Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Noelia Fonseca"'
Autor:
Sara Garcia-Garcia, Maria Rodrigo-Faus, Noelia Fonseca, Sara Manzano, Balázs Győrffy, Alberto Ocaña, Paloma Bragado, Almudena Porras, Alvaro Gutierrez-Uzquiza
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Metastasis is the process of cancer cell dissemination from primary tumors to different organs being the bone the preferred site for metastatic homing of prostate cancer (PCa) cells. Prostate tumorigenesis is a multi-stage process that ultim
Externí odkaz:
https://doaj.org/article/8f492cc077af4106be60cc15dc54728d
Autor:
Michael E. March, Alvaro Gutierrez-Uzquiza, Asbjorg Osk Snorradottir, Leticia S. Matsuoka, Noelia Fonseca Balvis, Thorgeir Gestsson, Kenny Nguyen, Patrick M. A. Sleiman, Charlly Kao, Helgi J. Isaksson, Birkir Thor Bragason, Elias Olafsson, Astridur Palsdottir, Hakon Hakonarson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
HCCAA is a dominantly inherited disease which causes brain hemorrhages as a result of mutant cystatin C aggregation in carriers. Here, the authors show that n- acetyl cysteine can prevent aggregation of mutant protein in a cell model system and rever
Externí odkaz:
https://doaj.org/article/a4b751bc357945ceb32e93795210aa97
Autor:
Isabel Gómez-Redondo, Eva Pericuesta, Paula Navarrete-Lopez, Priscila Ramos-Ibeas, Benjamín Planells, Noelia Fonseca-Balvís, Aida Vaquero-Rey, Raúl Fernández-González, Ricardo Laguna-Barraza, Keiko Horiuchi, Alfonso Gutiérrez-Adán
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103860- (2022)
Summary: ZRSR2 is a splicing factor involved in recognition of 3′-intron splice sites that is frequently mutated in myeloid malignancies and several tumors; however, the role of mutations of Zrsr2 in other tissues has not been analyzed. To explore
Externí odkaz:
https://doaj.org/article/dbc4d6a69a474e8ba5832f984bbeea28
Autor:
Keiko Horiuchi, Serafín Perez-Cerezales, Panagiotis Papasaikas, Priscila Ramos-Ibeas, Angela Patricia López-Cardona, Ricardo Laguna-Barraza, Noelia Fonseca Balvís, Eva Pericuesta, Raul Fernández-González, Benjamín Planells, Alberto Viera, Jose Angel Suja, Pablo Juan Ross, Francisco Alén, Laura Orio, Fernando Rodriguez de Fonseca, Belén Pintado, Juan Valcárcel, Alfonso Gutiérrez-Adán
Publikováno v:
Cell Reports, Vol 23, Iss 1, Pp 143-155 (2018)
Summary: The U2AF35-like ZRSR1 has been implicated in the recognition of 3′ splice site during spliceosome assembly, but ZRSR1 knockout mice do not show abnormal phenotypes. To analyze ZRSR1 function and its precise role in RNA splicing, we generat
Externí odkaz:
https://doaj.org/article/d212e33fab784884b791d952a00bf831
Publikováno v:
Santiago, Vol 0, Iss 0, Pp 190-202 (2017)
This article presents a theoretical reflection on the process of continuous training of university teachers by the constant need to improve the training process, in the search for higher levels of excellence. This process must materialize through pro
Externí odkaz:
https://doaj.org/article/be6d6e0e59fb4f2580f6a63289e69f2f
Autor:
Ismael Lamas-Toranzo, Noelia Fonseca Balvís, Ana Querejeta-Fernández, María José Izquierdo-Rico, Leopoldo González-Brusi, Pedro L Lorenzo, Pilar García-Rebollar, Manuel Avilés, Pablo Bermejo-Álvarez
Publikováno v:
eLife, Vol 8 (2019)
Zona pellucida (ZP), the extracellular matrix sheltering mammalian oocytes and embryos, is composed by 3 to 4 proteins. The roles of the three proteins present in mice have been elucidated by KO models, but the function of the fourth component (ZP4),
Externí odkaz:
https://doaj.org/article/1592c759bb934d9ea36021b6d7dcfbae
Publikováno v:
Maestro y Sociedad, Vol 13, Iss 4, Pp 550-562 (2016)
The University has the challenge to train professionals with a general culture that allows not only successful if not a better quality of life performance. The professional development of teachers together with the need for a constant update appears
Externí odkaz:
https://doaj.org/article/8b50ebb9f9da48dd9fc789dabb28cfa9
Publikováno v:
Medisan, Vol 17, Iss 8, Pp 3018-3022 (2013)
Se realizó un estudio descriptivo y transversal de 25 pacientes con enfermedad de Hansen, atendido en la consulta dermatológica del Policlínico Universitario "Julián Grimau García" del municipio Songo-La Maya, desde enero del 2006 hasta diciembr
Externí odkaz:
https://doaj.org/article/fe4fcc2178e34fc7973b3240b13c0eb8
Autor:
Almudena Porras, Noelia Fonseca, Maria Rodrigo-Faus, Sara Garcia-Garcia, Paloma Bragado, Alvaro Gutierrez-Uzquiza, Balázs Győrffy, Alberto Ocaña, Sara Manzano
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
Metastasis is the process of cancer cell dissemination from primary tumors to different organs being the bone the preferred site for metastatic homing of prostate cancer (PCa) cells. Prostate tumorigenesis is a multi-stage process that ultimately ten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a78cd1853fb3a2be0d0f22e9993e6d3
https://doi.org/10.1038/s41598-021-91292-2
https://doi.org/10.1038/s41598-021-91292-2
Autor:
Priscila Ramos-Ibeas, Noelia Fonseca-Balvís, Keiko Horiuchi, Serafín Pérez-Cerezales, Isabel Gómez-Redondo, Ricardo Laguna-Barraza, Eva Pericuesta, Raúl Fernández, Alfonso Gutiérrez-Adán, Benjamín Planells, Aida Vaquero-Rey
Publikováno v:
SSRN Electronic Journal.
ZRSR2 is a splicing factor essential for 3’ss recognition of U12-type introns and is frequently mutated in myeloid malignancies and in several tumors. To explore the biological role of ZRSR2 we generated three Zrsr2 mutant mice with deletions local
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::916158fc74f6d64ab4ee1ff2c6a14257
https://doi.org/10.2139/ssrn.3844736
https://doi.org/10.2139/ssrn.3844736