Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Noe B Mercado"'
Autor:
Daniel Y Zhu, Matthew J Gorman, Dansu Yuan, Jingyou Yu, Noe B Mercado, Katherine McMahan, Erica N Borducchi, Michelle Lifton, Jinyan Liu, Felix Nampanya, Shivani Patel, Lauren Peter, Lisa H Tostanoski, Laurent Pessaint, Alex Van Ry, Brad Finneyfrock, Jason Velasco, Elyse Teow, Renita Brown, Anthony Cook, Hanne Andersen, Mark G Lewis, Douglas A Lauffenburger, Dan H Barouch, Galit Alter
Publikováno v:
PLoS Biology, Vol 20, Iss 5, p e3001609 (2022)
Despite the rapid creation of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) vaccines, the precise correlates of immunity against severe Coronavirus Disease 2019 (COVID-19) are still unknown. Neutralizing antibodies represent a robust s
Externí odkaz:
https://doaj.org/article/4d1be3554a1648f7a95b8e4694bcb0af
Autor:
Noe B. Mercado, Jacqueline N. Real, Jacob Kaiserman, Eleni Panagioti, Charles H. Cook, Sean E. Lawler
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-11 (2024)
Abstract Glioblastoma (GBM) is one of the deadliest brain cancers with a median survival of only 15 months. This poor prognosis has prompted exploration of novel therapeutic targets for GBM patients. Human cytomegalovirus (HCMV) has been implicated i
Externí odkaz:
https://doaj.org/article/018f7697d6444b4abc5f1b05d01732e2
Autor:
Victoria E. K. Walker-Sperling, Noe B. Mercado, Abishek Chandrashekar, Erica N. Borducchi, Jinyan Liu, Joseph P. Nkolola, Mark Lewis, Jeffrey P. Murry, Yunling Yang, Romas Geleziunas, Merlin L. Robb, Nelson L. Michael, Maria G. Pau, Frank Wegmann, Hanneke Schuitemaker, Emily J. Fray, Mithra R. Kumar, Janet D. Siliciano, Robert F. Siliciano, Dan H. Barouch
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
Antiretroviral therapy alone is insufficient in curing HIV-1 infection, due to latent viral reservoir persistency. Here, authors explore the post-virologic control of combining active and passive immunisation with vesatolimod, in a SHIV-infected rhes
Externí odkaz:
https://doaj.org/article/3d61c11904ca4bafb0acb1d4d9eb6212
Autor:
Ramon Roozendaal, Laura Solforosi, Daniel J. Stieh, Jan Serroyen, Roel Straetemans, Anna Dari, Muriel Boulton, Frank Wegmann, Sietske K. Rosendahl Huber, Joan E. M. van der Lubbe, Jenny Hendriks, Mathieu Le Gars, Liesbeth Dekking, Dominika N. Czapska-Casey, Nuria Guimera, Sarah Janssen, Sarah Tete, Abishek Chandrashekar, Noe B. Mercado, Jingyou Yu, Wouter Koudstaal, Juan J. Perez-Ruixo, Jerry Sadoff, Dan H. Barouch, Hanneke Schuitemaker, Roland Zahn
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Several COVID-19 vaccines have received emergency approval, but durability of protection is unclear. Here, the authors describe correlates of protection (CoP) for the Ad26.COV2.S vaccine in rhesus macaques and report that CoP predict the protection o
Externí odkaz:
https://doaj.org/article/c77c130d228d404b88e0e8b1e5e20f78
Autor:
Anthony M. Cadena, John D. Ventura, Peter Abbink, Erica N. Borducchi, Hubert Tuyishime, Noe B. Mercado, Victoria Walker-Sperling, Mazuba Siamatu, Po-Ting Liu, Abishek Chandrashekar, Joseph P. Nkolola, Katherine McMahan, Nicole Kordana, Venous Hamza, Esther A. Bondzie, Emily Fray, Mithra Kumar, Stephanie Fischinger, Sally A. Shin, Mark G. Lewis, Robert F. Siliciano, Galit Alter, Dan H. Barouch
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
The existence of HIV reservoir and ongoing replication despite antiretroviral therapy (ART) represents a barrier for cure efforts. Here, using SIV/SHIV-infected rhesus macaque suppressed with ART for one year, the authors characterize multiple lympho
Externí odkaz:
https://doaj.org/article/202e143cd50c4ecea53a829693bdf039
Autor:
