Zobrazeno 1 - 10
of 1 426
pro vyhledávání: '"Nod-like receptors"'
Publikováno v:
Pharmacological Research, Vol 208, Iss , Pp 107411- (2024)
Despite considerable improvements in understanding the biology of glioblastoma (GB), it still remains the most lethal type of brain tumor in adults. The role of innate immune cells in the development of GB was recently described. In particular, the t
Externí odkaz:
https://doaj.org/article/74451c2136384b60bf5269783fa2a188
Autor:
O. P. Lebedeva, V. M. Ivannikova, I. O. Zhukova, O. N. Kozarenko, O. B. Altukhova, S. P. Pakhomov, M. I. Churnosov
Publikováno v:
Акушерство, гинекология и репродукция, Vol 17, Iss 5, Pp 554-564 (2023)
Nucleotide-binding oligomerization domain-like receptors (NOD-like receptors) are cytosolic signaling receptors of innate immune cells recognizing ligands derived from bacteria, viruses, fungi and protozoa. They can initiate apoptosis and pro-inflamm
Externí odkaz:
https://doaj.org/article/d9cc7834f6eb474fad72e75dc3ba312c
Publikováno v:
Biomedical Journal, Vol 47, Iss 1, Pp 100655- (2024)
Nod-like receptors (NLRs) are innate immune receptors that play a key role in sensing components from pathogens and from damaged cells or organelles. NLRs form signaling complexes that can lead to activation of transcription factors or effector caspa
Externí odkaz:
https://doaj.org/article/53452d5c30f945b1983c24e7f5afbddf
Publikováno v:
Biomedical Journal, Vol 47, Iss 1, Pp 100635- (2024)
NLRX1 is a member of the of the Nod-like receptor (NLR) family, and it represents a unique pattern recognition molecule (PRM) as it localizes to the mitochondrial matrix in resting conditions. Over the past fifteen years, NLRX1 has been proposed to r
Externí odkaz:
https://doaj.org/article/7b83b3daae22408cb5c490b114c21e9a
Publikováno v:
Biomedical Journal, Vol 47, Iss 1, Pp 100637- (2024)
It has long been appreciated that cues from the innate immune system orchestrate downstream adaptive immune responses. Although previous work has focused on the roles of Toll-like receptors in this regard, relatively little is known about how Nod-lik
Externí odkaz:
https://doaj.org/article/a7d006034a1e456292fb5dc39c53310c
Publikováno v:
Pathogens, Vol 13, Iss 7, p 561 (2024)
Influenza virus possesses an RNA genome of single-stranded, negative-sensed, and segmented configuration. Influenza virus causes an acute respiratory disease, commonly known as the “flu” in humans. In some individuals, flu can lead to pneumonia a
Externí odkaz:
https://doaj.org/article/77ff552fed964a83ae89c691df71f7fe
Autor:
Nagai-Singer, Margaret Ann
The innate immune system houses cellular signaling proteins called pattern recognition receptors (PRRs) that are responsible for recognizing highly-conserved molecular patterns associated with pathogens or damage to elicit an immune response. However
Externí odkaz:
http://hdl.handle.net/10919/113834
Autor:
Vincenzo Giambra, Danilo Pagliari, Pierluigi Rio, Beatrice Totti, Chiara Di Nunzio, Annalisa Bosi, Cristina Giaroni, Antonio Gasbarrini, Giovanni Gambassi, Rossella Cianci
Publikováno v:
Cells, Vol 12, Iss 22, p 2654 (2023)
Inflammatory bowel diseases (IBDs) are characterized by a persistent low-grade inflammation that leads to an increased risk of colorectal cancer (CRC) development. Several factors are implicated in this pathogenetic pathway, such as innate and adapti
Externí odkaz:
https://doaj.org/article/4b53fa385d324343974360caf5482c4a
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Inflammasomes, composed of the nucleotide-binding oligomerization domain(NOD)-like receptors (NLRs), are immune-functional protein multimers that are closely linked to the host defense mechanism. When NLRs sense pathogen-associated molecular patterns
Externí odkaz:
https://doaj.org/article/19c90f9466bd4ba28b0f17dbd4370ec0
Autor:
Cássio Luiz Coutinho Almeida-da-Silva, Luiz Eduardo Baggio Savio, Robson Coutinho-Silva, David M. Ojcius
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The innate immune system in vertebrates and invertebrates relies on conserved receptors and ligands, and pathways that can rapidly initiate the host response against microbial infection and other sources of stress and danger. Research into the family
Externí odkaz:
https://doaj.org/article/e59bc8d15605420ca2a7adbf16ee34f4