Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nodar Surguladze"'
Autor:
Xiaoli Liu, Jonas M. Sheehan, Becky Slagle-Webb, A. B. Madhankumar, James R. Connor, Nodar Surguladze
Publikováno v:
Cancer Research. 71:2240-2249
Approximately half of all gliomas are resistant to chemotherapy, and new therapeutic strategies are urgently needed to treat this cancer. We hypothesized that disrupting iron homeostasis in glioma cells could block tumor growth, based on an acute req
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e839f70a0ee3f9910afb22e17e58e55
https://doi.org/10.1158/0008-5472.can-10-1375
https://doi.org/10.1158/0008-5472.can-10-1375
Autor:
Elizabeth B. Neely, Bozho Todorich, James R. Connor, James O. Olopade, Nodar Surguladze, Xuesheng Zhang
Publikováno v:
Neurotoxicity Research. 19:361-373
The second post-natal week in rat is the period of the most intense oligodendrocyte development and myelination. This period coincides with peak iron import by oligodendrocytes. During that time oligodendrocyte progenitors (OPCs) are sensitive to age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05b355998b0bad76c56f0dc316e36d22
https://doi.org/10.1007/s12640-010-9167-1
https://doi.org/10.1007/s12640-010-9167-1
Publikováno v:
Glia. 54:795-804
Previously, we have reported that there is a spatiotemporal relationship between iron accumulation in microglia and oligodendrocytes during normal development and in remyelination following injury. This in vivo observation has prompted us to develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c44aae9058a665cfc25f021940d4b5d9
https://doi.org/10.1002/glia.20416
https://doi.org/10.1002/glia.20416
Publikováno v:
Journal of Cell Science. 118:4365-4373
Interaction between iron regulatory proteins and iron responsive elements on certain mRNAs is at the core of regulation of intracellular iron homeostasis. Previous results suggested that in cultured cells iron regulatory proteins (IRPs) exist in cyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd62e57588966b0de8c3150f8b81354a
https://doi.org/10.1242/jcs.02570
https://doi.org/10.1242/jcs.02570
Publikováno v:
Biochemical Journal. 388:731-740
Ferritin, normally considered a cytoplasmic iron-storage protein, is also found in cell nuclei. It is an established fact that H-ferritin is the major form of nuclear ferritin, but little is known about the roles of ferritin in nuclei or about the me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::974f3201d36260d0b55982534699503b
https://doi.org/10.1042/bj20041853
https://doi.org/10.1042/bj20041853
Autor:
Michael P. Haaf, James R. Connor, Henry Schieremberg, Xuesheng Zhang, Nodar Surguladze, Erin Grosstephan, Bozho Todorich
Publikováno v:
Glia. 52:199-208
Inflammatory processes play a key role in the pathogenesis of a number of common neurodegenerative disorders such as Alzheimer's disease (AD), Parkinson's disease (PD), and multiple sclerosis (MS). Abnormal iron accumulation is frequently noted in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1abd1737c40380231e6c6f18eb110387
https://doi.org/10.1002/glia.20235
https://doi.org/10.1002/glia.20235
Autor:
Becky Slagle-Webb, Xiaoli Liu, A.B. Madhankumar, James R. Connor, Jonas M. Sheehan, Nodar Surguladze
Publikováno v:
Cancer Research. 70:5529-5529
Cancer cells have a robust appetite for iron to support their rapid growth and high metabolic rates. The high levels of iron uptake require a mechanism to limit iron induced oxidative damage. This function is the responsibility of ferritin; an intrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03fe85440caec08382e3821b60f30930
https://doi.org/10.1158/1538-7445.am10-5529
https://doi.org/10.1158/1538-7445.am10-5529
Autor:
Xuesheng Zhang, Michael Haaf, Bozho Todorich, Erin Grosstephan, Henry Schieremberg, Nodar Surguladze, James R. Connor
Publikováno v:
Glia; Nov2005, Vol. 52 Issue 3, p199-208, 0p