Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Nobutaka Doe"'
Autor:
Shuichi Fujiwara, Akiko Nakano-Doi, Toshinori Sawano, Shuji Kubo, Nobutaka Doe, Takayuki Nakagomi
Publikováno v:
Cells, Vol 13, Iss 11, p 939 (2024)
Increasing evidence shows that the administration of mesenchymal stem cells (MSCs) is a promising option for various brain diseases, including ischemic stroke. Studies have demonstrated that MSC transplantation after ischemic stroke provides benefici
Externí odkaz:
https://doaj.org/article/ac31ad81c90c40e7b854a510dd0241fd
Autor:
Yasunori Yoshida, Yuki Takeda, Kenichi Yamahara, Hanae Yamamoto, Toshinori Takagi, Yoji Kuramoto, Akiko Nakano-Doi, Takayuki Nakagomi, Toshihiro Soma, Tomohiro Matsuyama, Nobutaka Doe, Shinichi Yoshimura
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Umbilical cord blood (UCB) transplantation shows proangiogenic effects and contributes to symptom amelioration in animal models of cerebral infarction. However, the effect of specific cell types within a heterogeneous UCB population are stil
Externí odkaz:
https://doaj.org/article/3c1c212222c54d4cb8c75b2fef71e0f8
Autor:
Kyosuke Yamanishi, Nobutaka Doe, Keiichiro Mukai, Takuya Hashimoto, Naomi Gamachi, Masaki Hata, Yuko Watanabe, Chiaki Yamanishi, Hideshi Yagi, Haruki Okamura, Hisato Matsunaga
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Interleukin-18 (IL18) is an inflammatory cytokine that is related to psychiatric disorders such as depression and cognitive impairment. We previously found that IL18 deficiency may cause hippocampal impairment, resulting in depression-like b
Externí odkaz:
https://doaj.org/article/7e9d891138304446a4c48cacf658a1c5
Autor:
Yoji Kuramoto, Mitsugu Fujita, Toshinori Takagi, Yuki Takeda, Nobutaka Doe, Kenichi Yamahara, Shinichi Yoshimura
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-19 (2022)
Abstract Background Intracerebral hemorrhage (ICH) is a significant cause of death and disabilities. Recently, cell therapies using mesenchymal stem cells have been shown to improve ICH-induced neurobehavioral deficits. Based on these findings, we de
Externí odkaz:
https://doaj.org/article/01eea14a7c55467e838e64c07f37b355
Autor:
Yasunori Yoshida, Toshinori Takagi, Yoji Kuramoto, Kotaro Tatebayashi, Manabu Shirakawa, Kenichi Yamahara, Nobutaka Doe, Shinichi Yoshimura
Publikováno v:
Cell Transplantation, Vol 30 (2021)
Neuro-inflammation plays a key role in the pathophysiology of brain infarction. Cell therapy offers a novel therapeutic option due to its effect on immunomodulatory effects. Amniotic stem cells, in particular, show promise owing to their low immunoge
Externí odkaz:
https://doaj.org/article/2eeef86ec1e243f79c8bde1b1a1ac14a
Autor:
Yasue Tanaka, Nami Nakagomi, Nobutaka Doe, Akiko Nakano-Doi, Toshinori Sawano, Toshinori Takagi, Tomohiro Matsuyama, Shinichi Yoshimura, Takayuki Nakagomi
Publikováno v:
Cells, Vol 9, Iss 6, p 1374 (2020)
Ischemic stroke is a critical disease caused by cerebral artery occlusion in the central nervous system (CNS). Recent therapeutic advances, such as neuroendovascular intervention and thrombolytic therapy, have allowed recanalization of occluded brain
Externí odkaz:
https://doaj.org/article/71e5269e4fa64e968d36815686509990
Autor:
Kyosuke Yamanishi, Nobutaka Doe, Miho Sumida, Yuko Watanabe, Momoko Yoshida, Hideyuki Yamamoto, Yunfeng Xu, Wen Li, Hiromichi Yamanishi, Haruki Okamura, Hisato Matsunaga
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119021 (2015)
Major depressive disorder (MDD) is a common psychiatric disorder that involves marked disabilities in global functioning, anorexia, and severe medical comorbidities. MDD is associated with not only psychological and sociocultural problems, but also p
Externí odkaz:
https://doaj.org/article/06980fe1a372489291989b4792084c1c
Autor:
Shogo Matsuyama, Nobutaka Doe, Naoki Kurihara, Katsuyuki Tanizawa, Shun’ichi Kuroda, Hiroyuki Iso, Masato Horie
Publikováno v:
Journal of Pharmacological Sciences, Vol 98, Iss 3, Pp 239-243 (2005)
NELL2 is a neuron-specific thrombospondin-1-like extracellular protein containing six epidermal growth factor-like domains. We previously disrupted the NELL2 gene in mice by gene targeting and showed that long-term potentiation is enhanced in vivo in
Externí odkaz:
https://doaj.org/article/c9de5da95b0149dc989f658b947f75b0
Autor:
Mototaka Nakama-Kitamura, Nobutaka Doe
Publikováno v:
Journal of Pharmacological Sciences, Vol 92, Iss 3, Pp 237-244 (2003)
The response latencies of the biting response in the tail-pinch test and step-through response in the passive avoidance test were measured in mice. 1) Scopolamine decreased the latency of the step-through response in the passive avoidance test, but d
Externí odkaz:
https://doaj.org/article/bfc4df62af2145cea9fc80a2041cf084
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50824 (2012)
Diketopiperazines (DKPs) are naturally-occurring cyclic dipeptides with a small structure and are found in many organisms and in large amounts in some foods and beverages. We found that a chicken essence beverage, which is popular among Southeast Asi
Externí odkaz:
https://doaj.org/article/c233e9696e094fbdad2fd1b65ab12b21