Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Nobuyuki Imai"'
Autor:
Ken Ohta, Mitsuru Adachi, Yuji Tohda, Tadashi Kamei, Motokazu Kato, J. Mark Fitzgerald, Masayuki Takanuma, Tadahiro Kakuno, Nobuyuki Imai, Yanping Wu, Magnus Aurivillius, Mitchell Goldman
Publikováno v:
Allergology International, Vol 67, Iss 2, Pp 266-272 (2018)
Background: In the Phase III CALIMA trial, benralizumab significantly reduced asthma exacerbations, increased lung function, and alleviated symptoms for patients with severe, uncontrolled eosinophilic asthma. The aim of this subgroup analysis was to
Externí odkaz:
https://doaj.org/article/ada1b0cb627641cb9cc7dec4059d16a2
Publikováno v:
SSRN Electronic Journal.
Publikováno v:
Tetrahedron. 127:133102
Publikováno v:
Tetrahedron Letters. 108:154130
Publikováno v:
Synthesis. 51:3683-3696
Acetaminophen is a popular antipyretic analgesic medicine that has weaker anti-inflammatory properties and lower incidence of side effects than nonsteroidal anti-inflammatory drugs (NSAIDs). However, acetaminophen causes hepatotoxicity due to the rea
Publikováno v:
Tetrahedron: Asymmetry. 28:1690-1699
Primary amidations of carboxylic acids 1 or 3 with NH4Cl in the presence of ClCO2Et and Et3N were developed to afford the corresponding primary amides in 22% to quantitative yields. Additionally, we have applied the amidation to the preparation of va
Publikováno v:
Bulletin of the Chemical Society of Japan. 90:689-696
The coupling reactions of 3-phenylpropanoic acid and N-carboxybenzyl α-amino acids with unprotected α-amino acids containing hydrophilic side chains such as aliphatic alcohol, aromatic alcohol, thi...
Publikováno v:
Tetrahedron: Asymmetry. 28:266-281
We have achieved a convenient enantioselective synthesis of memantine analogues containing a chiral cyclopropane skeleton as a sigma-1 receptor agonist in 19–40% overall chemical yields from the corresponding 2-arylbut-2-ene-1,4-diols with moderate
Publikováno v:
Tetrahedron: Asymmetry. 28:75-83
Dipeptides and amides were obtained in high yields from N-carbobenzyloxy α-amino acids and 3-phenylpropanoic acid with unprotected α-amino acids via the corresponding mixed carbonic carboxylic anhydrides using ethyl chloroformate and triethylamine
Autor:
Masashi Kawasaki, Taisuke Harada, Tetsuya Ezawa, Yuya Kawashima, Takuya Noguchi, Nobuyuki Imai, Masayuki Kirihara
Publikováno v:
Bulletin of the Chemical Society of Japan. 89:257-267
3-Substituted (Z)-4-hydroxybut-2-en-1-yl acylates were regioselectively obtained in 2–98% yields by acylations of the corresponding 2-substituted (Z)-but-2-ene-1,4-diols with 10 equiv of vinyl acyl...