Po-Ting Liu, Brandon F. Keele, Peter Abbink, Noe B. Mercado, Jinyan Liu, Esther A. Bondzie, Abishek Chandrashekar, Erica N. Borducchi, Joseph Hesselgesser, Michael Mish, Gregory Chin, Elena Bekerman, Romas Geleziunas, Dan H. Barouch
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
The origin and nature of rebound HIV-1 virus following antiretroviral therapy (ART) discontinuation still remains unclear. Here, Liu et al. suggest that intact proviral DNA in peripheral blood and lymph node mononuclear cells during ART suppression l
Externí odkaz:
https://doaj.org/article/4bcf043d109d4ee280c833a2bd8a8741
Autor:
Raja Mohan Gopalakrishnan, Malika Aid, Noe B. Mercado, Caitlin Davis, Shaily Malik, Emma Geiger, Valerie Varner, Rhianna Jones, Steven E. Bosinger, Cesar Piedra-Mora, Amanda J. Martinot, Dan H. Barouch, R. Keith Reeves, C. Sabrina Tan
Publikováno v:
JCI Insight, Vol 6, Iss 20 (2021)
Knowledge of immune activation in the brain during acute HIV infection is crucial for the prevention and treatment of HIV-associated neurological disorders. We determined regional brain (basal ganglia, thalamus, and frontal cortex) immune and virolog
Externí odkaz:
https://doaj.org/article/a869258e8da0486a85f240faebc9c307
Autor:
Cesar Piedra-Mora, Sally R. Robinson, Lisa H. Tostanoski, Denise A. E. Dayao, Abishek Chandrashekar, Katherine Bauer, Linda Wrijil, Sarah Ducat, Tammy Hayes, Jingyou Yu, Esther A. Bondzie, Katherine McMahan, Daniel Sellers, Victoria Giffin, David Hope, Felix Nampanya, Noe B. Mercado, Swagata Kar, Hanne Andersen, Saul Tzipori, Dan H. Barouch, Amanda J. Martinot
Publikováno v:
Veterinary Pathology. 59:648-660
There is a need to standardize pathologic endpoints in animal models of SARS-CoV-2 infection to help benchmark study quality, improve cross-institutional comparison of data, and assess therapeutic efficacy so that potential drugs and vaccines for SAR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd551a0a699d764b2344605c599bfb34
https://doi.org/10.1177/03009858221095794
https://doi.org/10.1177/03009858221095794
Autor:
Samuel J. Vidal, Elena Bekerman, Derek Hansen, Bing Lu, Kelly Wang, Judy Mwangi, William Rowe, Federico Campigotto, Jim Zheng, Darryl Kato, Abishek Chandrashekar, Julia Barrett, Shivani Patel, Huahua Wan, Tochi Anioke, Noe B. Mercado, Joseph P. Nkolola, Melissa J. Ferguson, William J. Rinaldi, Christian Callebaut, Wade Blair, Tomas Cihlar, Romas Geleziunas, Stephen R. Yant, Dan H. Barouch
Publikováno v:
Nature
Because no currently available vaccine can prevent HIV infection, pre-exposure prophylaxis (PrEP) with antiretrovirals (ARVs) is an important tool for combating the HIV pandemic1,2. Long-acting ARVs promise to build on the success of current PrEP str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18528a97089342386940b1681f96dfdc
http://europepmc.org/articles/PMC8753592
http://europepmc.org/articles/PMC8753592
Autor:
Anthony L. Cook, Xuan He, Jake Yalley-Ogunro, Ralph S. Baric, Stefan O. Mueller, David R. Martinez, Jinyan Liu, Andrew C. Cole, Tori Giffin, Hanne Leth Andersen, Daniel Valentin, Benjamin Petsch, Katherine McMahan, Dan H. Barouch, Noe B. Mercado, Shivani A. Patel, Laurent Pessaint, Renita Brown, Jeanne Muench, Julia Barrett, David L. Hope, Adrianus C. M. Boon, Mark G. Lewis, Abishek Chandrashekar, Owen Sanborn, Makda S. Gebre, Zack Flinchbaugh, Xiaowen Liu, Susanne Rauch, Elyse Teow, Daniel Sellers, Amanda J. Martinot, Nicole Roth, Jingyou Yu
Publikováno v:
Nature
The CVnCoV (CureVac) mRNA vaccine for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) was recently evaluated in a phase 2b/3 efficacy trial in humans1. CV2CoV is a second-generation mRNA vaccine containing non-modified nucleosides but wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::728b9b23d77e0d900d6d664324e1d649
http://europepmc.org/articles/PMC8770133
http://europepmc.org/articles/PMC8770133