Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Noel T Pauli"'
Autor:
Kaval Kaur, Nai-Ying Zheng, Kenneth Smith, Min Huang, Lie Li, Noel T Pauli, Carole J Henry Dunand, Jane-Hwei Lee, Michael Morrissey, Yixuan Wu, Michelle L Joachims, Melissa E Munroe, Denise Lau, Xinyan Qu, Florian Krammer, Jens Wrammert, Peter Palese, Rafi Ahmed, Judith A James, Patrick C Wilson
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125618 (2015)
Breakdown of B cell tolerance is a cardinal feature of systemic lupus erythematosus (SLE). Increased numbers of autoreactive mature naïve B cells have been described in SLE patients and autoantibodies have been shown to arise from autoreactive and n
Externí odkaz:
https://doaj.org/article/af56636f00884a63a7d502d8b7d8e932
Autor:
Olivia S. Shin, Stephanie R. Monticelli, Christy K. Hjorth, Vladlena Hornet, Michael Doyle, Dafna Abelson, Ana I. Kuehne, Albert Wang, Russell R. Bakken, Akaash K. Mishra, Marissa Middlecamp, Elizabeth Champney, Lauran Stuart, Daniel P. Maurer, Jiannan Li, Jacob Berrigan, Jennifer Barajas, Stephen Balinandi, Julius J. Lutwama, Leslie Lobel, Larry Zeitlin, Laura M. Walker, John M. Dye, Kartik Chandran, Andrew S. Herbert, Noel T. Pauli, Jason S. McLellan
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114502- (2024)
Summary: Crimean-Congo hemorrhagic fever virus can cause lethal disease in humans yet there are no approved medical countermeasures. Viral glycoprotein GP38, exclusive to Nairoviridae, is a target of protective antibodies and is a key antigen in prec
Externí odkaz:
https://doaj.org/article/d783005edd1a4330be69737cbfd33c17
Autor:
John M. Dye, Leslie Lobel, Zachary A. Bornholdt, Thomas W. Geisbert, Laura M. Walker, Robert W. Cross, Kartik Chandran, J. Maximilian Fels, Daniel P. Maurer, Dafna M. Abelson, Noel T. Pauli, Andrew S. Herbert, Ana I. Kuehne
Publikováno v:
Proceedings, Vol 50, Iss 128, p 128 (2020)
Crimean–Congo hemorrhagic fever virus (CCHFV) is an arbovirus belonging to the Nairoviridae family. The virus, as well as ticks of the Hyalomma genus, which serve as its reservoir host, are found in parts of Africa, western Asia, and southern Europ
Publikováno v:
Antioxidants & Redox Signaling. 22:785-796
Aims: Plants employ both basal and resistance gene (R gene)-mediated defenses in response to pathogens. Reactive oxygen species (ROS) are widely reported to play a central role in both basal and R gene-mediated defense; however, the nature of ROS has
Publikováno v:
Journal of Virology. 89:3308-3317
Reactivation of memory B cells allows for a rapid and robust immune response upon challenge with the same antigen. Variant influenza virus strains generated through antigenic shift or drift are encountered multiple times over the lifetime of an indiv
Autor:
Sarah F. Andrews, Olaf Schneewind, Kaval Kaur, Yunping Huang, Fabiana Falugi, Nai-Ying Zheng, Noel T. Pauli, Patrick C. Wilson, Karen M. Frank, Min Huang, John Dulac, Andrea C. DeDent, Carole J. Henry Dunand, Angella Charnot-Katsikas, Hwan Keun Kim
Publikováno v:
The Journal of Experimental Medicine
Pauli et al. find that the active B cell response in patients infected with Staphylococcus aureus is predominately focused on a single antigen, SpA, which acts as a B cell superantigen. SpA-reactive antibodies dominate the response despite the presen
Autor:
William Taylor, Peter Palese, Noel T. Pauli, Carole J. Henry Dunand, Sarah F. Andrews, Jane-Hwei Lee, Min Huang, Marlene Salgado-Ferrer, Rafi Ahmed, Kaval Kaur, Florian Krammer, Yunping Huang, Patrick C. Wilson, Lyubov I. Popova, Jens Wrammert, Irvin Y. Ho, Samuel Lim, Xinyan Qu
Publikováno v:
Science translational medicine. 7(316)
Generating a broadly protective influenza vaccine is critical to global health. Understanding how immune memory influences influenza immunity is central to this goal. We undertook an in-depth study of the B cell response to the pandemic 2009 H1N1 vac
Autor:
Noel T. Pauli, Peter Palese, Carole J. Henry Dunand, Kaval Kaur, Kenneth J. Smith, Min Huang, Michelle L. Joachims, Xinyan Qu, Florian Krammer, Rafi Ahmed, Patrick C. Wilson, Yixuan Wu, Jens Wrammert, Jane-Hwei Lee, Melissa E. Munroe, Li L, Denise Lau, Nai-Ying Zheng, Michael Morrissey, Judith A. James
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125618 (2015)
Breakdown of B cell tolerance is a cardinal feature of systemic lupus erythematosus (SLE). Increased numbers of autoreactive mature naïve B cells have been described in SLE patients and autoantibodies have been shown to arise from autoreactive and n
Publikováno v:
F1000 Biology Reports
Monoclonal antibody technology has undergone rapid and innovative reinvention over the last 30 years. Application of these technologies to human samples revealed valuable therapeutic and experimental insights. These technologies, each with their own
Autor:
J. Maximilian Fels, Daniel Maurer, Ana I. Kuehne, Dafna M. Abelson, Noel T. Pauli, Andrew S. Herbert, John M. Dye, Robert W. Cross, Thomas W. Geisbert, Leslie Lobel, Zachary A. Bornholdt, Laura M. Walker, Kartik Chandran
Publikováno v:
Proceedings, Vol 50, Iss 1, p 128 (2020)
Crimean–Congo hemorrhagic fever virus (CCHFV) is an arbovirus belonging to the Nairoviridae family. The virus, as well as ticks of the Hyalomma genus, which serve as its reservoir host, are found in parts of Africa, western Asia, and southern Europ
Externí odkaz:
https://doaj.org/article/129f5e95287e41dd9f8bb59f5da075f5