Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Nobuyuki TOSHIKUNI"'
Autor:
Nobuyuki Toshikuni
Publikováno v:
Gut and Liver, Vol 11, Iss 3, Pp 335-348 (2017)
Chronic hepatitis C virus (HCV) infection may eventually lead to liver cirrhosis (LC), a condition associated with a high risk of liver failure and hepatocellular carcinoma. Although interferon (IFN)-based therapy has made substantial contributions t
Externí odkaz:
https://doaj.org/article/f84e0a7a886542c38b48689f69ceb210
Publikováno v:
Annals of Hepatology, Vol 15, Iss 3, Pp 314-325 (2016)
Bleeding from gastroesophageal varices (GEV) is a serious event in cirrhotic patients and can cause death. According to the explosion theory, progressive portal hypertension is the primary mechanism underlying variceal bleeding. There are two approac
Externí odkaz:
https://doaj.org/article/0127a2638c55480fa4f424a082959b92
Publikováno v:
Canadian Journal of Gastroenterology and Hepatology, Vol 29, Iss 8, Pp 427-430 (2015)
BACKGROUND: The relationship between endocan expression and outcome in patients with chronic liver disease is not fully understood.
Externí odkaz:
https://doaj.org/article/4c1f39fb3edb4df29410ed29fe967995
Autor:
Nobuyuki Toshikuni, Mutsumi Tsuchishima, Atsushi Fukumura, Tomiyasu Arisawa, Mikihiro Tsutsumi
Publikováno v:
Gastroenterology Research and Practice, Vol 2017 (2017)
Alcoholic steatohepatitis (ASH) and nonalcoholic steatohepatitis (NASH) are representative types of fatty liver disease (FLD) and have similar histologic features. In this study, we aimed to compare the associations of the two FLD types with hyperten
Externí odkaz:
https://doaj.org/article/0a189e815bd0442cb8340364a78bd72b
Autor:
Yasuhiro Matsue, Mikihiro Tsutsumi, Nobuhiko Hayashi, Takashi Saito, Mutsumi Tsuchishima, Nobuyuki Toshikuni, Tomiyasu Arisawa, Joseph George
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118744 (2015)
Osteopontin (OPN) is a matricellular protein that upregulates during pathogenesis of hepatic fibrosis. The present study was aimed to evaluate whether serum OPN could be used as a biomarker to assess the degree of hepatic fibrosis in patients with he
Externí odkaz:
https://doaj.org/article/b0afc9dbd22b4683814d8ef359114909
Autor:
Nobuhiko Hayashi, Joseph George, Masayoshi Takeuchi, Atsushi Fukumura, Nobuyuki Toshikuni, Tomiyasu Arisawa, Mikihiro Tsutsumi
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e70034 (2013)
Chronic ingestion of ethanol increases acetaldehyde and leads to the production of acetaldehyde-derived advanced glycation end-products (AA-AGE). We evaluated the toxicity of AA-AGE on hepatocytes and studied the role of AA-AGE in the pathogenesis of
Externí odkaz:
https://doaj.org/article/ba6218d6dfa84ee9a2a84096e78961aa
Autor:
Kaori KINOSHITA1, Nobuyuki TOSHIKUNI1 n.toshikuni@gmail.com, Takashi SAITO1, Nobuhiko HAYASHI1, Takahiro MINATO1, Yasuhiro MATSUE1, Yoshimichi UEDA2, Mutsumi TSUCHISHIMA1, Mikihiro TSUTSUMI1
Publikováno v:
Turkish Journal of Medical Sciences. 2019, Vol. 49 Issue 5, p1350-1357. 8p.
Publikováno v:
Cancer Research. 82:5925-5925
Background: The newly developed albumin-bilirubin (ALBI) score has been proved to be a simple and useful marker for predicting prognosis in patients with hepatocellular carcinoma (HCC). However, evidence is scarce regarding the use of ALBI score to p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e76198e72d9fde6722685e903e1a04af
https://doi.org/10.1158/1538-7445.am2022-5925
https://doi.org/10.1158/1538-7445.am2022-5925
Autor:
Mikihiro Tsutsumi, Nobuyuki Toshikuni, Yasuhiro Matsue, Nobuhiko Hayashi, Kazuaki Ozaki, Mutsumi Tsuchishima, Kaho Yamada
Publikováno v:
Radiology and Oncology
Radiology and Oncology, Vol 51, Iss 3, Pp 263-269 (2017)
Radiology and Oncology, Vol 51, Iss 3, Pp 263-269 (2017)
BackgroundDuring ultrasound-guided radiofrequency ablation (RFA) of hepatocellular carcinoma (HCC), high echoic areas due to RFA-induced microbubbles can help calculate the extent of ablation. However, these areas also decrease visualization of targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2099e53068183039bba7e02a48fa1b9
https://doi.org/10.1515/raon-2017-0028
https://doi.org/10.1515/raon-2017-0028
Autor:
Yasuhiro Matsue, Kaori Kinoshita, Takashi Saito, Mutsumi Tsuchishima, Yoshimichi Ueda, Takahiro Minato, Nobuyuki Toshikuni, Mikihiro Tsutsumi, Nobuhiko Hayashi
Publikováno v:
Turkish Journal of Medical Sciences
Volume: 49, Issue: 5 1350-1357
Volume: 49, Issue: 5 1350-1357
Background/aim To elucidate how the combination of fatty liver and increased serum gamma-glutamyl transpeptidase (GGT) levels influences atherosclerotic plaque development in apparently healthy people. Materials and methods The study population inclu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e1a4fdb500cdb5b7c3571a9ba8b0c95
https://pubmed.ncbi.nlm.nih.gov/31648507
https://pubmed.ncbi.nlm.nih.gov/31648507