Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Nobutaka Ohkubo"'
Autor:
Nobutaka Ohkubo, Etsuko Matsubara, Jun Yamanouchi, Rie Akazawa, Mamoru Aoto, Yoji Suzuki, Ikuya Sakai, Takaya Abe, Hiroshi Kiyonari, Seiji Matsuda, Masaki Yasukawa, Noriaki Mitsuda
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92848 (2014)
Zinc finger protein 521 (ZFP521) regulates a number of cellular processes in a wide range of tissues, such as osteoblast formation and adipose commitment and differentiation. In the field of neurobiology, it is reported to be an essential factor for
Externí odkaz:
https://doaj.org/article/dd4c044085d8407789bb6867ddecd42a
Autor:
Akiho Iwashita, Noriaki Mitsuda, Mamoru Aoto, Kanako Mita, Yoshihide Tsujimoto, Nobutaka Ohkubo
Publikováno v:
FEBS Open Bio
Enucleation is the process whereby the nucleus is extruded from the erythroblast during late stage mammalian erythropoiesis. However, the specific signaling pathways involved in this process remain unclear. To better understand the mechanisms underly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e01a7bbdf732c7064aea2ae0a62a71f
https://doi.org/10.1002/2211-5463.12573
https://doi.org/10.1002/2211-5463.12573
Publikováno v:
Life sciences. 231
Aim Previously, we reported that mice deficient in most of the Zfp521 coding region (Zfp521Δ/Δ mice) displayed abnormal behaviors, including hyperlocomotion and lower anxiety. In this study, we aimed to elucidate the involvement and mechanisms of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cea7fc84dc0b2d3fcf2c5cc69aee7401
https://pubmed.ncbi.nlm.nih.gov/31200001
https://pubmed.ncbi.nlm.nih.gov/31200001
Autor:
Jun Yamanouchi, Yoji Suzuki, Noriaki Mitsuda, Nobutaka Ohkubo, Mamoru Aoto, Satoshi Hirakawa, Masaki Yasukawa
Publikováno v:
Life Sciences. 93:380-387
AimsSTAT3 is a key modulator of activation and differentiation of macrophages. But it is still unknown if deficiency of STAT3 activates macrophages to destroy erythrocytes by phagocytosis. We generated STAT3 conditional knockout mice by crossing flox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66cd69b2f042df5b0f2ee1dfc5d9e2c4
https://doi.org/10.1016/j.lfs.2013.07.025
https://doi.org/10.1016/j.lfs.2013.07.025
Autor:
Nobutaka Ohkubo, Masahiro Sakanaka, Yoji Suzuki, Noriaki Mitsuda, Mamoru Aoto, Keiichi Samukawa
Publikováno v:
Biorheology. 45:689-700
The extract from Panax ginseng has been reported to improve the microcirculation in various organs. However, the mechanisms underlying this phenomenon are still poorly understood. In the present study, using the rheological properties of erythrocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf39470928090363a99a07646a8316e
https://doi.org/10.3233/bir-2008-0516
https://doi.org/10.3233/bir-2008-0516
Autor:
Nobutaka Ohkubo, Tetsuro Miki, Atsuyuki Morishima, Yoji Suzuki, Noriaki Mitsuda, Nobuji Maeda, Michael P. Vitek
Publikováno v:
Journal of Neurochemistry. 103:820-830
Reelin plays an important role in the migration of embryonic neurons, but its continuing presence suggests additional functions in the brain. We now report a novel function where reelin protects P19 embryonal cells from apoptosis during retinoic acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57b4e4599ac70a78e5704cf60227aad9
https://doi.org/10.1111/j.1471-4159.2007.04804.x
https://doi.org/10.1111/j.1471-4159.2007.04804.x
Publikováno v:
Journal of Biological Chemistry. 278:38188-38193
The levels of plasma HDL cholesterol and apoA-I in NFkappaB p50 subunit-deficient mice were significantly higher than those in wild-type mice under regular and high fat diets, without any significant difference in the level of total cholesterol. To e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae308890dd39dc51b298b7332db8ac3d
https://doi.org/10.1074/jbc.m306336200
https://doi.org/10.1074/jbc.m306336200
Autor:
Naoyuki Sato, Noriaki Mitsuda, Kei Yamamoto, Shinichi Yoshimura, Masaki Mori, Toshio Ogihara, Hironori Nakagami, Nobutaka Ohkubo, Ryuichi Morishita, Yasufumi Kaneda
Publikováno v:
Life Sciences. 70:2567-2580
A missense mutation (N1411) in Presenilin-2 (PS-2) gene is associated with early-onset familial Alzheimer's disease. In this study, SK-N-SH human neuroblastoma cells were transfected with wild-type and mutant PS-2 gene to examine presenilin-2 effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::032b595875646bd6e2086d2659d986db
https://doi.org/10.1016/s0024-3205(02)01514-x
https://doi.org/10.1016/s0024-3205(02)01514-x
Autor:
Yoji Suzuki, Rie Akazawa, Nobutaka Ohkubo, Mamoru Aoto, Etsuko Matsubara, Seiji Matsuda, Hiroshi Kiyonari, Masaki Yasukawa, Jun Yamanouchi, Noriaki Mitsuda, Ikuya Sakai, Takaya Abe
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92848 (2014)
PLoS ONE
PLoS ONE
Zinc finger protein 521 (ZFP521) regulates a number of cellular processes in a wide range of tissues, such as osteoblast formation and adipose commitment and differentiation. In the field of neurobiology, it is reported to be an essential factor for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f0b65ebd590163bd978175f26e2772d
http://europepmc.org/articles/PMC3968043?pdf=render
http://europepmc.org/articles/PMC3968043?pdf=render
Autor:
Masaya Tohyama, Michael P. Vitek, Nobutaka Ohkubo, Toshio Ogihara, Noriaki Mitsuda, Atsushi Yamaguchi, Michio Tamatani, Young-Don Lee
Publikováno v:
Journal of Biological Chemistry. 276:3046-3053
Inheritance of the epsilon4 allele of the apolipoprotein E gene (APOE4) is a major risk factor for the development of Alzheimer's disease (AD). Although the association between APOE4 and AD is well documented, the mechanism by which apolipoprotein E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb08fc42a838ace6c469413c2b9e1e3
https://doi.org/10.1074/jbc.m005070200
https://doi.org/10.1074/jbc.m005070200