Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Nodi Dehvari"'
Autor:
Emanuela Talamonti, Jelena Davegardh, Anastasia Kalinovich, Sten M.M. van Beek, Nodi Dehvari, Carina Halleskog, Hamza M. Bokhari, Dana S. Hutchinson, Seungmin Ham, Laura J. Humphrys, Nicola C. Dijon, Aikaterini Motso, Anna Sandstrom, Evelyn Zacharewicz, Ilga Mutule, Edgars Suna, Jana Spura, Karolina Ditrychova, Leigh A. Stoddart, Nicholas D. Holliday, Shane C. Wright, Volker M. Lauschke, Soren Nielsen, Camilla Scheele, Elizabeth Cheesman, Joris Hoeks, Peter Molenaar, Roger J. Summers, Benjamin Pelcman, Gopala K. Yakala, Tore Bengtsson
Publikováno v:
Molecular Metabolism, Vol 85, Iss , Pp 101931- (2024)
Objective: Simultaneous activation of β2- and β3-adrenoceptors (ARs) improves whole-body metabolism via beneficial effects in skeletal muscle and brown adipose tissue (BAT). Nevertheless, high-efficacy agonists simultaneously targeting these recept
Externí odkaz:
https://doaj.org/article/3d4a3a5490234ea7a397025d54414624
Autor:
Jessica M. Olsen, Robert I. Csikasz, Nodi Dehvari, Li Lu, Anna Sandström, Anette I. Öberg, Jan Nedergaard, Sharon Stone-Elander, Tore Bengtsson
Publikováno v:
Molecular Metabolism, Vol 6, Iss 6, Pp 611-619 (2017)
Objective: Today, the presence and activity of brown adipose tissue (BAT) in adult humans is generally equated with the induced accumulation of [2-18F]2-fluoro-2-deoxy-d-glucose ([18F]FDG) in adipose tissues, as investigated by positron emission tomo
Externí odkaz:
https://doaj.org/article/a8709001969046e0a106db48671aca25
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22304 (2011)
The β-adrenoceptors (β-ARs) control many cellular processes. Here, we show that β-ARs inhibit calcium depletion-induced cell contractility and subsequent cell detachment of L6 skeletal muscle cells. The mechanism underlying the cell detachment inh
Externí odkaz:
https://doaj.org/article/9e387313b2c041f6bbec5c320458da75
Autor:
Anette I Öberg, Kamal Yassin, Robert I Csikasz, Nodi Dehvari, Irina G Shabalina, Dana S Hutchinson, Mona Wilcke, Claes-Göran Östenson, Tore Bengtsson
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22510 (2011)
BACKGROUND: There is considerable interest in identifying compounds that can improve glucose homeostasis. Skeletal muscle, due to its large mass, is the principal organ for glucose disposal in the body and we have investigated here if shikonin, a nap
Externí odkaz:
https://doaj.org/article/dc1c4b6a7ed544d58832219fdd75fce4
Autor:
Claes-Göran Östenson, Joris Hoeks, Tore Bengtsson, Anastasia V. Kalinovich, Carina Halleskog, Nodi Dehvari, Jessica M. Olsen, Alice Åslund, Gert Schaart, Elisabete Forsberg, Anna L. Sandström, Evelyn Zacharewicz, Sten M M van Beek, Roger Berlin, Mia Rinde
Publikováno v:
Diabetologia
Diabetologia, 63(8), 1603-1615. Springer, Cham
Diabetologia, 63(8), 1603-1615. Springer, Cham
Aims/hypothesis Chronic stimulation of β2-adrenoceptors, opposite to acute treatment, was reported to reduce blood glucose levels, as well as to improve glucose and insulin tolerance in rodent models of diabetes by essentially unknown mechanisms. We
Autor:
Michelle L. Halls, Anna L. Sandström, Dana S. Hutchinson, Masaaki Sato, Nodi Dehvari, Jon Merlin, Robert I. Csikasz, Roger J. Summers, Anette I. Öberg, Saori Mukaida, Jessica M. Olsen, Tore Bengtsson, Bronwyn A Evans, Martina Kocan
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 316:R666-R677
The type 2 diabetes epidemic makes it important to find insulin-independent ways to improve glucose homeostasis. This study examines the mechanisms activated by a dual β2-/β3-adrenoceptor agonist, BRL37344, to increase glucose uptake in skeletal mu
Autor:
Masaaki Sato, Lynda Whiting, Dana S. Hutchinson, Seungmin Ham, Denise Wootten, Tore Bengtsson, Anastasia V. Kalinovich, Ling Yeong Chia, Saori Mukaida, Bronwyn A Evans, Nodi Dehvari, Jon Merlin, Huong T. M. Nguyen, Muhammad Hamza Bokhari, Roger J. Summers, Jie Gao
Publikováno v:
Pharmacology Research & Perspectives. 8
The β3 -adrenoceptor agonist mirabegron is approved for use for overactive bladder and has been purported to be useful in the treatment of obesity-related metabolic diseases in humans, including those involving disturbances of glucose homeostasis. W
Autor:
Nodi, Dehvari, Masaaki, Sato, Muhammad Hamza, Bokhari, Anastasia, Kalinovich, Seungmin, Ham, Jie, Gao, Huong T M, Nguyen, Lynda, Whiting, Saori, Mukaida, Jon, Merlin, Ling Yeong, Chia, Denise, Wootten, Roger J, Summers, Bronwyn A, Evans, Tore, Bengtsson, Dana S, Hutchinson
Publikováno v:
Pharmacology Research & Perspectives
The β3‐adrenoceptor agonist mirabegron is approved for use for overactive bladder and has been purported to be useful in the treatment of obesity‐related metabolic diseases in humans, including those involving disturbances of glucose homeostasis
Publikováno v:
British Journal of Pharmacology. 175:4072-4082
The β3 -adrenoceptor was initially an attractive target for several pharmaceutical companies due to its high expression in rodent adipose tissue, where its activation resulted in decreased adiposity and improved metabolic outputs (such as glucose ha
Autor:
Dana S. Hutchinson, Saori Mukaida, Masaaki Sato, Lynda Whiting, Roger J. Summers, Tore Bengtsson, Jon Merlin, Jie Gao, Nodi Dehvari, Bronwyn A Evans
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. :PO1-5