Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Nobutomo, Ikarashi"'
Autor:
Risako Kon, Nobutomo Ikarashi, Mayumi Ohkuma, Misato Toyonaga, Rei Tomimoto, Hiroyasu Sakai, Tomoo Hosoe, Junzo Kamei
Publikováno v:
BMC Research Notes, Vol 17, Iss 1, Pp 1-9 (2024)
Abstract Objectives Apples are one of the most frequently consumed fruits and are effective in preventing lifestyle-related and other diseases. However, few studies have been conducted to evaluate health benefits of processed apple products such as j
Externí odkaz:
https://doaj.org/article/cb2ae99efcfb4c738b0eb7d42df9ccfe
Autor:
Ken Sato, Yu Miyauchi, Xinran Xu, Risako Kon, Nobutomo Ikarashi, Yoshihiko Chiba, Tomoo Hosoe, Hiroyasu Sakai
Publikováno v:
Journal of Pharmacological Sciences, Vol 152, Iss 3, Pp 167-177 (2023)
Cisplatin, a platinum-based anticancer drug used frequently in cancer treatment, causes skeletal muscle atrophy. It was predicted that the proteolytic pathway is enhanced as the mechanism of this atrophy. Therefore, we investigated whether a platinum
Externí odkaz:
https://doaj.org/article/e1546edfafe64459b2b340fe15163c8e
Autor:
Risako Kon, Nobutomo Ikarashi, Arisa Yamaguchi, Yuka Teshima, Tamami Yamaguchi, Kanako Miyaoka, Moeno Fukuda, Hinata Noguchi, Rei Tomimoto, Hiroyasu Sakai, Junzo Kamei, Tomoo Hosoe
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Irinotecan (CPT-11) is an anticancer drug with indications for use in treating various cancers, but severe diarrhea develops as a side effect. We investigated the effects of green tea extract (GTE) on CPT-11-induced diarrhea, focusing on β-
Externí odkaz:
https://doaj.org/article/b16f3c60249149e4b6bb0f7dce69a11f
Autor:
Hiroyasu Sakai, Maho Asami, Hiroaki Naito, Satoko Kitora, Yuta Suzuki, Yu Miyauchi, Rei Tachinooka, Satoshi Yoshida, Risako Kon, Nobutomo Ikarashi, Yoshihiko Chiba, Junzo Kamei
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 6, Pp 1570-1581 (2021)
Abstract Background A reduction in the skeletal muscle mass worsens the prognosis of patients with various cancers. Our previous studies indicated that cisplatin administration to mice caused muscle atrophy. This is a concern for human patients recei
Externí odkaz:
https://doaj.org/article/77d597eb59bb4aeea8cec217cc2abbe3
Publikováno v:
Journal of Pharmacological Sciences, Vol 141, Iss 2, Pp 106-110 (2019)
It has recently been exhibited that Rac1 expression is increased in the bronchial tissue of a murine model with repeated antigen-challenged airway hyperresponsiveness (AHR). In the present study, the role of Rac1 in endothelin-1 (ET-1)-induced bronch
Externí odkaz:
https://doaj.org/article/dcb5b9842eb746b18e2a1f14782acc82
Autor:
Risako Kon, Nobutomo Ikarashi, Kazuhiro Onuma, Zenta Yasukawa, Makoto Ozeki, Hiroyasu Sakai, Junzo Kamei
Publikováno v:
Food Science & Nutrition. 11:1127-1133
In recent years, the development of functional foods targeting gastrointestinal disorders has been in progress. Partially hydrolyzed guar gum (PHGG), which is a water-soluble dietary fiber, is known to have a constipation-improving effect. However, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1b0893be93770296ff401606d4fa974
https://doi.org/10.1002/fsn3.3150
https://doi.org/10.1002/fsn3.3150
Autor:
Nobutomo Ikarashi, Marina Shiseki, Ryotaro Yoshida, Keito Tabata, Rina Kimura, Tomofumi Watanabe, Risako Kon, Hiroyasu Sakai, Junzo Kamei
Publikováno v:
Pharmaceuticals, Vol 14, Iss 9, p 879 (2021)
Cannabidiol (CBD) is a major nonpsychotropic component of Cannabis sativa with various pharmacological activities. In this study, we investigated the skin moisturizing effect of CBD and its mechanism. A 1% CBD solution was applied daily to skin of HR
Externí odkaz:
https://doaj.org/article/12a7eb428d9749a596237f69549124ad
Autor:
Hiroyasu, Sakai, Yujie, Zhou, Yu, Miyauchi, Yuta, Suzuki, Yohei, Ikeno, Risako, Kon, Nobutomo, Ikarashi, Yoshihiko, Chiba, Tomoo, Hosoe, Junzo, Kamei
Publikováno v:
Biological and Pharmaceutical Bulletin. 45:910-918
Cisplatin is a chemotherapy drug used to treat a variety of cancers. Muscle loss in cancer patients is associated with increased cancer-related mortality. Previously, we suggested that cisplatin administration increases the atrophic gene expressions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e46b7ab9ef683ba55067c8d31c407fa2
https://doi.org/10.1248/bpb.b22-00177
https://doi.org/10.1248/bpb.b22-00177
Autor:
Nobutomo Ikarashi, Nanaho Mizukami, Chenchen Pei, Ryogo Uchino, Izumi Fujisawa, Natsuko Fukuda, Risako Kon, Hiroyasu Sakai, Junzo Kamei
Publikováno v:
Biomedicines, Vol 9, Iss 2, p 104 (2021)
Xeroderma is induced by diabetes, reducing patients’ quality of life. We aimed to clarify the roles of cutaneous water channel aquaporin-3 (AQP3) in diabetic xeroderma using type 2 diabetes model db/db mice. Blood glucose levels were unchanged in 5
Externí odkaz:
https://doaj.org/article/3fa2008cc889431695fa1cd9bbf342ef
Autor:
Risako Kon, Nobutomo Ikarashi, Kazuhiro Onuma, Zenta Yasukawa, Makoto Ozeki, Hiroyasu Sakai, Junzo Kamei
Publikováno v:
Food Sci Nutr
The cover image is based on the Original Article Effect of partially hydrolyzed guar gum on the expression of aquaporin‐3 in the colon by Risako Kon et al., https://doi.org/10.1002/fsn3.3150 [Image: see text]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8f43516951af86da883f767c4c5c2ea
https://doi.org/10.1002/fsn3.3264
https://doi.org/10.1002/fsn3.3264