Externí odkaz:
https://doaj.org/article/0215dae8fa5149f99d708b4117f0df14
Autor:
Jeffrey L. Goldberg, Dillon J. Rak, Melissa Atkins, Xin Xia, Noelia J. Kunzevitzky, Roopa Dalal, Catalina B. Sun, C. Andres Benatti, Olga Kuzmenko, Michael Nahmou, Kun-Che Chang
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Corneal endothelial dysfunction leads to corneal edema, pain, and vision loss. Adequate animal models are needed to study the safety and efficacy of novel cell therapies as an alternative to corneal transplantation. Methods Primary human corn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38359094299c4a9068a2e509547955cc
http://europepmc.org/articles/PMC6546151
http://europepmc.org/articles/PMC6546151
Autor:
Tejas Nimish Shah, Jeffrey L. Goldberg, Darcie L. Moore, Masoumeh Ashouri, Noelia J. Kunzevitzky, Joana Galvao, Murray Blackmore, Yan Wang, Akintomide Apara, Keiichiro Iwao
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Adult central nervous system (CNS) neurons are unable to regenerate their axons after injury. Kruppel-like transcription factor (KLF) family members regulate intrinsic axon growth ability in vitro and in vivo, but mechanisms downstream of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f582bb6f5ae3c095ec967f7bd5a98ade
http://europepmc.org/articles/PMC5983061
http://europepmc.org/articles/PMC5983061
Autor:
Xiong Zhang, Joana Galvao, Allison Trillo, Akintomide Apara, Kimberly A. Fernandes, Jeffrey L. Goldberg, Keiichiro Iwao, Murray Blackmore, Peter X. Shaw, Richard T. Libby, Darcie L. Moore, Yan Wang, Masoumeh Ashouri, Abigail Huang, Tu Nguyen, Noelia J. Kunzevitzky, Dale P. Brown
Publikováno v:
The Journal of Neuroscience. 37:9632-9644
Neurons in the adult mammalian CNS decrease in intrinsic axon growth capacity during development in concert with changes in Krüppel-like transcription factors (KLFs). KLFs regulate axon growth in CNS neurons including retinal ganglion cells (RGCs).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12ae71fbed83b1c063ab41e68e41b82a
https://doi.org/10.1523/jneurosci.0643-16.2017
https://doi.org/10.1523/jneurosci.0643-16.2017
Autor:
Michael Nahmou, Star K. Huynh, Nicholas Sun, Yan Wang, Tomasz Boczek, David Buickians, Tammy Tran, Kun-Che Chang, In-Jae Cho, Joana Galvao, Alexander Kreymerman, Leah Bazik, Jeffrey L. Goldberg, Noelia J. Kunzevitzky
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
The process of mitochondrial fission-fusion has been implicated in diverse neuronal roles including neuronal survival, axon degeneration, and axon regeneration. However, whether increased fission or fusion is beneficial for neuronal health and/or axo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce322280e3b622bb0c59cb417241e566
http://europepmc.org/articles/PMC6650498
http://europepmc.org/articles/PMC6650498
Autor:
Jeffrey L. Goldberg, Alena Bartakova, Karen Alvarez-Delfin, Richard M. Merkhofer, Gabriella A. Raffa, Alejandra D. Weisman, Enrique Salero, Noelia J. Kunzevitzky
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Human corneal endothelial cell (HCEC) density decreases with age, surgical complications, or disease, leading to vision impairment. Such endothelial dysfunction is an indication for corneal transplantation, although there is a worldwide short
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c2c874cb5fb95e2cb0d9aaaa9c40182
http://europepmc.org/articles/PMC4884060
http://europepmc.org/articles/PMC4884060
Autor:
Alena Bartakova, Jeffrey L. Goldberg, Noelia J. Kunzevitzky, Karen Alvarez-Delfin, Olga Kuzmenko
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Cell-based therapies to replace corneal endothelium depend on culture methods to optimize human corneal endothelial cell (HCEC) function and minimize endothelial-mesenchymal transition (EnMT). Here we explore contribution of low-mitogenic med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe643d37ace319ae66ffb855edc0701a
https://doi.org/10.1167/iovs.17-23637
https://doi.org/10.1167/iovs.17-23637
Autor:
Meghan Cameron, Jeffrey L. Goldberg, Ben A. Barres, Noelia J. Kunzevitzky, Jack T. Wang, Jason C. Dugas
Publikováno v:
The Journal of Neuroscience. 27:8593-8603
To what extent do postmitotic neurons regulate gene expression during development or after injury? We took advantage of our ability to highly purify retinal ganglion cells (RGCs) to profile their pattern of gene expression at 13 ages from embryonic d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f52ea3d6db8537777ae1195922d848b9
https://doi.org/10.1523/jneurosci.4488-06.2007
https://doi.org/10.1523/jneurosci.4488-06.2007
Autor:
Xin Xia, Jeffrey L. Goldberg, Kathryn L. McCabe, Noelia J. Kunzevitzky, Brian Chiswell, Robert Lanza
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 12, p e0145266 (2015)
PLoS ONE, Vol 10, Iss 12, p e0145266 (2015)
Aim To generate human embryonic stem cell derived corneal endothelial cells (hESC-CECs) for transplantation in patients with corneal endothelial dystrophies. Materials and Methods Feeder-free hESC-CECs were generated by a directed differentiation pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c1d40b9a764f6ab051cfbba83f8b78b
https://pubmed.ncbi.nlm.nih.gov/26689688
https://pubmed.ncbi.nlm.nih.gov/26689688
Endothelial cell dysfunction as in Fuchs dystrophy or pseudophakic bullous keratopathy, and the limited regenerative capacity of human corneal endothelial cells (HCECs), drive the need for corneal transplant. In response to limited donor corneal avai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76989775991a1cd484d635eef2272842
https://europepmc.org/articles/PMC4196268/
https://europepmc.org/articles/PMC4196268/
