Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Noel Roberts"'
Publikováno v:
BMC Medical Education, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background The use of feedback has been integral to medical student learning, but rigorous evidence to evaluate its education effect is limited, especially in the role of patient feedback in clinical teaching and practice improvement. The ai
Externí odkaz:
https://doaj.org/article/dc606f266ac145c7b217f0ac30d354fb
Autor:
Malcolm Baxter, Gillian M. Nixon, David Stuart Armstrong, Sarah Arachchi, Sarah McLeod, Margot J Davey, Noel Roberts
Publikováno v:
International Journal of Pediatric Otorhinolaryngology. 82:54-57
Background In 2012 clinical management of children having adenotonsillectomy (AT) for suspected obstructive sleep apnea (OSA) at our tertiary centre changed based on previous research: children with severe obstructive sleep apnea (OSA) at increased r
Autor:
Noel Roberts
Publikováno v:
New Blackfriars. 88:56-66
Publikováno v:
Journal of Antimicrobial Chemotherapy. 51:977-990
A mathematical model of influenza transmission dynamics is used to simulate the impact of neuraminidase inhibitor therapy on infection rates and transmission of drug-resistant viral strains. The model incorporates population age structure, seasonal t
Autor:
Noel Roberts, Christian Gilbert, Rebecca Sudlow, Guy Boivin, Annie Gaudreau, Isobel Greenfield
Publikováno v:
The Journal of Infectious Diseases. 184:1598-1602
The emergence of mutations conferring ganciclovir resistance was evaluated in an open-label randomized clinical trial that compared oral valganciclovir with intravenous ganciclovir as induction therapy, followed by maintenance with valganciclovir, fo
Publikováno v:
Clinical Drug Investigation. 20:447-454
In most years epidemics of influenza cause a significant increase in morbidity and mortality worldwide. With the availability of a new class of antivirals targeting the viral protein neuraminidase, there are new options for the control of influenza.
Autor:
Helmut Jacobsen, Ludwina Ahlborn-Laake, Ralf Bartenschlager, Pascal Bouffard, Noel Roberts, Jan Mous
Publikováno v:
Virology. 209(1):52-59
Hepatitis C virus (HCV) encodes a polyprotein of which the majority of nonstructural proteins are matured by the viral serine proteinase located in the N terminus of NS3. Intracellular studies using recombinant vaccinia virus have shown that both NS3
Publikováno v:
Antiviral therapy. 12(4 Pt)
Oseltamivir phosphate is a prodrug of oseltamivir carboxylate, a highly specific inhibitor of influenza virus neuraminidases. Given that oseltamivir carboxylate binds to highly conserved, essential amino acids in the catalytic site of the enzyme, and
Autor:
David Ipe, Graham McClelland, Gilbert Schiff, Noel Roberts, Lance C. Jennings, Brinderjeet Rana, Helen C. Jackson, Frederick G. Hayden, Penelope Ward, Richard A. Robson
Publikováno v:
Antiviral therapy. 5(3)
Oseltamivir is the prodrug of Ro64-0802 (GS4071), a potent and selective inhibitor of influenza A and B virus neuraminidases. Three randomized, double-blind, placebo-controlled, parallel-group studies evaluated oral oseltamivir for early treatment (7
Autor:
Noel Roberts
Publikováno v:
New Blackfriars. 55:461-469