Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Nobuyuki Hirai"'
Autor:
Daisuke Uno, Kazuhira Endo, Tomomi Yoshikawa, Nobuyuki Hirai, Eiji Kobayashi, Yosuke Nakanishi, Satoru Kondo, Tomokazu Yoshizaki
Publikováno v:
Thyroid Research, Vol 17, Iss 1, Pp 1-9 (2024)
Abstract Introduction Activation of the MAPK pathway by genetic mutations (such as BRAF and RET) initiates and accelerates the growth of papillary thyroid carcinoma (PTC). However, the correlation between genetic mutations and clinical features remai
Externí odkaz:
https://doaj.org/article/c9b65364cc504a00b68c1590d7d2b76e
Autor:
Kina Kase, Satoru Kondo, Naohiro Wakisaka, Hirotomo Dochi, Harue Mizokami, Eiji Kobayashi, Makoto Kano, Takeshi Komori, Nobuyuki Hirai, Takayoshi Ueno, Yosuke Nakanishi, Miyako Hatano, Kazuhira Endo, Makiko Moriyama-Kita, Hisashi Sugimoto, Tomokazu Yoshizaki
Publikováno v:
Microorganisms, Vol 9, Iss 3, p 603 (2021)
Nasopharyngeal carcinoma (NPC) is an Epstein–Barr virus (EBV)-associated malignancy. The principal oncogene of EBV, latent membrane protein 1 (LMP1), induces the expression of programmed death-ligand 1 (PD-L1), which is an immunosuppressive transme
Externí odkaz:
https://doaj.org/article/02b0d2ecb4084aceb6fff2cb0256588d
Autor:
Nobuyuki Hirai, Naohiro Wakisaka, Satoru Kondo, Mitsuharu Aga, Makiko Moriyama-Kita, Takayoshi Ueno, Yosuke Nakanishi, Kazuhira Endo, Hisashi Sugimoto, Shigeyuki Murono, Hiroshi Sato, Tomokazu Yoshizaki
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163609 (2016)
Epstein-Barr virus (EBV)-related micoRNAs (miRNAs), BamHI-A rightward transcripts (BART)-miRNAs, are released in a stable form from viable cells, which are abundant in patients with EBV-positive nasopharyngeal carcinoma (NPC). We estimated copy numbe
Externí odkaz:
https://doaj.org/article/84cd13735778412ba0d621bffdb6e144
Autor:
Hirotomo Dochi, Satoru Kondo, Takayuki Murata, Masaki Fukuyo, Asuka Nanbo, Kousho Wakae, Wen‐Ping Jiang, Toshihide Hamabe‐Horiike, Mariko Tanaka, Takumi Nishiuchi, Harue Mizokami, Makiko Moriyama‐Kita, Eiji Kobayashi, Nobuyuki Hirai, Takeshi Komori, Takayoshi Ueno, Yosuke Nakanishi, Miyako Hatano, Kazuhira Endo, Hisashi Sugimoto, Naohiro Wakisaka, Shin‐Hun Juang, Masamichi Muramatsu, Atsushi Kaneda, Tomokazu Yoshizaki
Publikováno v:
Cancer science. 113(8)
Several epidemiological studies have suggested that Epstein-Barr virus (EBV) lytic infection is essential for the development of nasopharyngeal carcinoma (NPC), as the elevation of antibody titers against EBV lytic proteins is a common feature of NPC
Autor:
Eiji Kobayashi, Satoru Kondo, Hirotomo Dochi, Makiko Moriyama-Kita, Nobuyuki Hirai, Takeshi Komori, Takayoshi Ueno, Yosuke Nakanishi, Miyako Hatano, Kazuhira Endo, Hisashi Sugimoto, Naohiro Wakisaka, Tomokazu Yoshizaki
Publikováno v:
Cancers. 14(12)
Nasopharyngeal carcinoma (NPC) is one of the Epstein–Barr virus (EBV)-associated malignancies. NPC is highly metastatic compared to other head and neck carcinomas, and evidence has shown that the metastatic features of NPC are involved in EBV infec
Autor:
Satoru Kondo, Yusuke Okuno, Takayuki Murata, Hirotomo Dochi, Naohiro Wakisaka, Harue Mizokami, Makiko Moriyama‐Kita, Eiji Kobayashi, Makoto Kano, Takeshi Komori, Nobuyuki Hirai, Takayoshi Ueno, Yosuke Nakanishi, Kazuhira Endo, Hisashi Sugimoto, Hiroshi Kimura, Tomokazu Yoshizaki
Publikováno v:
Cancer science. 113(7)
Nasopharyngeal carcinoma (NPC) is caused by infection with Epstein-Barr virus (EBV) and endemic in certain geographic regions. EBV lytic gene, BALF2, closely associates with viral reactivation and BALF2 gene variation, the H-H-H strain, causes NPC in
Autor:
Tomokazu Yoshizaki, Kazuhira Endo, Naohiro Wakisaka, Takeshi Komori, Satoru Kondo, Yosuke Nakanishi, Nobuyuki Hirai, Takayoshi Ueno
Publikováno v:
The Laryngoscope. 132
Autor:
Yosuke Nakanishi, Takeshi Komori, Naohiro Wakisaka, Takayoshi Ueno, Satoru Kondo, Kazuhira Endo, Nobuyuki Hirai, Tomokazu Yoshizaki
Publikováno v:
The Laryngoscope. 131
OBJECTIVES This study aimed to investigate whether pretreatment skeletal muscle mass index (SMI) is a predictor for the risk of aspiration pneumonia and to explore the relationship between low SMI and overall survival (OS) in patients with head and n
Autor:
Miyako Hatano, Nobuyuki Hirai, Eiji Kobayashi, Kazuhira Endo, Satoru Kondo, Tomokazu Yoshizaki, Naohiro Wakisaka, Hisashi Sugimoto, Yosuke Nakanishi, Mitsuharu Aga, Takayoshi Ueno, Kazuya Ishikawa
Publikováno v:
Cancer Science
Latent membrane protein 1 (LMP1) is a primary oncogene encoded by the Epstein‐Barr virus, and various portions of LMP1 are detected in nasopharyngeal carcinoma (NPC) tumor cells. LMP1 has been extensively studied since the discovery of its transfor
Autor:
Tomokazu Yoshizaki, Nobuyuki Hirai, Yosuke Nakanishi, Kazuhira Endo, Satoru Kondo, Naohiro Wakisaka, Akira Tsuji, Shigeyuki Murono, Mitsuharu Aga
Publikováno v:
Acta Oto-Laryngologica. 136(8):834-840
Conclusion: Reduced-RADPLAT for HPC achieved comparative survival and locoregional control rates with lower toxicities compared with concurrent chemoradiotherapies including original RADPLAT. S-1 adjuvant chemotherapy showed a survival benefit. Objec