Výsledky vyhledávání - "Noel G, McElvaney"

Akademický článek

Sex differences in airway disease: estrogen and airway surface liquid dynamics

Autor: Brian J. Harvey, Noel G. McElvaney

Publikováno v: Biology of Sex Differences, Vol 15, Iss 1, Pp 1-30 (2024)

Abstract Biological sex differences exist for many airway diseases in which females have either worse or better health outcomes. Inflammatory airway diseases such as cystic fibrosis (CF) and asthma display a clear male advantage in post-puberty while

Externí odkaz: https://doaj.org/article/863c57857957482596c0faa05c39f78a

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Akademický článek

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In recognition of Ireland's clinical medical researchers: Noel G McElvaney, T Joseph McKenna, Noel Caplice and Bryan Hennessy

Autor: William Tormey

Publikováno v: Irish journal of medical science. 187(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97883bde75677acd2144ea2ecd2a7ad0
https://pubmed.ncbi.nlm.nih.gov/29368280

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Akademický článek

"Blood basophil activation is a reliable biomarker of allergic bronchopulmonary aspergillosis in cystic fibrosis." Yael Gernez, Jeffrey Waters, Bojana Mirković, Gillian M. Lavelle, Colleen E. Dunn, Zoe A. Davies, Cassie Everson, Rabindra Tirouvanziam, Elana Silver, Sylvan Wallenstein, Sanjay H. Chotirmall, Noel G. McElvaney, Leonore A. Herzenberg and Richard B. Moss. Eur Respir J 2016; 47: 177-185.

Publikováno v: The European respiratory journal [Eur Respir J] 2016 Jun; Vol. 47 (6), pp. 1892.

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Akademický článek

Altered Serum Alpha1-Antitrypsin Protease Inhibition before and after Clinical Hematopoietic Stem Cell Transplantation: Association with Risk for Non-Relapse Mortality

Autor: Ido Brami, Tsila Zuckerman, Ron Ram, Batia Avni, Galit Peretz, Daniel Ostrovsky, Yotam Lior, Caroline Faour, Oisin McElvaney, Noel G. McElvaney, Eli C. Lewis

Publikováno v: International Journal of Molecular Sciences, Vol 25, Iss 1, p 422 (2023)

α1-Antitrypsin (AAT), an acute-phase reactant not unsimilar to C-reactive protein (CRP), is a serine protease inhibitor that harbors tissue-protective and immunomodulatory attributes. Its concentrations appropriately increase during conditions of ex

Externí odkaz: https://doaj.org/article/06a97daf5c92472e935ac2178e4a0801

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'Blood basophil activation is a reliable biomarker of allergic bronchopulmonary aspergillosis in cystic fibrosis.' Yael Gernez, Jeffrey Waters, Bojana Mirković, Gillian M. Lavelle, Colleen E. Dunn, Zoe A. Davies, Cassie Everson, Rabindra Tirouvanziam, Elana Silver, Sylvan Wallenstein, Sanjay H. Chotirmall, Noel G. McElvaney, Leonore A. Herzenberg and Richard B. Moss. Eur Respir J 2016; 47: 177-185

Autor: Richard Moss, Noel Mcelvaney, Sanjay Haresh Chotirmall, Rabindra Tirouvanziam

Publikováno v: The European respiratory journal. 47(6)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c8ddae1f19dc97386fc5022970886f
https://pubmed.ncbi.nlm.nih.gov/26585435

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Akademický článek

Diagnostic agreement among experts assessing adults presenting with possible cystic fibrosis: need for improvement and implications for patient care

Autor: Alessandro N. Franciosi, April Tanzler, Jodi Goodwin, Pearce G. Wilcox, George M. Solomon, Albert Faro, Noel G. McElvaney, Damian G. Downey, Bradley S. Quon

Publikováno v: ERJ Open Research, Vol 8, Iss 4 (2022)

Background Increasing awareness of milder presentations of cystic fibrosis (CF) and greater interest in non-CF bronchiectasis are likely to lead to more CF screening by respiratory clinicians. As a result, adults who may not strictly fulfil CF diagno

Externí odkaz: https://doaj.org/article/6f617089f9e54fb9bd7aabebc4efc679

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Akademický článek

Prone positioning improves oxygenation and lung recruitment in patients with SARS-CoV-2 acute respiratory distress syndrome; a single centre cohort study of 20 consecutive patients

Autor: Jennifer Clarke, Pierce Geoghegan, Natalie McEvoy, Maria Boylan, Orna Ní Choileáin, Martin Mulligan, Grace Hogan, Aoife Keogh, Oliver J. McElvaney, Oisín F. McElvaney, John Bourke, Bairbre McNicholas, John G. Laffey, Noel G. McElvaney, Gerard F. Curley

Publikováno v: BMC Research Notes, Vol 14, Iss 1, Pp 1-6 (2021)

Abstract Objective We aimed to characterize the effects of prone positioning on respiratory mechanics and oxygenation in invasively ventilated patients with SARS-CoV-2 ARDS. Results This was a prospective cohort study in the Intensive Care Unit (ICU)

Externí odkaz: https://doaj.org/article/94a79657b32f4c889115ec3f9fe0ca2d

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Protease-anti-protease compartmentalization in SARS-CoV-2 ARDS: Therapeutic implications

Publikováno v: EBioMedicine, Vol 77, Iss , Pp 103894- (2022)

Summary: Background: Interleukin-6 (IL-6) is elevated in SARS-CoV-2 infection. IL-6 regulates acute-phase proteins, such as alpha-1 antitrypsin (AAT), a key lung anti-protease. We investigated the protease-anti-protease balance in the circulation and

Externí odkaz: https://doaj.org/article/8689f1b6c49645dc94c1c385411f7c38

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Akademický článek

In vitro and in vivo modulation of NADPH oxidase activity and reactive oxygen species production in human neutrophils by α1-antitrypsin

Autor: Padraig Hawkins, Thomas McEnery, Claudie Gabillard-Lefort, David A. Bergin, Bader Alfawaz, Vipatsorn Shutchaidat, Paula Meleady, Michael Henry, Orla Coleman, Mark Murphy, Noel G. McElvaney, Emer P. Reeves

Publikováno v: ERJ Open Research, Vol 7, Iss 4 (2021)

Oxidative stress from innate immune cells is a driving mechanism that underlies COPD pathogenesis. Individuals with α-1 antitrypsin (AAT) deficiency (AATD) have a dramatically increased risk of developing COPD. To understand this further, the aim of

Externí odkaz: https://doaj.org/article/af089efb2deb4f1abed964d43721db1d

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