Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Nobuyuki Susa"'
Autor:
Hiroyuki Sugiyama, Takashige Kashimoto, Shunji Ueno, Hayato Ehara, Toshio Kodama, Tetsuya Iida, Nobuyuki Susa
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26018 (2011)
Vibrio vulnificus secretes a hemolysin/cytolysin (VVH) that induces cytolysis in target cells. A detergent resistant membrane domain (DRM) fraction of the cells after sucrose gradient centrifugation includes cholesterol-rich membrane microdomains whi
Externí odkaz:
https://doaj.org/article/838e61826c2a4e84ab4e814195da4433
Publikováno v:
Journal of Veterinary Medical Science. 75:649-652
Vibrio vulnificus secrets a pore-forming toxin called Vibrio vulnificus hemolysin (VVH). In this study, we showed that methyl-beta-cyclodextrin (MβCD), an oligosaccharide, decreased binding of VVH to Chinese hamster ovary (CHO) cells, resulting in i
Autor:
Shunji Ueno, Kyosuke Temma, Masaaki Ishikawa, Kenji Mizuta, Tadahiro Kawagoe, Takashige Kashimoto, Nobuyuki Susa, Masaaki Nishimura, Shino Homma-Takeda
Publikováno v:
Toxicological Sciences. 120:322-330
To clarify the relationship between DNA damage and free radical generation caused by smoking in vivo, DNA damage was investigated in the mouse lung by single-cell gel electrophoresis assay after exposure to cigarette smoke (CS) or gas phase cigarette
Autor:
Maiko Toya, Nobuyuki Susa, Yu F. Sasaki, Yoshikazu Nishimura, Shunji Ueno, Shino Takeda-Homma, Masayasu Sugiyama, Hoshiko Natsume, Nobuhiko Ito, Takashige Kashimoto
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 634:135-145
The comet assay was performed to elucidate the linearity of calibration curves and detection limits for DNA damage in multiple organs of whole body X-irradiated mice, and rates of reduction in DNA damage by DNA repair during the irradiation period we
Autor:
Hiroyuki Sugiyama, Takashige Kashimoto, Nobuyuki Susa, Chiemi Iwasaki, Masashi Okamura, Kazuki Yoshioka, Masanori Gojo, Yuji Yamamoto, Shunji Ueno
Publikováno v:
FEMS Microbiology Letters. 362
Vibrio vulnificus causes rapid disseminating septicemia by oral infection in infected individuals who have an underlying disease, especially chronic liver diseases. Although the elucidation of specific risk factors for V. vulnificus infection in pati
Autor:
Kohshin Wada, Nobuhiko Ito, Masayasu Sugiyama, Takashige Kashimoto, Shino Takeda-Homma, Yoshikazu Nishimura, Shunji Ueno, Nobuyuki Susa
Publikováno v:
Free Radical Research. 40(9):944-951
Appropriate experimental conditions for the estimation of hydroxyl radical generation by salicylate hydroxylation were determined for multiple organs of X-irradiated mice in vivo. The in vitro experiments showed that there were significant correlatio
Autor:
Kenji Yoshida, Nobuyuki Susa, Miyuki Hanajima, Hisae Hayashi, Takashige Kashimoto, Shunji Ueno, Ken-ichiro Mutoh, Kazuki Yoshioka
Publikováno v:
Journal of Medical Microbiology. 54:15-22
Vibrio vulnificus causes severe sepsis in humans. There are several reports about the relationship between host immunity and bacterial growth in V. vulnificus infection. However, the effect on leukocytes of V. vulnificus infection in vivo has not bee
Publikováno v:
Toxicological Sciences. 54:104-109
According to published information, the lung is the only clear target organ for tumors when mice are exposed to cigarette smoke. Liver, skin, and upper digestive tract are target organs when orally or dermally exposed to cigarette smoke condensate, b
Autor:
Yu F. Sasaki, Kaoru Sekihashi, Noriko Kawamura, Naonori Matsusaka, Shuji Tsuda, Nobuyuki Susa, Hiroo Madarame, Kumiko Ishida, Shunji Ueno
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 465:11-26
The genotoxicity of 24 azo compounds selected from IARC (International Agency for Research on Cancer) groups 2A, 2B, and 3 were determined by the comet (alkaline single cell gel electrophoresis, SCG) assay in eight mouse organs. We treated groups of
Publikováno v:
Inorganica Chimica Acta. 263:189-194
Vanadate and chromate reduction in the presence of biocomponents like saccharides and L-ascorbic acid is demonstrated to generate V(IV) and Cr(III) species, respectively. The incipiently formed V(IV) and Cr(III) species are demonstrated to cause sing