Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Noelene Sheila Quinsey"'
Autor:
Andrew G. Allen, Gerald L. Murray, Deanna Deveson Lucas, Dieter M. Bulach, Noelene Sheila Quinsey, Ben Adler, Miranda Lo
Publikováno v:
Veterinary Microbiology. 169:163-170
Leptospira borgpetersenii serovar Hardjo subtype Hardjobovis (Hardjobovis) is the main causative agent of bovine leptospirosis in Australia, New Zealand, North America and elsewhere. Bovine leptospirosis can result in spontaneous abortion, stillbirth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2699002a225b494d4314766f32f25236
https://doi.org/10.1016/j.vetmic.2013.12.016
https://doi.org/10.1016/j.vetmic.2013.12.016
Publikováno v:
International journal of medical microbiology : IJMM. 306(6)
Clostridium perfringens is a Gram-positive, anaerobic, spore-forming bacterium that causes human gas gangrene (clostridial myonecrosis) and food poisoning. Early studies showed that virulence was regulated by the VirSR two-component signal transducti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c5087afeb237f4ac4807d95bbd21d03
https://pubmed.ncbi.nlm.nih.gov/27267179
https://pubmed.ncbi.nlm.nih.gov/27267179
Autor:
Radhika Bantwal, Corrine Joy Porter, Dena Lyras, Trudi L. Bannam, Victoria Michelle Adams, Noelene Sheila Quinsey, Julian I. Rood
Publikováno v:
Plasmid. 67:139-147
Peptidoglycan hydrolases that are specifically associated with bacterial conjugation systems are postulated to facilitate the assembly of the transfer apparatus by creating a temporally and spatially controlled local opening in the peptidoglycan laye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5738d8a93e172a4066495c606ae75f4
https://doi.org/10.1016/j.plasmid.2011.12.016
https://doi.org/10.1016/j.plasmid.2011.12.016
Autor:
Philip E. Thompson, Phillip I. Bird, Antony Yaron Matthews, Dion Kaiserman, Noelene Sheila Quinsey, Lakshmi C. Wijeyewickrema, Natasha May-Yoke Ng, Robert N. Pike
Publikováno v:
Archives of Biochemistry and Biophysics. 489:48-54
Thrombin (EC 3.4.4.13) has two exosites that mediate interactions between the enzyme and its substrates and cofactors. The binding of ligands to the exosites alters the functions of the protease, for example, when the cofactor thrombomodulin binds to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03b35d9cfccc73659092ccd91187d878
https://doi.org/10.1016/j.abb.2009.07.012
https://doi.org/10.1016/j.abb.2009.07.012
Autor:
Terence W Spithill, Peter M. Smooker, Deanne L.V. Greenwood, Ruby H. P. Law, Carolyn I Phillips, Robert N. Pike, Nirma Samarawickrema, Lakshmi C. Wijeyewickrema, Boris Turk, David Piedrafita, Noelene Sheila Quinsey, Theresa H.T. Coetzer, James A. Irving, Matthew Bogyo, Steven H. L. Verhelst, Simone A. Beckham
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 41:1601-1612
The newly excysted juvenile (NEJ) stage of the Fasciola hepatica lifecycle occurs just prior to invasion into the wall of the gut of the host, rendering it an important target for drug development. The cathepsin B enzymes from NEJ flukes have recentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8c35df2910ab0b877d8d0a293a66d92
https://doi.org/10.1016/j.biocel.2009.02.003
https://doi.org/10.1016/j.biocel.2009.02.003
Autor:
Rebecca E. Fitzpatrick, Robert N. Pike, Noelene Sheila Quinsey, James Travis, Aneta Sroka, Jan Potempa, Adrian Dale McAlister
Publikováno v:
Journal of Periodontal Research. 44:348-353
Background and Objective: Porphyromonas gingivalis, an anaerobic bacterium associated with adult periodontal disease, employs a number of pathogenic mechanisms, including protease/adhesin complexes (gingipains), fimbriae and hemagglutinins, to mainta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad478daa45a64fd17b2718926bc3ab89
https://doi.org/10.1111/j.1600-0765.2008.01128.x
https://doi.org/10.1111/j.1600-0765.2008.01128.x
Autor:
Noelene Sheila Quinsey, Ruby H-P Law, Simone A. Beckham, Robert N. Pike, James H. McKerrow, Conor R. Caffrey, Terence W Spithill, Peter M. Smooker
Publikováno v:
Biological Chemistry. 387:1053-1061
The liver fluke,Fasciola hepatica, apparently uses a number of cysteine proteases during its life cycle, most likely for feeding, immune evasion and invasion of tissues. A cathepsin B-like enzyme (herein referred to as FhcatB1) appears to be a major
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bea1c07520089990c6d55d76153e27f2
https://doi.org/10.1515/bc.2006.130
https://doi.org/10.1515/bc.2006.130
Publikováno v:
Chemical Biology Drug Design. 68:11-19
Inhibitors of procoagulant enzymes, such as factor Xa (fXa) and thrombin, are important for treating thrombosis. Thrombin has complex pro- and anti-coagulant roles and thus fXa is thought to represent an ideal target. Discrete kcat and Km values for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42595a106b9e1fe06bd8a4cd6f032e45
https://doi.org/10.1111/j.1747-0285.2006.00404.x
https://doi.org/10.1111/j.1747-0285.2006.00404.x
Autor:
Stephen P. Bottomley, Noelene Sheila Quinsey, Robert N. Pike, Anita J Horvath, James C. Whisstock, Jamie Rossjohn, Paul Bernard Coughlin, James A. Irving, Ruby H. P. Law
Publikováno v:
Journal of Biological Chemistry. 280:43168-43178
Antichymotrypsin (SERPINA3) is a widely expressed member of the serpin superfamily, required for the regulation of leukocyte proteases released during an inflammatory response and with a permissive role in the development of amyloid encephalopathy. D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90801d69ef49c1d14cf73cdaeaf5e637
https://doi.org/10.1074/jbc.m505598200
https://doi.org/10.1074/jbc.m505598200
Autor:
James C. Whisstock, Phillip I. Bird, Felicity Kate Kerr, Dion Kaiserman, Sarah Elizabeth Boyd, Maria Garcia de la Banda, Antony Yaron Matthews, Noelene Sheila Quinsey, Robert N. Pike, Grace O'Brien
Publikováno v:
Journal of Biological Chemistry. 280:39510-39514
The complement system is a central component of host defense but can also contribute to the inflammation seen in pathological conditions. The C1s protease of the first complement component, the C1 complex, initiates the pathway. In this study we have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c063921d8bc4b63c1e93bddf91ab43f1
https://doi.org/10.1074/jbc.m506131200
https://doi.org/10.1074/jbc.m506131200