Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Nobuyuki Fukuishi"'
Autor:
Masaaki Akagi, Nobuaki Matsui, Haruka Akae, Nana Hirashima, Nobuyuki Fukuishi, Yoshiyasu Fukuyama, Reiko Akagi
Publikováno v:
Journal of Pharmacological Sciences, Vol 127, Iss 2, Pp 155-163 (2015)
Developed regions, including Japan, have become “aged societies,” and the number of adults with senile dementias, such as Alzheimer's disease (AD), Parkinson's disease, and Huntington's disease, has also increased in such regions. Neurotrophins (
Externí odkaz:
https://doaj.org/article/6850f4a837384c6cae97aee8ca1055cf
Autor:
Hiroki Yoshioka, Haruki Usuda, Nobuhiko Miura, Nobuyuki Fukuishi, Tsunemasa Nonogaki, Satomi Onosaka
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176524 (2017)
The aim of this study was to determine whether calcium potentiates acute carbon tetrachloride (CCl4) -induced toxicity. Elevated calcium levels were induced in mice by pre-treatment with cholecalciferol (vitamin D3; V.D3), a compound that has previou
Externí odkaz:
https://doaj.org/article/bf0edca32bdb40bc8ba7980e84f22817
Autor:
Keiko Yamada, Hitomi Sato, Kazuma Sakamaki, Mayumi Kamada, Yasushi Okuno, Nobuyuki Fukuishi, Kazuyuki Furuta, Satoshi Tanaka
Publikováno v:
Cells, Vol 8, Iss 2, p 112 (2019)
Steroidal anti-inflammatory drugs are widely used for the treatment of chronic cutaneous inflammation, such as atopic dermatitis, although it remains unknown how they modulate cutaneous mast cell functions. We investigated the effects of prolonged tr
Externí odkaz:
https://doaj.org/article/a7c98187753f4c9c99fa058d841335bc
Publikováno v:
Heliyon, Vol 2, Iss 6 (2016)
The aim of this study is to investigate whether a Ca-deficient diet has an attenuating effect on carbon tetrachloride (CCl4)-induced hepatotoxicity. Four-week-old male ddY mice were fed a Ca-deficient diet for 4 weeks as a part of the experimental pr
Externí odkaz:
https://doaj.org/article/e73262b46e694f27a78e15b1eda02ad9
Publikováno v:
Journal of Pharmacological Sciences, Vol 99, Iss 4, Pp 400-407 (2005)
Patients with high serum immunoglobulin E levels were reported to be protected against sudden death during acute myocardial infarction. The protection mechanism might be attributed to the facilitation of histamine release from sensitized mast cells;
Externí odkaz:
https://doaj.org/article/9847039a1612439ba9ef9fcb51585a7f
Autor:
Nobuyuki Fukuishi, Yuusuke Igawa, Tomoyo Kunimi, Hirofumi Hamano, Masao Toyota, Hironobu Takahashi, Hiromichi Kenmoku, Yasuyuki Yagi, Nobuaki Matsui, Masaaki Akagi
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60837 (2013)
While gene knockout technology can reveal the roles of proteins in cellular functions, including in mast cells, fetal death due to gene manipulation frequently interrupts experimental analysis. We generated mast cells from mouse fetal liver (FLMC), a
Externí odkaz:
https://doaj.org/article/55fbe09b2f8b4080935f5489ab02055e
Autor:
Haruka Asai, Koichi Kato, Moe Suzuki, Misato Takahashi, Erika Miyata, Moeka Aoi, Reika Kumazawa, Fumihiro Nagashima, Hiromasa Kurosaki, Yutaka Aoyagi, Nobuyuki Fukuishi
Publikováno v:
Planta Medica. 88:1069-1077
The liverwort Radula perrottetii contains various bibenzyl derivatives which are known to possess various biological activities, such as anti-inflammatory effects. Mast cells (MC) play crucial roles in allergic and inflammatory diseases; thus, inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2ee7fb2a48e0d905dc617dadf412161
https://doi.org/10.1055/a-1750-3765
https://doi.org/10.1055/a-1750-3765
Autor:
Yoshihiro Yamaguchi, Koichi Kato, Yoshimi Ichimaru, Yuya Uenosono, Sakiko Tawara, Rio Ito, Natsuki Matsuse, Jun-ichi Wachino, Sachiko Toma-Fukai, Wanchun Jin, Yoshichika Arakawa, Masami Otsuka, Mikako Fujita, Nobuyuki Fukuishi, Kirara Sugiura, Masanori Imai, Hiromasa Kurosaki
Publikováno v:
ACS infectious diseases.
Gram-negative bacteria producing metallo-β-lactamases (MBLs) have become a considerable threat to public health. MBLs including the IMP, VIM, and NDM types are Zn(II) enzymes that hydrolyze the β-lactam ring present in a broad range of antibiotics,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::317ee2d4dcdf0f1bbdd8d3ed5fa18955
https://pubmed.ncbi.nlm.nih.gov/36519431
https://pubmed.ncbi.nlm.nih.gov/36519431
Autor:
Yoshihiro Yamaguchi, Misa Sakai, Yukina Miyagi, Yoshimi Ichimaru, Wanchun Jin, Miki Abe, Mikako Fujita, Yuriko Yamagata, Hiromasa Kurosaki, Masanori Imai, Jun-ichi Wachino, Yoshichika Arakawa, Koichi Kato, Nobuyuki Fukuishi, Masami Otsuka
Publikováno v:
Journal of Medicinal Chemistry. 64:10019-10026
The emergence and rapid spread of carbapenem-resistant pathogens producing metallo-β-lactamases such as IMP-1 and NDM-1 have been of great concern in the global clinical setting. The X-ray crystal structures of IMP-1 from Serratia marcescens and its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c1fc547eb2de7c7f426581bb09e822e
https://doi.org/10.1021/acs.jmedchem.1c00308
https://doi.org/10.1021/acs.jmedchem.1c00308
Autor:
Haruka Asai, Koichi Kato, Tomoki Nakayoshi, Yoshinobu Ishikawa, Eiji Kurimoto, Akifumi Oda, Nobuyuki Fukuishi
Publikováno v:
AppliedChem; Volume 1; Issue 2; Pages: 142-155
The deamidation of glutamine (Gln) residues, which occurs non-enzymatically under physiological conditions, triggers protein denaturation and aggregation. Gln residues are deamidated via the cyclic glutarimide intermediates to l-α-, d-α-, l-β-, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::592e70022d77551c958ff4cbab2cb506