Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Nobuyuki Sasakawa"'
Autor:
Natsumi Ikegawa, Ayari Kozuka, Nozomi Morita, Minetaka Murakami, Nobuyuki Sasakawa, Takako Niikura
Publikováno v:
Biochimica et biophysica acta. General subjects. 1866(10)
Humanin (HN) is an endogenous 24-residue peptide that was first identified as a protective factor against neuronal death in Alzheimer's disease (AD). We previously demonstrated that the highly potent HN derivative HNG (HN with substitution of Gly for
Autor:
Hideshi Ihara, Tomoaki Ida, Shingo Kasamatsu, Hiroyasu Tsutsuki, Kohei Kunieda, Takaaki Akaike, Nobuyuki Sasakawa, Tomohiro Sawa
Publikováno v:
Biochemical and biophysical research communications. 526(1)
Nitric oxide (NO)-mediated production of cyclic guanosine 3',5'-monophosphate (cGMP) is a crucial signaling pathway that controls a wide array of neuronal functions, including exocytotic neurotransmitter release. A novel nitrated derivative of cGMP,
Autor:
Osamu Sato, Mitsuo Ikebe, Yoshiaki Komiya, Michitoshi Watanabe, Tatsuo Ushiki, Ryoki Ishikawa, Kazushige Nomura, Kohei Hosaka, Hisaaki Taniguchi, Konosuke Kumakura, Emiko Yamauchi, Michihiro Igarashi, Nobuyuki Sasakawa, Akihiro Ohyama
Publikováno v:
Molecular Biology of the Cell. 16:4519-4530
Myosin-Va is an actin-based processive motor that conveys intracellular cargoes. Synaptic vesicles are one of the most important cargoes for myosin-Va, but the role of mammalian myosin-Va in secretion is less clear than for its yeast homologue, Myo2p
Publikováno v:
Cellular and Molecular Neurobiology. 25:777-787
Exocytotic events from rat pheochromocytoma (PC12) cells were characterized by amperometric analysis. For single-cell amperometric recordings, PC12h cells cultured onto poly-L-lysine corted glass-base dish were incubated with 1 mM dopamine (DA) for 6
Publikováno v:
Biochemical Pharmacology. 50:137-146
Autor:
Hideyuki Arimitsu, Mitsunori Hayashi, Masafumi Mukamoto, Nobuyuki Sasakawa, Yuto Shibata, Keiji Nakamura, Kentaro Tsukamoto, Tomoko Kohda, Shunji Kozaki
Clostridium botulinum types C and D cause animal botulism by the production of serotype-specific or mosaic botulinum neurotoxin (BoNT). The D/C mosaic BoNT (BoNT/DC), which is produced by the isolate from bovine botulism in Japan, exhibits the highes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae57431647a2d514a0f9126e0f1f8979
https://europepmc.org/articles/PMC3434576/
https://europepmc.org/articles/PMC3434576/
Publikováno v:
Molecular and Cellular Endocrinology. 100:115-119
Autor:
Masahiko Watabe, Koji Aoyama, Nobuyuki Sasakawa, Mami Ishizaka, Toshio Nakaki, Nobuko Matsumura, Kazue Kikuchi-Utsumi
Publikováno v:
Neurotoxicity research. 24(2)
Methamphetamine (METH) is a psychostimulant that damages nigrostriatal dopaminergic terminals, primarily by enhancing dopamine and glutamate release. α₁-adrenergic receptor (AR) subtype involved in METH-induced neurotoxicity in rats was investigat
Autor:
Hiroyuki Kabayama, Konosuke Kumakura, Nobuyuki Sasakawa, Mitsunori Fukuda, Katsuhiko Mikoshiba, Mica Ohara-Imaizumi
Publikováno v:
Neuropharmacology. 60(7-8)
Synaptotagmins (Syts) serve as a Ca2+ sensor in the release of neurotransmitters and hormones. Inositol polyphosphates (InsPPs) such as Inositol 1,3,4,5,6-pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6) bind to Ca2+-binding C2B domain
Publikováno v:
Journal of Neurochemistry. 58:2116-2123
When [3H]inositol-prelabelled N1E-115 cells were stimulated with carbamylcholine (CCh) (100 microM), high K+ (60 mM), and prostaglandin E1 (PGE1) (10 microM), a transient increase in [3H]inositol pentakisphosphate (InsP5) accumulation was observed. T