Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Noel Lenny"'
Autor:
Anami Patel, Kacy A Ramirez, John P. DeVincenzo, Noel Lenny, Rebecca E. Thompson, Nancy Clanton Watson, Asim F. Choudhri, Leslie Berkelhammer Greenberg, Mehmet Kocak
Publikováno v:
Journal of Clinical Virology. 107:29-37
Background Herpes Simplex Virus encephalitis (HSVE) is a devastating disease of all ages. Rigorous studies correlating viral load with neuroradiological and clinical severity have not been performed, particularly in neonates. Understanding these rela
Autor:
Noel Lenny, Wesley H. Self, Anami Patel, Seema Jain, Evan J. Anderson, Senthilkumar K. Sakthivel, Amber K. Haynes, Yuwei Zhu, Chao Qi, Richard G. Wunderink, Sandra R. Arnold, Dean D. Erdman, Carlos G. Grijalva, Anna M. Bramley, David R. Hillyard, Weston Hymas, Andrew T. Pavia, Kathryn M. Edwards, Jonathan A. McCullers, Krow Ampofo, Yange Zhang, James D. Chappell, Derek J. Williams
Publikováno v:
Journal of Clinical Microbiology. 55:79-89
Both molecular and serological assays have been used previously to determine the etiology of community-acquired pneumonia (CAP). However, the extent to which these methods are correlated and the added diagnostic value of serology for respiratory viru
Autor:
Anami Patel, Ishita Pareek, Kacy A Ramirez, John P. DeVincenzo, Carson House, Rebecca Thompson, Noel Lenny
Publikováno v:
Clinical Microbiology: Open Access.
Polymerase chain reaction (PCR) is the gold-standard for diagnosing HSVE, but may be inhibited by blood contamination. We mimicked traumatic lumbar puncture and measured its effect on the molecular detection of HSV-1 in CSF. Clinically meaningful red
Autor:
Seema Jain, Derek J. Williams, Sandra R. Arnold, Krow Ampofo, Anna M. Bramley, Carrie Reed, Chris Stockmann, Evan J. Anderson, Carlos G. Grijalva, Wesley H. Self, Yuwei Zhu, Anami Patel, Weston Hymas, James D. Chappell, Robert A. Kaufman, J. Herman Kan, David Dansie, Noel Lenny, David R. Hillyard, Lia M. Haynes, Min Levine, Stephen Lindstrom, Jonas M. Winchell, Jacqueline M. Katz, Dean Erdman, Eileen Schneider, Lauri A. Hicks, Richard G. Wunderink, Kathryn M. Edwards, Andrew T. Pavia, Jonathan A. McCullers, Lyn Finelli
Publikováno v:
New England Journal of Medicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a7275d5cb5dfd2a0d133ed6fbc08a92
https://europepmc.org/articles/PMC4697461/
https://europepmc.org/articles/PMC4697461/
Publikováno v:
Blood. 103:2522-2529
The Runx1/core binding factor-β (CBFβ) transcriptional complex is required for the establishment of hematopoiesis during development. Despite its critical role during development, a detailed analysis of Runx1 expression within specific lineages and
Autor:
Guangchun Song, Sheila A. Shurtleff, Hsi Che Liu, Xiaodong Zhou, Susana C. Raimondi, Anami Patel, Kevin Girtman, W. Kent Williams, Noel Lenny, James R. Downing, Mary E. Ross, Rami Mahfouz
Publikováno v:
Blood. 102:2951-2959
Contemporary treatment of pediatric acute lymphoblastic leukemia (ALL) requires the assignment of patients to specific risk groups. We have recently demonstrated that expression profiling of leukemic blasts can accurately identify the known prognosti
Autor:
Darin P. O’Brien, Noel Lenny, Parasakthy Kumaravelu, Eng-Juh Yeoh, James R. Downing, Masakazu Higuchi
Publikováno v:
Cancer Cell. 1:63-74
The AML1/CBFβ transcription factor complex, a frequent target of chromosomal translocations in leukemia, is essential for the generation of definitive hematopoietic stem cells. Paradoxically, expression of the acute myeloid leukemia-associated AML1-
Autor:
James R. Downing, Hironori Harada, Shari Meyers, Noel Lenny, John Nip, Bart Lutterbach, Scott W. Hiebert, David K. Strom, Joseph M. Amann
Publikováno v:
Molecular and Cellular Biology. 21:6470-6483
t(8;21) and t(16;21) create two fusion proteins, AML-1-ETO and AML-1-MTG16, respectively, which fuse the AML-1 DNA binding domain to putative transcriptional corepressors, ETO and MTG16. Here, we show that distinct domains of ETO contact the mSin3A a
Autor:
Christine C. Ginocchio, Margaret Vossinas, Kathleen M. Todd, John P. DeVincenzo, Xiaotian Zheng, Anami Patel, Ryhana Manji, Angela Drain, Malgorzata Kowerska, Noel Lenny
Publikováno v:
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology. 60(2)
Background Adenoviruses (AdV) cause a variety of upper and lower respiratory tract infections, with the potential for severe outcomes, especially in persons with immune suppression or other underlying diseases. The ADENOVIRUS US R-gene (AdV R-gene, A
Publikováno v:
Seminars in Cell & Developmental Biology. 11:347-360
The identification of clonal chromosomal translocations in human leukemias provided one of the first insights into the underlying pathogenesis of this clinically heterogeneous disease. Over the last decade a large number of these chromosomal rearrang