Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Nobutaka Matsumura"'
Autor:
Hirokazu Shiheido, Fukiko Terada, Noriko Tabata, Ichigo Hayakawa, Nobutaka Matsumura, Hideaki Takashima, Yoko Ogawa, Wenlin Du, Taketo Yamada, Mitsuru Shoji, Takeshi Sugai, Nobuhide Doi, Shiro Iijima, Yutaka Hattori, Hiroshi Yanagawa
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38878 (2012)
Despite the introduction of newly developed drugs such as lenalidomide and bortezomib, patients with multiple myeloma are still difficult to treat and have a poor prognosis. In order to find novel drugs that are effective for multiple myeloma, we tes
Externí odkaz:
https://doaj.org/article/39b2b178d8884a0d95e69700689dc38f
Autor:
Nobuhide Doi, Natsuko Yamakawa, Hideaki Matsumoto, Yasutsugu Yamamoto, Tetsuya Nagano, Nobutaka Matsumura, Kenichi Horisawa, Hiroshi Yanagawa
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30084 (2012)
The G protein-coupled receptors (GPCRs), which form the largest group of transmembrane proteins involved in signal transduction, are major targets of currently available drugs. Thus, the search for cognate and surrogate peptide ligands for GPCRs is o
Externí odkaz:
https://doaj.org/article/20365f26da924cec848127af563d1896
Autor:
Nobutaka Matsumura
Publikováno v:
Conceptions of Giftedness ISBN: 9781003064435
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d390e7853c7c43d6e398c904b08e334f
https://doi.org/10.4324/9781003064435-12
https://doi.org/10.4324/9781003064435-12
Autor:
Yasuo Ihara, Shinji Tagami, Nobutaka Matsumura, Satoko Wada-Kakuda, Hitomi Fujiwara, Mako Takami, Maho Morishima-Kawashima, Masayasu Okochi, Satoru Funamoto
Publikováno v:
Journal of Biological Chemistry. 289:5109-5121
γ-Secretase generates amyloid β-protein (Aβ), a pathogenic molecule in Alzheimer disease, through the intramembrane cleavage of the β-carboxyl-terminal fragment (βCTF) of β-amyloid precursor protein. We previously showed the framework of the γ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7c2d2cc977fa74329c51a7590d85765
https://doi.org/10.1074/jbc.m113.510131
https://doi.org/10.1074/jbc.m113.510131
Autor:
Hideaki Takashima, Etsuko Miyamoto-Sato, Masaru Tomita, Masako Hasebe, Shunichi Kosugi, Hiroshi Yanagawa, Nobutaka Matsumura
Publikováno v:
Journal of Biological Chemistry. 284:478-485
The importin alpha/beta pathway mediates nuclear import of proteins containing the classical nuclear localization signals (NLSs). Although the consensus sequences of the classical NLSs have been defined, there are still many NLSs that do not match th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24227522cea44fabe3418ec76d6e3be8
https://doi.org/10.1074/jbc.m807017200
https://doi.org/10.1074/jbc.m807017200
Publikováno v:
Current Proteomics. 3:199-215
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc5fda21c1ce81cabc8ffc14284b3666
https://doi.org/10.2174/157016406779475371
https://doi.org/10.2174/157016406779475371
Publikováno v:
The American Journal of Pathology. 154:1649-1656
Extensive neuronal loss and aggregation of tau as cytoplasmic inclusions in neurons and glial cells in selected cortical and subcortical regions is the most striking characteristic of frontotemporal dementia and parkinsonism linked to chromosome 17,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c1b8297d6b1fc0eb8654ff45f248d0a
https://doi.org/10.1016/s0002-9440(10)65420-x
https://doi.org/10.1016/s0002-9440(10)65420-x
Autor:
Fukiko Terada, Nobutaka Matsumura, Yutaka Hattori, Taketo Yamada, Takeshi Sugai, Wenlin Du, Noriko Tabata, Ichigo Hayakawa, Hiroshi Yanagawa, Hideaki Takashima, Mitsuru Shoji, Nobuhide Doi, Shiro Iijima, Hirokazu Shiheido, Yoko Ogawa
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 6, p e38878 (2012)
PLoS ONE, Vol 7, Iss 6, p e38878 (2012)
Despite the introduction of newly developed drugs such as lenalidomide and bortezomib, patients with multiple myeloma are still difficult to treat and have a poor prognosis. In order to find novel drugs that are effective for multiple myeloma, we tes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51ac17233349e714d97b658993027e32
http://europepmc.org/articles/PMC3382596
http://europepmc.org/articles/PMC3382596
Autor:
Toru Tsuji, Nobutaka Matsumura, Takeshi Sumida, Etsuko Miyamoto-Sato, Hideaki Takashima, Nobuhide Doi, Masahito Kokubo, Hiroshi Yanagawa, Michiko Onimaru
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 24(7)
Bcl-X(L), an antiapoptotic member of the Bcl-2 family, is a mitochondrial protein that inhibits activation of Bax and Bak, which commit the cell to apoptosis, and it therefore represents a potential target for drug discovery. Peptides have potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e453ab9b02a8eda437a882ba02a2888
https://pubmed.ncbi.nlm.nih.gov/20181936
https://pubmed.ncbi.nlm.nih.gov/20181936
Autor:
Den-Mo Tsai, Chwee Geok Quek, N. Shane Phillipson, Seokhee Cho, Guofeng Zhang, Nobutaka Matsumura, Jiannong Shi
Publikováno v:
International Handbook on Giftedness ISBN: 9781402061615
Despite sharing a common cultural heritage, recent developments in gifted education in several countries and regions within East Asia, including the People’s Republic of China (mainland China), Taiwan, the Hong Kong Special Administrative Region (S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eebd92314a9873b62a239170806e9579
https://doi.org/10.1007/978-1-4020-6162-2_75
https://doi.org/10.1007/978-1-4020-6162-2_75