Výsledky vyhledávání - "Nobuyuki, Oyama"

Akademický článek

Fatty acid synthase is a key target in multiple essential tumor functions of prostate cancer: uptake of radiolabeled acetate as a predictor of the targeted therapy outcome.

Autor: Yukie Yoshii, Takako Furukawa, Nobuyuki Oyama, Yoko Hasegawa, Yasushi Kiyono, Ryuichi Nishii, Atsuo Waki, Atsushi B Tsuji, Chizuru Sogawa, Hidekatsu Wakizaka, Toshimitsu Fukumura, Hiroshi Yoshii, Yasuhisa Fujibayashi, Jason S Lewis, Tsuneo Saga

Publikováno v: PLoS ONE, Vol 8, Iss 5, p e64570 (2013)

Fatty acid synthase (FASN) expression is elevated in several cancers, and this over-expression is associated with poor prognosis. Inhibitors of FASN, such as orlistat, reportedly show antitumor effects against cancers that over-express FASN, making F

Externí odkaz: https://doaj.org/article/1f05c698d43041ccb4452ef9e7cbc8d2

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