Native Cryo-Correlative Light and Synchrotron X‑ray Fluorescence Imaging of Proteins and Essential Metals in Subcellular Neuronal Compartments

Autor: Richard Ortega, Mónica Fernández-Monreal, Noémie Pied, Stéphane Roudeau, Peter Cloetens, Asuncion Carmona

Publikováno v: Chemical & Biomedical Imaging, Vol 2, Iss 11, Pp 744-754 (2024)

Externí odkaz: https://doaj.org/article/576ff9dc9bfc4a0e90192ad7b32c6b07

TBK1 is part of a galectin 8 dependent membrane damage recognition complex and drives autophagy upon Adenovirus endosomal escape.

Autor: Noémie Pied, Coralie F Daussy, Zoé Denis, Jessica Ragues, Muriel Faure, Richard Iggo, Mario P Tschan, Benoit Roger, Fabienne Rayne, Harald Wodrich

Publikováno v: PLoS Pathogens, Vol 18, Iss 7, p e1010736 (2022)

Intracellular pathogens cause membrane distortion and damage as they enter host cells. Cells perceive these membrane alterations as danger signals and respond by activating autophagy. This response has primarily been studied during bacterial invasion

Externí odkaz: https://doaj.org/article/78bc06bead7543b6956fd66c5d713739

Bronchial epithelia from adults and children: SARS-CoV-2 spread via syncytia formation and type III interferon infectivity restriction

Autor: Guillaume Beucher, Marie-Lise Blondot, Alexis Celle, Noémie Pied, Patricia Recordon-Pinson, Pauline Esteves, Muriel Faure, Mathieu Métifiot, Sabrina Lacomme, Denis Dacheux, Derrick R. Robinson, Gernot Längst, Fabien Beaufils, Marie-Edith Lafon, Patrick Berger, Marc Landry, Denis Malvy, Thomas Trian, Marie-Line Andreola, Harald Wodrich

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (28), ⟨10.1073/pnas.2202370119⟩

International audience; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections initiate in the bronchi of the upper respiratory tract and are able to disseminate to the lower respiratory tract, where infections can cause an acute res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e0d2eef99823f2ac361a27dc432c3a3
https://doi.org/10.1073/pnas.2202370119

Understanding Post Entry Sorting of Adenovirus Capsids; A Chance to Change Vaccine Vector Properties

Autor: Noémie Pied, Coralie F. Daussy, Harald Wodrich

Publikováno v: Viruses, Vol 13, Iss 1221, p 1221 (2021)
Viruses

Adenovirus vector-based genetic vaccines have emerged as a powerful strategy against the SARS-CoV-2 health crisis. This success is not unexpected because adenoviruses combine many desirable features of a genetic vaccine. They are highly immunogenic a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b1e7b803e0f906cb0cec2d3017294e5
https://www.mdpi.com/1999-4915/13/7/1221