Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Noe Rodriguez Rodriguez"'
Autor:
Paula A. Clark, Mayuri Gogoi, Noe Rodriguez-Rodriguez, Ana C. F. Ferreira, Jane E. Murphy, Jennifer A. Walker, Alastair Crisp, Helen E. Jolin, Jacqueline D. Shields, Andrew N. J. McKenzie
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Innate lymphoid cells (ILCs) are critical in maintaining tissue homeostasis, and during infection and inflammation. Here we identify, by using combinatorial reporter mice, a rare ILC progenitor (ILCP) population, resident to the small intest
Externí odkaz:
https://doaj.org/article/c71615789fe8474da7ea50ebd878945a
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Colorectal cancer (CRC) is the second leading cause of cancer-related death worldwide, and is largely refractory to current immunotherapeutic interventions. The lack of efficacy of existing cancer immunotherapies in CRC reflects the complex nature of
Externí odkaz:
https://doaj.org/article/b538b4fca4d94628bc9851ad26690b39
Autor:
Noe Rodriguez-Rodriguez, Paula A. Clark, Mayuri Gogoi, Ana C. F. Ferreira, Bernhard Kerscher, Alastair Crisp, Helen E. Jolin, Jane E. Murphy, Meera Sivasubramaniam, Luisa Pedro, Jennifer A. Walker, Morgan W. D. Heycock, Jacqueline D. Shields, Jillian L. Barlow, Andrew N. J. McKenzie
Peer reviewed: True
The development of innate lymphoid cell (ILC) transcription factor reporter mice has shown a previously unexpected complexity in ILC hematopoiesis. Using novel polychromic mice to achieve higher phenotypic resolution, we have
The development of innate lymphoid cell (ILC) transcription factor reporter mice has shown a previously unexpected complexity in ILC hematopoiesis. Using novel polychromic mice to achieve higher phenotypic resolution, we have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9abacda08a781806bece8f560aff401
Autor:
Eric Jou, Noe Rodriguez-Rodriguez, Ana-Carolina F. Ferreira, Helen E. Jolin, Paula A. Clark, Kovilen Sawmynaden, Michelle Ko, Jane E. Murphy, Jonathan Mannion, Christopher Ward, David J. Matthews, Simon J. A. Buczacki, Andrew N. J. McKenzie
Publikováno v:
Science Immunology
Interleukin-25 (IL-25) and group 2 innate lymphoid cells (ILC2s) defend the host against intestinal helminth infection and are associated with inappropriate allergic reactions. IL-33–activated ILC2s were previously found to augment protective tissu
Autor:
Hao Li, George C. Tsokos, Pui Lee, Amir Sharabi, Michihito Kono, Maria Tsokos, Esra Meidan, John P. Manis, Vasileios C. Kyttaris, José C. Crispín, Christina Ioannidis, Sokratis A. Apostolidis, Shuilian Yu, Wen Liang Pan, Noe Rodriguez Rodriguez
Publikováno v:
JCI Insight. 5
Protein phosphatase 2A (PP2A), a serine/threonine phosphatase, has been shown to control T cell function. We found that in vitro–activated B cells and B cells from various lupus-prone mice and patients with systemic lupus erythematosus display incr
Autor:
George C. Tsokos, José C. Crispín, Noe Rodriguez Rodriguez, Christina Ioannidis, Vasileios C. Kyttaris, Alexandros P. Grammatikos, Thomas Rauen, Christian M. Hedrich, Sokratis A. Apostolidis
Publikováno v:
Proceedings of the National Academy of Sciences. 111:13457-13462
The immune-regulatory cytokine IL-10 plays a central role during innate and adaptive immune responses. IL-10 is elevated in the serum and tissues of patients with systemic lupus erythematosus (SLE), an autoimmune disorder characterized by autoantibod
Autor:
Christina Ioannidis, Tomohiro Koga, Thomas Rauen, Sokratis A. Apostolidis, Noe Rodriguez Rodriguez, José C. Crispín, Christian M. Hedrich, Vasileios C. Kyttaris, George C. Tsokos
Publikováno v:
Journal of Biological Chemistry. 289:2361-2370
TCR-αβ(+)CD3(+)CD4(-)CD8(-) "double negative" T cells are expanded in the peripheral blood of patients with systemic lupus erythematosus (SLE) and lupus-prone mice. Double negative T cells have been claimed to derive from CD8(+) cells that down-reg
Autor:
Noe Rodriguez-Rodriguez, Sokratis Apostolidis, Tran Nguyen, Jose Martin Villa, George Tsokos, Jose Crispin
Publikováno v:
The Journal of Immunology. 192:113.3-113.3
The ontogeny and raison d'être of peripheral TCR-αβ+CD3+CD4-CD8- T cells, henceforth “DN T cells”, remain controversial. They represent a small population within the bulk of peripheral T cells that expands in certain inflammatory conditions su