Protocol for a pilot and feasibility randomized-controlled trial of four weeks of oral γ-aminobutyric acid (GABA) intake and its effect on pain and sleep in middle-to-older aged adults.

Autor: Montesino-Goicolea S; Pain Research & Intervention Center of Excellence, University of Florida, Gainesville, FL, USA.; Department of Community Dentistry & Behavioral Science, College of Dentistry, University of Florida, Gainesville, FL, USA.; Institute on Aging, University of Florida, Gainesville, FL, USA., Nin O; Department of Anesthesiology, College of Medicine, University of Florida, Gainesville, FL, USA., Gonzalez BM; Pain Research & Intervention Center of Excellence, University of Florida, Gainesville, FL, USA.; Department of Community Dentistry & Behavioral Science, College of Dentistry, University of Florida, Gainesville, FL, USA., Sawczuk NJ; Pain Research & Intervention Center of Excellence, University of Florida, Gainesville, FL, USA.; Department of Community Dentistry & Behavioral Science, College of Dentistry, University of Florida, Gainesville, FL, USA., Nodarse CL; Pain Research & Intervention Center of Excellence, University of Florida, Gainesville, FL, USA.; Department of Community Dentistry & Behavioral Science, College of Dentistry, University of Florida, Gainesville, FL, USA., Valdes-Hernandez PA; Pain Research & Intervention Center of Excellence, University of Florida, Gainesville, FL, USA.; Department of Community Dentistry & Behavioral Science, College of Dentistry, University of Florida, Gainesville, FL, USA., Jackson E; Pain Research & Intervention Center of Excellence, University of Florida, Gainesville, FL, USA.; Department of Community Dentistry & Behavioral Science, College of Dentistry, University of Florida, Gainesville, FL, USA., Huo Z; Department of Biostatistics, College of Public Health & Health Professions and College of Medicine, University of Florida, Gainesville, FL, USA., Somerville JET; Pain Research & Intervention Center of Excellence, University of Florida, Gainesville, FL, USA.; Department of Community Dentistry & Behavioral Science, College of Dentistry, University of Florida, Gainesville, FL, USA., Porges EC; Center for Cognitive Aging & Memory, McKnight Brain Foundation, University of Florida, Gainesville, FL, USA.; Department of Clinical and Health Psychology College of Public Health and Health Professions, University of Florida, Gainesville, FL, USA., Smith C; Department of Anesthesiology, College of Medicine, University of Florida, Gainesville, FL, USA., Fillingim RB; Pain Research & Intervention Center of Excellence, University of Florida, Gainesville, FL, USA.; Department of Community Dentistry & Behavioral Science, College of Dentistry, University of Florida, Gainesville, FL, USA.; Institute on Aging, University of Florida, Gainesville, FL, USA., Cruz-Almeida Y; Pain Research & Intervention Center of Excellence, University of Florida, Gainesville, FL, USA.; Center for Cognitive Aging & Memory, McKnight Brain Foundation, University of Florida, Gainesville, FL, USA.; Department of Community Dentistry & Behavioral Science, College of Dentistry, University of Florida, Gainesville, FL, USA.; Institute on Aging, University of Florida, Gainesville, FL, USA.

Publikováno v: Contemporary clinical trials communications [Contemp Clin Trials Commun] 2023 Jan 20; Vol. 32, pp. 101066. Date of Electronic Publication: 2023 Jan 20 (Print Publication: 2023).

Clinical vitamin D levels are associated with insular volume and inferior temporal gyrus white matter surface area in community-dwelling individuals with knee pain.

Autor: Strath LJ; Pain Research and Intervention Center of Excellence, University of Florida, Gainesville, FL, United States.; Department of Community Dentistry and Behavioral Science, University of Florida, Gainesville, FL, United States., Hernandez PV; Pain Research and Intervention Center of Excellence, University of Florida, Gainesville, FL, United States.; Department of Community Dentistry and Behavioral Science, University of Florida, Gainesville, FL, United States., Nodarse CL; Pain Research and Intervention Center of Excellence, University of Florida, Gainesville, FL, United States.; Department of Community Dentistry and Behavioral Science, University of Florida, Gainesville, FL, United States., Johnson AJ; Pain Research and Intervention Center of Excellence, University of Florida, Gainesville, FL, United States.; Department of Community Dentistry and Behavioral Science, University of Florida, Gainesville, FL, United States., Edberg JD; School of Medicine, The University of Alabama at Birmingham, Birmingham, AL, United States., Fillingim RB; Pain Research and Intervention Center of Excellence, University of Florida, Gainesville, FL, United States.; Department of Community Dentistry and Behavioral Science, University of Florida, Gainesville, FL, United States., Cruz-Almeida Y; Pain Research and Intervention Center of Excellence, University of Florida, Gainesville, FL, United States.; Department of Community Dentistry and Behavioral Science, University of Florida, Gainesville, FL, United States.

Publikováno v: Frontiers in neuroscience [Front Neurosci] 2022 Aug 31; Vol. 16, pp. 882322. Date of Electronic Publication: 2022 Aug 31 (Print Publication: 2022).

Polygenic risk for epigenetic aging and adverse life experiences interact to predict growth in adolescent depression in a racially/ethnically diverse sample.

Autor: Elam, Kit K., Su, Jinni, Qin, Weisiyu Abraham, Lemery-Chalfant, Kathryn

Publikováno v: Frontiers in Psychiatry; 2025, p1-13, 13p

Bewegungsmangel : Dekonditionierung, Krankheit, Schmerzen, Altern

Autor: Wolfgang Laube

Bewegungsmangel gilt als wichtiger Risiko- und Realisationsfaktor für die Entwicklung von de facto fast allen chronischen Erkrankungen, wie z.B. Adipositas, Diabetes, Arteriosklerose, Arthrose oder auch neurodegenerativen Veränderungen. Zur Hauptur