Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nobuyuki Izumisawa"'
Autor:
Naoki Kaneko, Kentaro Yamanaka, Takahito Nakahara, Hiroshi Koutoku, Nobuyuki Izumisawa, Kenji Nakano, Aya Kita, Masao Sasamata, Masamichi Mori, Mari Nakata
Publikováno v:
Leukemia Research. 35:787-792
YM155, a novel small-molecule that down-regulates survivin, exhibits broad, potent antitumor activity against a range of human tumors. We evaluated the activity of YM155 in aggressive non-Hodgkin lymphoma. In a number of diffuse large B-cell lymphoma
Autor:
Ayano Takeuchi, Satoru Kajikawa, Kenji Nakano, Mihoko Ono, Yoshiko Nishimuta, Nobuyuki Izumisawa, Katsuhisa Shiraki, Kyoko Ito
Publikováno v:
Journal of Toxicologic Pathology. 20:161-166
A large, well-demarcated solitary mass appeared in the chest of an intact female Sprague-Dawley rat. The tumor cells were generally small and round, with scant eosinophilic cytoplasm, and arranged in an alveolar pattern. In some areas, the tumor cell
Publikováno v:
Experimental Neurology. 134:199-204
The neuroprotective properties of glutamate receptor antagonists arise from their ability to antagonize the excitotoxic actions of endogenous excitatory amino acids. However, J. W. Olney et al. (1989, Science 224: 1360-1362) have reported that MK-801
Autor:
Takashi Nakamura, Noboru Machida, Nobuyuki Izumisawa, Keiji Kiryu, Tetsuya Kitayama, Takashi Suzuki
Publikováno v:
Heart and Vessels. 9:96-103
Postmortem coronary angiography was performed in 20 beagles and 15 mongrels, and the origin and distribution of the sinus node arteries (SNAs) were subsequently investigated using soft X-ray radiography, the tissue clearing method, and histological e
Publikováno v:
Journal of Comparative Pathology. 108:383-392
From September to December 1991, a large number of free-ranging raccoon dogs (Nyctereutes procyonoides) died from a highly contagious disease in the vicinity of Tokyo. Eighteen seriously ill or dead animals were submitted for necropsy. The pathologic
Publikováno v:
Journal of Comparative Pathology. 107:439-443
A free-living masked palm civet (Paguma larvata) died after exhibiting signs of canine distemper (CD). The microscopic lesions consisted of cytoplasmic and intranuclear eosinophilic inclusion bodies, bronchointerstitial pneumonia, non-purulent enceph
Autor:
Kyoko Ito, Aisuke Nii, Katsuhiko Ishida, Nobuyuki Izumisawa, Takanori Hanada, Kou Narita, Hideaki Okamiya
Publikováno v:
Journal of Toxicologic Pathology. 13:189-191
Histologic and morphometric variations in the thyroid glands were investigated in twenty normal Cynomolgus monkeys. Heterogeneity in the pattern of colloid staining and the appearance of degenerating cells were frequently observed in the lumina of th
Autor:
Ayano Takeuchi, Yuuji Toyoda, Hajime Tabata, Nobuyuki Izumisawa, Kouji Watanabe, Takafumi Shirakawa
Publikováno v:
Experimental and Toxicologic Pathology. 61:288
Myocardial necrosis in cynomolgus monkey is one of the most difficult findings to get interpreted in the toxicity study. Here, we examined the role of hypokalemia, one of the possible causes to induce myocardial necrosis, using a diuretic hydrochloro